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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: Q2G1H9_STAA8 (Q2G1H9)

Summary

This is the summary of UniProt entry Q2G1H9_STAA8 (Q2G1H9).

Description: Acyl-CoA synthetase {ECO:0000256|ARBA:ARBA00019604}
Source organism: Staphylococcus aureus (strain NCTC 8325 / PS 47) (NCBI taxonomy ID 93061)
Length: 2391 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam Condensation 6 177
disorder n/a 161 171
disorder n/a 382 385
Pfam AMP-binding 418 807
disorder n/a 695 697
low_complexity n/a 700 708
disorder n/a 705 709
Pfam AMP-binding_C 815 887
Pfam PP-binding 913 977
Pfam Condensation 993 1411
coiled_coil n/a 1033 1053
low_complexity n/a 1139 1153
disorder n/a 1339 1342
Pfam AMP-binding 1443 1835
disorder n/a 1571 1576
Pfam AMP-binding_C 1843 1914
disorder n/a 1912 1933
Pfam PP-binding 1939 2005
Pfam NAD_binding_4 2049 2284

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q2G1H9. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MIMGNLRFQQ EYFRIYKNNT ESTTHRNAYW VKLAKNVEAT KMMYALSTIV
50
51
QQHASIRHFF DVTTDDNLTM ILHEFLPFIE IKQVPSSSAN YDLEAFFKQE
100
101
LSTYHFNDSP LFKVKLFQFA DAAYILLDFH VSIFDDSQID IFLDDLCNAY
150
151
RGNTVINNTR QHAHINRNDD KDNQDASHIA LDSNYFRLEN NSDIHIDSYF
200
201
PIKHPFEQAL YQTYLIDDMT SIDMASLAVS VYLANHIMSQ QHDVTLGIHV
250
251
PSHLPNDLHG NIVPLTLTID AKDVCQRFTT DFNKCVLQNM SQLQCAKSSL
300
301
SLETIFHCYH HMMSCCNDVI EDVHQIHDAH TSLADIEIFP HQHGFKIIYN
350
351
SAAYDLLSIE TLSDLVRNIY LQITEENGNK RTTVDELNLM TERDIQLYDD
400
401
INLSLPEIDD AQTVVTLFEQ QVEATPNHVA VQFDGVFITY QTLNARANDL
450
451
AHRLRNQYGV EPNDRVAVIA EKSIEMIIAM IGVLKAGGAY VPIDPNYPSD
500
501
RQEYILKDVT PKVVITYQAL YENGKQNINH IDLNKIAWKN IDNLSKCNTL
550
551
EDHAYVIYTS GTTGNPKGTL IPHRGIVRLV HQNHYVPLNE ETTILLSGTI
600
601
AFDAATFEIY GALLNGGKLI VAKKEQLLNP IAVEQLINEN DVNTMWLTSS
650
651
LFNQIASERI EVLVPLKYLL IGGEVLNAKW VDLLNQKPKH PQIINGYGPT
700
701
ENTTFTTTYN IPNKVPNRIP IGKPILGTHV YIMQGERRCG VGIPGELCTS
750
751
GFGLAAGYLN QPELTADKFI KDSNINQLMY RSGDIVRLLP DGNIDYLYRK
800
801
DKQVKIRGFR IELSEVEHAL ERIQGINKAV VIVQNHDQDQ YIVAYYEAMH
850
851
TLSHNKIKSQ LRMTLPEYMI PVNFMHIEQI PITINGKLDK KALPIMDYVD
900
901
TDAYVAPSTD TEHLLCQIFA DILHVNQVGI HDNFFELGGH SLKATLVVNR
950
951
IEASTGKRLQ IGDLLQKPTV FELAQAIAKV QEQNYEVIPE TIVKDDYVLS
1000
1001
SAQKRMYLLW KSNHKDTVYN VPFLWRLSSE LNVAQLRQAV QRLIARHEIL
1050
1051
RTQYIVVDDE VRQRIVADVA VDFEEVNTHF TDEQEIMRQF VAPFNLEKPS
1100
1101
QIRVRYIRSP LHAYLFIDTH HIINDGMSNI QLMNDLNALY QHKLLLPLKL
1150
1151
QYKDYSEWMS HRDMTKHRQY WLSQFKDEVP ILSLPTDYVR PNIKTTNGAM
1200
1201
MSFTMNQQMR QLLQKYVEKH QITDFMFFMS VVMTLLSRYA RKDDVVVGSV
1250
1251
MSARMHKGTE QMLGMFANTL VYRGQPSPDK MWTQFLQEVK EMSLEAYEHQ
1300
1301
EYPFECLVND LDQSHDASRN PLFDVMLVLQ NNETNHAHFG HSKLTHIQPK
1350
1351
SVTAKFDLSF IIEEDRDDYT INIEYNTDLY HSETVRHMGN QCMIMIDYIL
1400
1401
KHQDTLQICD IPNGTEELLN WVNTHVNDRM LNVPGNKSII SYFNEVVSRQ
1450
1451
GNHVALVMND LTMTYETLRN YVDAIAHMLL SNGVGNGQRV ALFTERSFEM
1500
1501
IAAMLATVKV GASYIPIDID FPNKRQGAIL EDAKVTAVMS YGVEIETTLP
1550
1551
VIQLENAKGF VESKENEQYD DLHGNQLENT AMLDNEMYAI YTSGTTGMPK
1600
1601
GVAIRQRNLL NLVHAWSTEL QLGDNEVFLQ HANIVFDASV MEIYCCLLNG
1650
1651
HTLVIPDREE RVNPEQLQQL INKHRVTVAS IPLQMCSVME DFYIEKLITG
1700
1701
GATSTASFVK YIEKHCGTYF NAYGPSESTV ITSYWSHHCG DLIPETIPIG
1750
1751
KPLSNIQVYI MSDGLLCGIG MPGELCIAGD SLAIGYINRP ELMADKWQNN
1800
1801
PFGKGKLYHS GDLARYTSDG QIEFLGRIDK QVKVNGYRIE LDEIENAILA
1850
1851
IRGISDCVVT VSHFDTHDIL NAYYVGEQQV EQDLKQYLND QLPKYMIPKT
1900
1901
ITHIDCMPLT TNDKVDTTRL PNPSPIQQSN KVYSEPSNEI EQTFVDVFGE
1950
1951
VLKQNDVGVD DDFFELGGNS LEAMLVVSHL KRFGHHISMQ TLYQYKTVRQ
2000
2001
IVNYMYQNQQ SLVALPDNLS ELQKIVMSRY NLGILEDSLS HRPLGNTLLT
2050
2051
GATGFLGAYL IEVLQGYSHR IYCFIRADNE EIAWYKLMTN LNDYFSEETV
2100
2101
EIMLSNIEVI VGDFECMDDV VLPENMDTII HAGARTDHFG DDDEFEKVNV
2150
2151
QGTVDVIRLA QQHHARLIYV STISVGTYFD IDTEDVTFSE ADVYKGQLLT
2200
2201
SPYTRSKFYS ELKVLEAVNN GLDGRIVRVG NLTNPYNGRW HMRNIKTNRF
2250
2251
SMVMNDLLQL DCIGVSMAEM PVDFSFVDTT ARQIVALAQV NTPQIIYHVL
2300
2301
SPNKMPVKSL LECVKRKEIE LVSDESFNEI LQKQDMYETI GLTSVDREQQ
2350
2351
LAMIDTTLTL KIMNHISEKW PTITNNWLYH WAQYIKTIFN K         
2391
 

Show the unformatted sequence.

Checksums:
CRC64:2643994D27FB53F4
MD5:b009586cfcbbb66a6d19e10fa35883ef

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;