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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: Q4DCH1_TRYCC (Q4DCH1)

Summary

This is the summary of UniProt entry Q4DCH1_TRYCC (Q4DCH1).

Description: Phosphatidylinositol 3-kinase 2, putative {ECO:0000313|EMBL:EAN90227.1}
Source organism: Trypanosoma cruzi (strain CL Brener) (NCBI taxonomy ID 353153)
Length: 1055 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam PI3K_rbd 178 253
Pfam PI3K_C2 329 508
disorder n/a 475 476
Pfam PI3Ka 528 711
low_complexity n/a 657 664
Pfam PI3_PI4_kinase 793 1007
transmembrane n/a 891 911

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q4DCH1. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSSPSELFEG LKVDFREELE AEDIYGSKNS EGFERLFERS EKCKRNVTQL
50
51
STILQSLIFQ ENEIETEGEL EAIIEYIVGT GLYGQSSSLE AKEFRKKIRA
100
101
SFEYEWHEFQ KENSFISSSR AMRTLPYRFS LPSLEKAQLE MLTELSSRGM
150
151
SNGSLGTVLL RIWYIDLVGC TCSTLRGFPF DMKASDAILI TMERLFLITN
200
201
FDKSKSQGIM YVFKIQGRKE YVYGDEILIN FCYIRDSVTQ QREVNVVVEP
250
251
HEKTLLTDPI FVPSYSYFSK TSDENHHVFY KSESPDDIST GISVWDIEGK
300
301
LVVKIGENLC NLVFTSERAK EEGVREGDLL YLALLVEVYH GAKLVCRPQM
350
351
TKWTVCNDLV ASNELTTSSS VNWGKETKLT FDMLVSNAPR EIKLCISLLA
400
401
TCGERFCSVN SLSAEEIVQK AEERIGVKKM EECHLSPVFF LGYASVQVFD
450
451
YMACMQTGKL DMRLWSTKKK ANPMCPIPKN SNKNDMGFSL IFPSFNKPVV
500
501
IPNVAPPDSK RRDWEQQLLD SDLCLVGNLR ESKIEQLRQL KRILASDPLT
550
551
ELTTIDKVLL WKHRGELILR PRALAKFLLA VNWLRPYAVY EAHTILPQWA
600
601
PLQPMDALEL LDIRYADIVV REHAVKYLNG MTDYELKGCV LQLVQVLKHE
650
651
PYHDSALFRF LLRRSLQSPH MIGHYVFWYL VSEMENTSVS ERYGLLLEEL
700
701
IRRMPERKVY LRQLYLADQL FECAMRVKDA PKKDRIDCLR EHLQGLRLPR
750
751
RFTLPINPAM ECSGLDIGKC KVMDSKKFPL WLVFRNYQEE GDPFYVIFKA
800
801
GDDLRQDLFT LQLLELMDSL WKSCGLYLHI IPYGCITTGE GVGMIEVVLN
850
851
SDTVANITRK YGGAQAAFRE EPLMNWLRQF NRERDEVERC LWNFICSVAG
900
901
YTVATYVLGI GDRHNDNIML RQDGTLFHID FGHFLGNFKT KFGIKRETAP
950
951
FIFTPMYVYM LGGQSSPIYL YFVDLACHAF NVVRRFGGTL MTHFMLMLST
1000
1001
GIPELQKIED IGWLRTVLLI DRSSEEAREH YRLQIALATS NFRTLFNDYI
1050
1051
HIMTH                                                 
1055
 

Show the unformatted sequence.

Checksums:
CRC64:D0F9D2CCA647AB65
MD5:f0c57293328d4d504db33ae7b2d7cc53

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;