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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: Q4DMH7_TRYCC (Q4DMH7)

Summary

This is the summary of UniProt entry Q4DMH7_TRYCC (Q4DMH7).

Description: DNA ligase, putative {ECO:0000313|EMBL:EAN93729.1}
Source organism: Trypanosoma cruzi (strain CL Brener) (NCBI taxonomy ID 353153)
Length: 521 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 43 47
disorder n/a 119 154
low_complexity n/a 151 160
Pfam DNA_ligase_A_M 194 429
disorder n/a 203 204
disorder n/a 206 207
disorder n/a 215 216
disorder n/a 357 367
Pfam DNA_ligase_OB_2 443 513

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q4DMH7. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MVVARIGART EMWRRCSCLG RAIVQSVDPS LLFGAGRPRT KQQAEKYKEL
50
51
KNTTIQAAFP HLAACWVGPC WGTVMITPHH ISPLCLKMAV WRCSECLQEF
100
101
EMSIAKFVDQ HGVCPLCKKP QRSLETPNKE PETTNGSSTE GKNGDSNLGS
150
151
ATAMTMTTTT KNELVYAKAP RMIHTNYRSV LHDNPEWEEI NIQPMLAQKW
200
201
ETVAAELLNP GPGEEKELLL ASPKIDGIRC LIGYNRRRKE PKFFSRGGIL
250
251
LECCHGLVPH VMPLFEADPT LVLDGELFAP QCNFEELNGL VRRLEKFTTP
300
301
EMRERQAQLL EYFSFDIMHS SQLSSPTAPF SERYRLLKKM VPTCGAKRIS
350
351
AYQHDEEKRK IIRQKQRPDN AAAEGTIKLY HVPAAQVGAE EMDEVLEEAC
400
401
SQGFEGVMIR RPGFPYEHGK RSFGLLKYKT MHDAEYRIVD FLPGQGKFRG
450
451
GLGAFICETK TGIRFNATPK TTYENRLALW GKRQELLGKY LTVQYQELSS
500
501
QDVPRFPVAK AVRGASEEEF L                               
521
 

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Checksums:
CRC64:B8460542FC3007F0
MD5:581b13a28174c90204377c236ab6c047

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;