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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: Q4DX34_TRYCC (Q4DX34)

Summary

This is the summary of UniProt entry Q4DX34_TRYCC (Q4DX34).

Description: Non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513}
Source organism: Trypanosoma cruzi (strain CL Brener) (NCBI taxonomy ID 353153)
Length: 2592 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
low_complexity n/a 663 671
Pfam DUF3385 718 883
low_complexity n/a 767 783
low_complexity n/a 872 882
Pfam PDZ_6 1358 1408
low_complexity n/a 1365 1380
Pfam FAT 1584 1900
Pfam FRB_dom 2007 2094
disorder n/a 2056 2060
Pfam PI3_PI4_kinase 2161 2415
disorder n/a 2271 2272
disorder n/a 2424 2448
disorder n/a 2450 2452
disorder n/a 2526 2528
Pfam FATC 2560 2592

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q4DX34. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTDAAEPSID RFFKESASAL GRQFSIIFRN LQSAPESRLR RVNECLSDLL
50
51
DLLVAHTKEI IELGLLDHIF QLVNETFDGS VKRGIQALRV VFDAHLGDQH
100
101
EERSRCVALL MRQAARGKCE EDCAFMLNEL GEVLQENVRS TSDMLGRHLN
150
151
RAIVMMRQGA TVHERAVGCQ ILATMVETSS SVIKRNPALL DSLNATCSPL
200
201
FLLRETVESF SMWHRHALVG LLKNIVEKHC IEISPFMATQ MSAVMTEFME
250
251
NADENVIIVG LLTAIETVAA SPTLQSAPWH LKKIHSFLME RDWNTYPKEV
300
301
CIMVPRATGK ALLLFRDDEG LYYGIMRCFL SYLSDWEEDV AVVALSTLYD
350
351
ILGEVNIAPH VELAVDVIAH FIVKFPFYQL PFDALERLRA QCGEQSVARI
400
401
YTLFDIIGID MEYTNLQKLS ALLRFMGDRK QSIWERFRLL QIDISPHVPV
450
451
DVLVRALPFL ATLGRTEQIG ELIDLMFHEN LKVRQAAVDA VVILCEKLIL
500
501
QSRSNDNIHQ LTQRLDNTVT SAVGKLLDVA VADRDAELRY NVLCRFSPLF
550
551
DAYLSLQDHL DALLMARNDV SRRARDRTLV LLCRLHPCNP AIVHSQLLRQ
600
601
QEYMLREIEA KDGSMSAAIY QASLLQMTAE HDRLLLQPRT VELAVLARLQ
650
651
REPFASKSFS VALLNLLRLI LDRTGPHNHC DANQLLQPVI HIVNGSTSSR
700
701
RRKAALETLC SILTTIRVTK QSSYVVVYLA LARIIRSEAE EDEGVNYAAM
750
751
KALSVIGAVN PVKLRFILKA LEDDEIEEAE EVVTSALACY KPRMRVHPHM
800
801
TERYPSIVLY LLVKTLQQSA DPEQQAGTIA TINSMVREIP GNQKAILLTH
850
851
FLPQLQSWLA DPERDHLYEG ILLLMTELAT LLRQFKDVIP SNTGSELLHS
900
901
VRQFCLLPQA SQKPLNAGVV ELLDEVARGL SAQEMRDHRW AVEFIHQRLS
950
951
QDKNDLDLVL RAVKSLESFL AVLHEKDLQV VLPHVLQCIE PEDATPSALR
1000
1001
PKAKDINAAC FDFLNQIMVK QPLLVKDCCA EIVHTVMWYI EKSKSQDEME
1050
1051
MGFNTLAFLV EVVNRQAKRF ILPIRRLAEQ KGFSEAMFTD LLNSAARGFL
1100
1101
KVRVPVTKQD KLDPDLPLSV VSHLPGLSRK DFEEEMMNTL NLGGDDFEVM
1150
1151
DVSHPSGQTI INLRFFGGDD SAANFRSFTR KAQETQSVLR RNLGILKLDQ
1200
1201
TQLNECKVDE ALLQKIATIP VANKKKREQS WIAWLHKTSV EMLANSQIQP
1250
1251
LRCTAELAKY NSDLSRDLFS FAAAAFIAQL DKNQRALVMD TFTRALEMSP
1300
1301
NDIKQILFGF AEFFESERGK NELVLVKRIE TMNCVVERED TEKKFGINYD
1350
1351
QNARGIAVTK LEPNGPGAKA GVPVGALLVA INGKKVSAVS EIVSNIRGEK
1400
1401
KISLTLKYEV EEQRKPESEP LMDLEVLARV AFDSQMHAKA IFLNEVLFDQ
1450
1451
LFNGLGEQVS GRQDAAVRSA LQVAERLIEF YDHLGLNMVA KGLVKKMSAK
1500
1501
FSGKIIAPEQ FGFDEVGALE QLNWWGEALA RYESRMMNTD GSINTSSLLG
1550
1551
VLRCLDALGE AIEMEVLINR NWHQLDRESR FEVAPLKAKV ALSLGRWQQF
1600
1601
DELTEQSGVM ERLGMVERCA TLFRQRQYEE LLEFTKERRE SLFDLFSESF
1650
1651
MESYNRAYDM LVELQHLRHF EELVSFVNSG EERQRMLKEL WQTRLAHMSS
1700
1701
RPAQVKTLIT INSLVLTPAM DLTSQVMCIR ALSKSQWTSF ADHMLNLLLG
1750
1751
PTGDYQALCR QDPDVIHVYM KHCYTTKNRR ETLRLLSEIL ARLQVSPGDD
1800
1801
RAEAWGSCWL LLGEWTMHLF PDKGDEAIEQ LKKATELCPR NHLAFHSLGI
1850
1851
LHYDMSRDPN TPVEVQTAHH VGSITALFKS VELSSNQGNG VMEDVLRILS
1900
1901
IWFSHSALLE INEAIKEGID RVPDYVWLKV IPQLVARIGI TAKVARSILT
1950
1951
ELLVRVGSKY PHALIYPLTV TEKSPEAIRQ LMAERVLKGI RVSNGPMVGE
2000
2001
ASLISNEMVR IAILWAEKWH SHIQQAAGKQ NDVNAILRIF GPLFWELENP
2050
2051
KTPNECAFEK TYGPTLRHAK AALQNNTLDQ AWSLLKQVYV QLNKTTGERR
2100
2101
LLMGDLSPTL GGIKESIVAV PGSFVLGQPL ITIQKFHQAV IVMPSKQKPR
2150
2151
RFGLDASNGQ KYRFLLKGHE DLRQDERVMQ FIEFVNTIFF ADSSSSAIGL
2200
2201
SIPQYAVIPL TDNVGIIGWV ENTETIYRML ETRRKEHSIS IYEEVRMIVR
2250
2251
NGALRNIEEY HHQSKEQRKN LLSQVFNNTP DNELRRIIWD KNDTCEQWLE
2300
2301
YRGTYGHTLA IMSMVGYVLG LGDRHLNNLM LQEKGSVVHI DFGDCFEVAM
2350
2351
HRSLYAEAVP FRLTRLLVSA LGISGVDGVY RLTCELVMKN LRRHCENLLS
2400
2401
ILEAFIYDPL INWRLANVGD GERSSSRAEA HVKTGDNTLL NPGETNTKEP
2450
2451
QMQLSYSVAR VREFVACATL DQLNEEETRN MQGDLALARV RAKLTGEDFD
2500
2501
AMNGSSVLQN SRREFCDESG DASSCGSQSY GDSQKDSFAI GNPALTTYLS
2550
2551
LRAVNGSANC LDVPHQVDRL IQEATSLDNL AEAYITGWAP FW        
2592
 

Show the unformatted sequence.

Checksums:
CRC64:5CB811D19E285933
MD5:49009b65f7b516e7281d3be9933ec960

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;