Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PKS42_DICDI (Q54D44)

Summary

This is the summary of UniProt entry PKS42_DICDI (Q54D44).

Description: Probable polyketide synthase 42 EC=2.3.1.-
Source organism: Dictyostelium discoideum (Slime mold) (NCBI taxonomy ID 44689)
Length: 2655 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
Pfam ketoacyl-synt 16 264
Pfam Ketoacyl-synt_C 272 397
Pfam KAsynt_C_assoc 399 515
low_complexity n/a 449 454
disorder n/a 454 455
low_complexity n/a 517 528
low_complexity n/a 525 547
Pfam Acyl_transf_1 551 890
low_complexity n/a 778 802
disorder n/a 784 787
low_complexity n/a 890 911
disorder n/a 897 898
Pfam PS-DH 951 1230
disorder n/a 1249 1250
low_complexity n/a 1381 1393
Pfam Methyltransf_12 1441 1555
disorder n/a 1640 1641
low_complexity n/a 1683 1697
disorder n/a 1697 1720
low_complexity n/a 1701 1724
low_complexity n/a 1754 1767
low_complexity n/a 1770 1782
low_complexity n/a 1831 1846
low_complexity n/a 1917 1928
disorder n/a 1928 1929
disorder n/a 1931 1933
low_complexity n/a 2018 2035
Pfam ADH_zinc_N_2 2073 2206
low_complexity n/a 2220 2224
Pfam KR 2247 2431
low_complexity n/a 2269 2280
low_complexity n/a 2589 2604
disorder n/a 2600 2619
low_complexity n/a 2616 2639
coiled_coil n/a 2619 2653
disorder n/a 2624 2655
low_complexity n/a 2643 2655

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q54D44. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MIESQREFNC IGGDNQNGVA VIGVGFKIPL DLENCLSSPS ELYSALFNEF
50
51
DSVTKNTSSR WSDNYFKNGD IVSLSAGLLP LREIKSFDPT FFGINPSDAD
100
101
LIDPQQRLLL KCVWNALEDG GIDPISIRSS DTSVYIGCST IDYFLLNRNP
150
151
VDPHNHGIQT ASYSIPNRIS YCFDFRGESL FVDTACSSSL NAVHLGYNSI
200
201
INLKSKLSIV GGSNLILDPQ NSIFFSKQQV NGPSGKCNSF SEEADGFVRS
250
251
ETVGVVVLKN LKDAIKDGDR IYCVIQGSNS NVDGNYEKLN YISPSKLSQA
300
301
ENITKALKST NGAVNASDID YFECHGTGTP TGDPIELEGI SIALNRTQQS
350
351
TTLSNPLLIG SIKSNIGHGE ASSGIASLIK CCVMFKYRQF LPNINFKTPN
400
401
PLIKFKEWNL KVVTEPVPFN NNKQTIMAIN NFGVSGSNCC IILSEYKSNN
450
451
NNNNDFKATT HLKSKKFIIP FSSNSSTSLD NYKSLLSNET NNFQDFVIKQ
500
501
INNKSTSLIQ RSVIIASNWS EFNESSNEIQ SNIKKSIISN ITIKKKNAVT
550
551
VFVFCGQGSQ YNKMALSLYE NEHIFKSTMD KLDKELSKHY GYSILEKLRS
600
601
ITDEDLVTIH QPILAIPVNV MVQVSLYELY KHWGIKSDIM VGHSFGEIAC
650
651
SYCSGMVDFK TLCYLTYHRS VAQNKTIGSG KMLSINIGAK EYLDSYSTKY
700
701
PSVEIACYNS ETSIVIAGNE ELLNEISKDL KSKDIFTAML PSLSAFHTTH
750
751
QSVIKDDICS LNFKSTLSKI TVFSTVTSNQ FGINNNNNNN NNQLNSNYLF
800
801
QNVIQPVKFS ETISNIYKYI ESNDMGNEIT FIEIAPHPTL QYYLNQMKSQ
850
851
QSEYFNNGEK ISIYSACNKK KNDYNEFLKT ISTLFVNGYN NINFKSQIIN
900
901
NNNNDNNNNF NLPLYQWDDN EYYKIHPTWK KANKNGPSIN HLGNLNDSSI
950
951
KSFKTYINTR KPQFQWLKGH SLKGKVVFPG MGYISNLLSV YNMNQDITIN
1000
1001
EIQFKSAFIL VDGVNNCLET SIVPLTKNEF NIKFHFKDLK TNKWVLCANA
1050
1051
NYSLFKHNDN NDKLDIEKLK SNCNYTIISK DELYNNIRAK SGLIYKGLFQ
1100
1101
GVKEAFIGNR CSLTVLSLNE IENQQEFKHL LENRNFNSLF NTAILDSCLH
1150
1151
GSLHSKEQSQ IYFDKCEGFK YYSNNINLAT SKRNEYKEIN VYIETNPVIN
1200
1201
STVIVSLKIM LPDGTLLIEI QKVVCKSSIP IIDSTSVIQP SPKDLHTPYY
1250
1251
QPKNSLIKPP QSFKHLHCMK EFASIESDNR EMVYMSIYHL IFKAINARSP
1300
1301
TKINLESLEN LTLDQFKELI KDSAANIQRS NQFIYECLKL YHTNHSNYKK
1350
1351
NQIKDFIKEC EDFNGYNQII FKTIKIYAKS LFPLPDDDPF TDTIQSLFED
1400
1401
DQLENVYIHL KHLYPVNNLL SEIVFQSIKP IINQTSTFRI LEIGAGYGTI
1450
1451
SQLIFDKLEQ LLADNFTSSR IDIEYTFTDI SNTFLPRAKE RYSKYKRFNI
1500
1501
IYKLLDLELP LTEGIQDFRP LYYDIVVMSN VLHVVKDINF STNEIYKVLK
1550
1551
QNGQLIFVEP TYKNLYLDTI FGIFPQWWSF NDDIRTDRCC LEPSKWFEFL
1600
1601
ETINFKDTII LGQDNKEILK NVENSIILVQ TRKPSQLELS INNSPSTNQF
1650
1651
KSFENIILYT DDNQQPNDCS EIIDLLKSLE LPIKIINNID QFNQIIKTQY
1700
1701
NNNNNNNNNN NNNNNNNNNN TNNNLIIFLK SVNQLNTNNY KDITFEYVQI
1750
1751
NQILVKLELE ENYKLLLITN NSQSSNYLSN SLIGTSRYLF ADIVSSKLDI
1800
1801
ITIDFDTVSI KNHQNVISVI NHLLDSKDNS EREYYIINNE INIERYKNES
1850
1851
NIKHQLKSKT FQENKDELMV QLDSNLEYRL KSKSKQELKS THVEIQVKAI
1900
1901
GINYKDYATY SGLIDSIIEI DKDKEKDENY DQNYPSIGND FSGVITRIGS
1950
1951
DVRKFKVGDE VCGLAPKTSA SHIITEEGYL CKKPSNISHS EAASSVTVYT
2000
2001
TSFQSIYSIG DLKKNETILI HSGSGGIGLS ALEILKWKNH QGYIFATVGS
2050
2051
EDKVKYLTDT YGSFITGIYS SRDKDYQDQI KEKLKSLGCD IDHQGVDLIL
2100
2101
NTLSVEYMDS NFKCLNQKGR CIDLSITHLT PFDYMDYNKF KFNVSYGNIE
2150
2151
LVVLPSKIIK DHLKKMLKAF SLGSLRFIPI VEFSNLNIRN AVEYINQRKH
2200
2201
IGKIVVKNDV DFINKLFIEQ QQQQNSVENN EILMKDKYDI SNLELGKNIL
2250
2251
LTGQTGIILT ILKWLYKHSN NSIENIIIIS KSKLKWELEL FINESTNNRI
2300
2301
KIHYKQADVG NNNELNQCFE ELRLRHSIED INSIFHFAFI NDIGQFEDVN
2350
2351
MNRMDIAHHA KAIGSLNLHN QSIERKWNIK QFVLASSALS VFGGDNQCCY
2400
2401
ISACSVLDSL SKYRKSIGLP SLSINFGGVT STGFVSRSGA VEANLESSII
2450
2451
NLITPQSLIS SLDLFIQNSQ TFSNYTHFNF IYDNIESYSL NRMLFKFDYL
2500
2501
INQHSSLVSN KRLGGINENN NIGDLLVSKI GELLSIEPSK LNLDFRLVDY
2550
2551
GLDSLVIVQL KNFIDKQFQP HLISILQLQN NKISTTIEII IKGYNNNQNK
2600
2601
KIKNEQSNDI PSVVQKETIK DNNENKDDIK IDMDDKKENL KGKKENIDDK
2650
2651
KENNN                                                 
2655
 

Show the unformatted sequence.

Checksums:
CRC64:E3B1FAE3E3D61146
MD5:d7ee53a9cd40f136d1eb247ddda7365b

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;