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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: DPYD_DICDI (Q55FT1)

Summary

This is the summary of UniProt entry DPYD_DICDI (Q55FT1).

Description: Dihydropyrimidine dehydrogenase [NADP(+)] EC=1.3.1.2
Source organism: Dictyostelium discoideum (Slime mold) (NCBI taxonomy ID 44689)
Length: 1009 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 2
Pfam Fer4_20 53 167
Pfam Pyr_redox_2 186 495
Pfam DHO_dh 530 836
disorder n/a 759 760
disorder n/a 848 852
disorder n/a 856 860
disorder n/a 884 885
disorder n/a 889 905
disorder n/a 907 914
disorder n/a 920 921
Pfam Fer4_21 934 992

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q55FT1. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MTGHTGDVSQ VHDIEILALN PTVNKHATFK PTIVSKKDKE NWARLDHCKK
50
51
GCELKNDFED VKPTTLTERG ALFESARCLK CADAPCQKGC PTQLDIKSFI
100
101
SSISTKNYYG AAKTIFSDNP LGLTCGMVCP VSSLCQYGCN LAATEEGPIN
150
151
IGGLQQFATE VFKKMNIPQI RDPSLTPLSQ LPESYKAKIA LIGCGPTSIS
200
201
CATFLGRLGY TDVTIFEKEQ YLGGLSSSEI PNYRLNYEVV EFEIKLMKDL
250
251
GVKVEYGKRL GENGFTVESL QKQGYEAIYL GIGMPEPKID PVFNELTSDQ
300
301
GFFSSKEFLP KVSKASKAGM CGCKSQLPQL NGRVIVLGAG DTAFDCATSA
350
351
FRCGASRVTV CFRRGFSDMR AVPEEVDIAK DERCEFLPYV LPKQVIKRDG
400
401
KVVAMEFYKT EKGDDGNYSV DEDQFFRVKC DYIISAFGSQ IGSVAESCSP
450
451
LQFNKWGTAD IDPMTMTSKH AEWLFCGGDL VGNGTTVEAV NDGKTASWNI
500
501
HKYLQSLHGI PIPDGPPQLP NFFTPIDLVD ISVEMCGMKF PNPFGLASAT
550
551
PATSAAMIRR SFEQGWGFAV TKTFSLDKDL VTNVSPRIVR GTTSGHHFGP
600
601
GQGAFLNIEL ISEKTCHYWC KAIGELKRDF PDRIVIASIM CGFNKEDWTQ
650
651
LAKMAEASGA DGIELNLSCP HGMGEKGMGL ACGQDTELVF HICQWVRAAT
700
701
RLPFFAKLTP NVTEIKEIAK AAHDGGADGV TAINTVSGLM GLKGDSNAWP
750
751
AIGDEKRTTY GGVSGNATRP IALRAVSSIR KSLPDYPIMA TGGADSADAT
800
801
IQFLHCGASV VQICSSVQNQ DFTVVQDYIT GLKTYLYMQS REDLLQWDGQ
850
851
SPPNEIINKN PKLKGLPKFG KYLLERNRID TEEKQNIDLQ KVKNPLVPSP
900
901
NPTHPVPSLK DQINRAIPRI GRHDDLKRDQ QVVALIDEDK CINCGKCYMT
950
951
CNDSGYQAIK FDGKTHIPLV TDLCTGCDLC LSVCPVPDCI TMVPRETIYV
1000
1001
PDRGLTVQN                                             
1009
 

Show the unformatted sequence.

Checksums:
CRC64:CBC49049106B86B7
MD5:7843e89bf5b9e84848d16f3289102318

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;