Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: AT7L2_HUMAN (Q5T6C5)

Summary

This is the summary of UniProt entry AT7L2_HUMAN (Q5T6C5).

Description: Ataxin-7-like protein 2
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 722 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
low_complexity n/a 1 18
disorder n/a 40 57
disorder n/a 94 98
disorder n/a 100 242
low_complexity n/a 113 121
low_complexity n/a 179 194
Pfam SCA7 224 291
disorder n/a 265 266
disorder n/a 268 321
low_complexity n/a 315 329
disorder n/a 352 404
low_complexity n/a 354 373
low_complexity n/a 382 389
disorder n/a 449 509
low_complexity n/a 468 478
disorder n/a 530 589
low_complexity n/a 541 558
disorder n/a 596 664
disorder n/a 708 712

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q5T6C5. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAVRERAAAA MAALERRVPS LDDFAGQSWS SWVERADLPA ADGAELEESS
50
51
KNTKKLDAMT LIKEDMSIFG HCPAHDDFYL VVCNHCSQVV KPQAFQKHCE
100
101
RRHGPLSKLY GRAPPPPPAP ASSQKCHVVN GQGPACRAPG STKTSSREKG
150
151
QGSRSRGHQP PEKTQKDNLC QPGGLTKDSP GKPPMAPPSK EPPGRENIEI
200
201
IPSEGSSHWA EGSPPEKEPS GTRLPPKTHR KMARKECDLN RQCGVINPET
250
251
KKICTRLLTC KIHSVHQRRE VQGRAKDFDV LVAELKANSR KGESPKEKSP
300
301
GRKEQVLERP SQELPSSVQV VAAVAAPSST FSVRAKQTYP YCALPRSRAS
350
351
SESELDDEGP CGGDGDPGLF PFPMPRGGTQ ASSEESEEEG TSDDLHPPPD
400
401
CHYATRPPRP QAFCTFGSRL VSPGCYVFSR RLDRFCSALS SMLERHLSTH
450
451
MWKKIPPAAE PPAHLVNSPL SAPLSPSSTG TCPRLPGPTL RPACPASMPP
500
501
TKDNLVPSYP AGSPSVAAAC SQAECMGGSQ AITSPLPANT PSPSFSKLPP
550
551
SKASKSSKGK DGVEVEAPSR KRKLSPGPTT LKRTCILEPT GKGKPSGCRG
600
601
LSAKTKTALS MGLNGTMGPR VKRAGPLDCR GSPHQLPTPV KASQLENRGA
650
651
AGHPAKALPT NCLSEEEVAK KRKNLATYCR PVKAKHCQAG APADVACSVR
700
701
RKKPGPALAF EEKCSTLKSK AH                              
722
 

Show the unformatted sequence.

Checksums:
CRC64:EAEF2D380B475A8D
MD5:0b74c9af29278a57f7dcb8fadd160ec8

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;