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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: Q5XI23_RAT (Q5XI23)

Summary

This is the summary of UniProt entry Q5XI23_RAT (Q5XI23).

Description: Probable E3 ubiquitin-protein ligase makorin-2 {ECO:0000256|ARBA:ARBA00019122}
Source organism: Rattus norvegicus (Rat) (NCBI taxonomy ID 10116)
Length: 417 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam zf-CCCH_4 6 27
Pfam zf-CCCH 33 57
disorder n/a 57 153
low_complexity n/a 58 85
disorder n/a 159 160
Pfam zf-CCCH 168 192
Pfam zf-C3HC4 239 292
Pfam zf-CCCH_2 327 349
disorder n/a 357 361
disorder n/a 393 394

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q5XI23. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSTKQVTCRY FMHGVCREGS QCLFSHDLAN SKPSTICKYY QKGYCAYGAR
50
51
CRYDHTKPPA AAGGAVGPAP HPSPSSGLHS PHPSSDIATS VMRTHSNEPR
100
101
KREKKTLVLR DRNLTGLAED KTPPPSTVNN PGGCNDPQTS PEMKPHSYLD
150
151
AIRTGLDDLE ASSSYSNEQQ LCPYAAAGEC RFGDACVYLH GDMCEICRLQ
200
201
VLHPFDPEQR KAHEKMCMST FEHEMEKAFA FQASQDKVCS ICMEVILEKA
250
251
SASERRFGIL SNCSHTYCLS CIRQWRCAKQ FENPIIKSCP ECRVISEFVI
300
301
PSVYWVEDQN KKNELIEAFK QGMGKKACKY FEQGKGTCPF GSKCLYRHAY
350
351
PDGRLAEPEK PRKQLSSEGT VRFFNSVRLW DFIENRETRQ VPSTDDVDVT
400
401
ELGDLFMHLS GVESSEP                                    
417
 

Show the unformatted sequence.

Checksums:
CRC64:0C0C8B6D1B9155BA
MD5:0358813acb504fc09432c388acae937c

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;