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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ATX1_RAT (Q63540)

Summary

This is the summary of UniProt entry ATX1_RAT (Q63540).

Description: Ataxin-1
Source organism: Rattus norvegicus (Rat) (NCBI taxonomy ID 10116)
Length: 789 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam ATXN-1_C 1 532
disorder n/a 1 118
low_complexity n/a 49 67
disorder n/a 140 147
disorder n/a 149 182
low_complexity n/a 153 168
disorder n/a 184 263
disorder n/a 266 415
disorder n/a 467 470
disorder n/a 476 480
low_complexity n/a 529 542
Pfam AXH 548 661
disorder n/a 668 670
disorder n/a 675 678
disorder n/a 680 685
disorder n/a 692 706
disorder n/a 708 712
disorder n/a 731 773

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q63540. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKSNQERSNE CLPPKKREIP ATSRPSEEKA TALPSDNHCV EGVAWLPSTP
50
51
GSRGHGGGRH GPAGTSGEHG LQGMGLHKAL SAGLDYSPPS APRSVPTANT
100
101
LPTVYPPPQS GTPVSPVQYA HLSHTFQFIG SSQYSGPYAG FIPSQLISPP
150
151
GNPVTSAVAS AAGATTPSQR SQLEAYSTLL ANMGSLSQAP GHKVEPPPQQ
200
201
HLGRAAGLVN PGSPPPTQQN QYIHISSSPQ SSGRATSPPI PVHLHPHQTM
250
251
IPHTLTLGPS SQVVVQYSDA GGHFVPREST KKAESSRLQQ AMQAKEVLNG
300
301
EMEKSRRYGA SSSVELSLGK TSSKSVPHPY ESRHVVVHPS PADYSSRDTS
350
351
GVRGSVMVLP NSSTPSADLE TQQATHREAS PSTLNDKSGL HLGKPGHRSY
400
401
ALSPHTVIQT THSASEPLPV GLPATAFYAG AQPPVIGYLS SQQQAITYAG
450
451
GLPQHLVIPG TQPLLIPVGS PDMDTPGAAS AIVTSSPQFA AVPHTFVTTA
500
501
LPKSENFNPE ALVTQAAYPA MVQAQIHLPV VQSVASPAAA SPTLPPYFMK
550
551
GSIIQLANGE LKKVEDLKTE DFIQSAEISN DLKIDSSTVE RIEDSHSPGV
600
601
AVIQFAVGEH RAQVSVEVLV EYPFFVFGQG WSSCCPERTS QLFDLPCSKL
650
651
SVGDVCISLT LKNLKNGSVK KGQPVDPASA LLKHAKTDSL AGSRHRYAEQ
700
701
ENGINQGSAQ VLSENGELKF PEKIGLPAAP FLTKIEPSKP TATRKRRWSA
750
751
PETRKLEKSE DEPPLTLPKP SLIPQEVKIC IEGRSNVGK            
789
 

Show the unformatted sequence.

Checksums:
CRC64:AFA042249BAC99FE
MD5:0944b39c0852089d488598e76b41ae5d

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;