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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PDE1C_MOUSE (Q64338)

Summary

This is the summary of UniProt entry PDE1C_MOUSE (Q64338).

Description: Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
Length: 706 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 7
disorder n/a 10 14
coiled_coil n/a 34 64
Pfam PDEase_I_N 82 142
Pfam PDEase_I 227 456
disorder n/a 452 498
disorder n/a 517 706
coiled_coil n/a 518 553
low_complexity n/a 523 549
low_complexity n/a 542 558
low_complexity n/a 662 672

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q64338. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MESPTKEIEE FESNSLKHLQ PEQIEKIWLR LRGLRKYKKT SQRLRSLVKQ
50
51
LERGEASVVD LKKNLEYAAT VLESVYIDET RRLLDTEDEL SDIQSDAVPS
100
101
EVRDWLASTF TRQMGMMLRR SDEKPRFKSI VHAVQAGIFV ERMYRRTSNM
150
151
VGLSYPPAVI DALKDVDTWS FDVFSLNEAS GDHALKFIFY ELLTRYDLIS
200
201
RFKIPISALV SFVEALEVGY SKHKNPYHNL MHAADVTQTV HYLLYKTGVA
250
251
NWLTELEIFA IIFSAAIHDY EHTGTTNNFH IQTRSDPAIL YNDRSVLENH
300
301
HLSAAYRLLQ EDEEMNILVN LSKDDWREFR TLVIEMVMAT DMSCHFQQIK
350
351
AMKTALQQPE AIEKPKALSL MLHTADISHP AKAWDLHHRW TMSLLEEFFR
400
401
QGDREAELGL PFSPLCDRKS TMVAQSQVGF IDFIVEPTFT VLTDMTEKIV
450
451
SPLIDESSQT GGTGQRRSSL NSINSSDAKR SGVKSSGSDG SAPINNSVIP
500
501
VDYKSFKATW TEVVQINRER WRAKVPKEEK AKKEAEEKAR LAAEEKQKEM
550
551
EAKSQAEQGT TSKGEKKTSG EAKSQVNGTR KGDNPRGKNS KGEKAGEKQQ
600
601
NGDLKDGKNK ADKKDHSNTG NESKKTDGTK KRSHGSPAPS TSSTSRITLP
650
651
VIKPPLRHFK RPAYASSSYA PSVPKKTDDH PVRYKMLDQR IKMKKIQNIS
700
701
HHWNKK                                                
706
 

Show the unformatted sequence.

Checksums:
CRC64:1F58533E1259801F
MD5:a2de131245d3ccaec09382c75918608e

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;