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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: SARM1_DROME (Q6IDD9)

Summary

This is the summary of UniProt entry SARM1_DROME (Q6IDD9).

Description: NAD(+) hydrolase sarm1 {ECO:0000305}
Source organism: Drosophila melanogaster (Fruit fly) (NCBI taxonomy ID 7227)
Length: 1360 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 5 8
disorder n/a 10 11
disorder n/a 15 76
low_complexity n/a 28 48
disorder n/a 86 87
disorder n/a 90 91
disorder n/a 98 100
disorder n/a 102 111
disorder n/a 113 126
disorder n/a 128 136
low_complexity n/a 128 140
disorder n/a 144 150
disorder n/a 157 209
disorder n/a 217 219
disorder n/a 226 227
disorder n/a 231 234
disorder n/a 237 241
disorder n/a 246 301
low_complexity n/a 254 264
low_complexity n/a 290 304
low_complexity n/a 311 324
disorder n/a 358 362
Pfam SAM_2 687 752
coiled_coil n/a 741 761
Pfam SAM_2 757 824
low_complexity n/a 822 834
Pfam TIR_2 841 974
disorder n/a 989 990
disorder n/a 994 1029
low_complexity n/a 1011 1035
disorder n/a 1032 1036
disorder n/a 1038 1043
disorder n/a 1045 1102
disorder n/a 1105 1360
low_complexity n/a 1119 1141
low_complexity n/a 1158 1162
low_complexity n/a 1165 1179
low_complexity n/a 1321 1335

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q6IDD9. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKAAEIKRDL TNIQKSMSEI NDLAKERITG GPGSISTTSA SAITAPSTMS
50
51
QTTTSRLAPK LTSAHPSIDD LRGLSRQDKI TQLQKKIRAS FENLVDHDDS
100
101
NVIVTLPDDD DCPHNHFGSG LNLTHPTAAQ LSASGLSGSS KTIDTIKFQE
150
151
KSMKTESKTK VVTDGFSSEQ ATSNSAEMKR LQAGDIDYQE SKGASAMRNR
200
201
LEVDGVKTEE NAAVIKEALS LRTGDITQQA SNNVAASSIT VQSENFSADK
250
251
KAISQSQQSQ TMTSNGIISQ EKHVSSASQA NYSMSHKGVS STGSSMITSS
300
301
SQMSAMNGQM LKLADLKLDD LKSLTAGSGQ QEIEQTINKY SNMLTSIVSS
350
351
LQEDERGGSA ITVHDVGGKK SQYLEKINEV IRRAWAVPTH GHELGYSLCN
400
401
SLRQSGGLDL LMKNCVKPDL QFSSAQLLEQ CLTTENRKHV VDNGLDKVVN
450
451
VACVCTKNSN MEHSRVGTGI LEHLFKHSEG TCSDVIRLGG LDAVLFECRT
500
501
SDLETLRHCA SALANLSLYG GAENQEEMIL RKVPMWLFPL AFHNDDNIKY
550
551
YACLAIAVLV ANKEIEAEVL KSGCLDLVEP FVTSHDPSAF ARSNLAHAHG
600
601
QSKHWLKRLV PVLSSNREEA RNLAAFHFCM EAGIKREQGN TDIFREINAI
650
651
EALKNVASCP NAIASKFAAQ ALRLIGETVP HKLSQQVPLW SVEDVQEWVK
700
701
QIGFNDYIDK FNESQVDGDL LLKLNQDNLR ADIGIGNGIL LKRFERELQN
750
751
LKRMADYSSK DTAKMHQFLS EIGTDYCTYT YAMLNAGIDK CALPHVNEDM
800
801
LMTECGIHNS IHRLRILNAV KNLENSLPSS SEENMAKTLD VFVSYRRSNG
850
851
SQLASLLKVH LQLRGFSVFI DVERLEAGKF DNGLLNSIRQ AKNFVLVLTP
900
901
DALHRCINDE DCKDWVHREI VAALNSNCNI IPIIDQQFDW PEVERLPEDM
950
951
RSVAHFNGVN WIHDYQDACI DKLERFLRGE KNIDRIAAMV PGTPGSVSYQ
1000
1001
RMHSNDSDYQ SGGAGAGSGA GTGGGGGGGV TGSVVDGLMV AANGSGQANH
1050
1051
QANRYRQSPS PARQRGSTSQ LSGYSRAPSK RSQILTPYRT QQAALLHKTG
1100
1101
AGSASMQNMM PLAYLPPRRS SAAGLGHGSG SGMGSGYRSH SVDGLLDQAG
1150
1151
STPEQRIAAA AAKVTAGSTA LTNASSTSTL QPEEEVTDAA LNDSVTRRDK
1200
1201
HTLSPPGNVQ QHRKSRSLDH ILSKQTLAEL LPPSSELADG TQSMQNLAIP
1250
1251
MTPQPQRRDT SSSSKSPTPE RPPQPAMERV RERQSPEGVS ATESEREDQP
1300
1301
EECLRHGNQQ RASASVHRGA SLTSNKTSNS SLGSNFSAGG NNKTIFNRTM
1350
1351
KKVRSLIKKP                                            
1360
 

Show the unformatted sequence.

Checksums:
CRC64:F3838F5AF4FE934D
MD5:28b51a6e9d0b183c4a506b5ab05cfb90

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;