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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: IFIX_HUMAN (Q6K0P9)

Summary

This is the summary of UniProt entry IFIX_HUMAN (Q6K0P9).

Description: Pyrin and HIN domain-containing protein 1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 492 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam PYRIN 8 80
disorder n/a 100 101
disorder n/a 104 107
disorder n/a 109 207
low_complexity n/a 176 194
Pfam HIN 211 379
disorder n/a 236 240
low_complexity n/a 256 279
disorder n/a 357 360
low_complexity n/a 371 382
disorder n/a 388 492
low_complexity n/a 438 452

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q6K0P9. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MANNYKKIVL LKGLEVINDY HFRIVKSLLS NDLKLNPKMK EEYDKIQIAD
50
51
LMEEKFPGDA GLGKLIEFFK EIPTLGDLAE TLKREKLKVA NKIESIPVKG
100
101
IIPSKKTKQK EVYPATPACT PSNRLTAKGA EETLGPQKRK KPSEEETGTK
150
151
RSKMSKEQTR PSCSAGASTS TAMGRSPPPQ TSSSAPPNTS STESLKPLAN
200
201
RHATASKNIF REDPIIAMVL NATKVFKYES SENEQRRMFH ATVATQTQFF
250
251
HVKVLNINLK RKFIKKRIII ISNYSKRNSL LEVNEASSVS EAGPDQTFEV
300
301
PKDIIRRAKK IPKINILHKQ TSGYIVYGLF MLHTKIVNRK TTIYEIQDKT
350
351
GSMAVVGKGE CHNIPCEKGD KLRLFCFRLR KRENMSKLMS EMHSFIQIQK
400
401
NTNQRSHDSR SMALPQEQSQ HPKPSEASTT LPESHLKTPQ MPPTTPSSSS
450
451
FTKKDETHPG AQSSPANFRI TSPTVAPPLS SDTSTNRHPA VP        
492
 

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Checksums:
CRC64:8711AABB92477D10
MD5:05cd925392a6609dfff436279549bafb

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.