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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ORAI3_MOUSE (Q6P8G8)

Summary

This is the summary of UniProt entry ORAI3_MOUSE (Q6P8G8).

Description: Protein orai-3
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
Length: 290 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 18
Pfam Orai-1 46 271
transmembrane n/a 63 82
transmembrane n/a 94 120
transmembrane n/a 149 172
disorder n/a 213 228
transmembrane n/a 240 262
disorder n/a 273 282

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q6P8G8. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKGGEGDTGE QAPLNPEVDS PAGSATYREF VHRGYLDLMG ASQHSLRALS
50
51
WRRLYLSRAK LKASSRTSAL LSGFAMVAMV EVQLENDHEY PPGLLVAFSA
100
101
CTTVLVAVHL FALMVSTCLL PHIEAVSNIH NLNSVHQSPH QRLHRYVELA
150
151
WGFSTALGTF LFLAEVVLVG WVKFVPIGAP MGKPAPVVPM SQVPPVTVSL
200
201
SLASNLTPSS ASITTSQQPS KACPPRQVCD SAHGPGWQAA MASTAIMVPV
250
251
GLVFMAFALH FYRSLVAHKT DRHKQELEEL SRLQGELQAV           
290
 

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Checksums:
CRC64:F702164F9F1EB44B
MD5:b69fb98b256c16925f8f21111b9679e6

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;