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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ZN549_HUMAN (Q6P9A3)

Summary

This is the summary of UniProt entry ZN549_HUMAN (Q6P9A3).

Description: Zinc finger protein 549
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 640 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam KRAB 26 67
disorder n/a 79 91
disorder n/a 151 161
disorder n/a 208 212
disorder n/a 238 248
Pfam zf-C2H2 275 298
disorder n/a 291 292
Pfam zf-C2H2 304 326
Pfam zf-C2H2 332 355
disorder n/a 348 349
Pfam zf-C2H2 361 383
Pfam zf-C2H2 389 411
Pfam zf-C2H2 417 439
Pfam zf-C2H2 445 467
Pfam zf-C2H2 473 495
Pfam zf-C2H2 529 551
Pfam zf-C2H2 557 579
Pfam zf-C2H2 613 635
disorder n/a 637 640

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q6P9A3. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAEAALVITP QIPMVTEEFV KPSQGHVTFE DIAVYFSQEE WGLLDEAQRC
50
51
LYHDVMLENF SLMASVGCLH GIEAEEAPSE QTLSAQGVSQ ARTPKLGPSI
100
101
PNAHSCEMCI LVMKDILYLS EHQGTLPWQK PYTSVASGKW FSFGSNLQQH
150
151
QNQDSGEKHI RKEESSALLL NSCKIPLSDN LFPCKDVEKD FPTILGLLQH
200
201
QTTHSRQEYA HRSRETFQQR RYKCEQVFNE KVHVTEHQRV HTGEKAYKRR
250
251
EYGKSLNSKY LFVEHQRTHN AEKPYVCNIC GKSFLHKQTL VGHQQRIHTR
300
301
ERSYVCIECG KSLSSKYSLV EHQRTHNGEK PYVCNVCGKS FRHKQTFVGH
350
351
QQRIHTGERP YVCMECGKSF IHSYDRIRHQ RVHTGEGAYQ CSECGKSFIY
400
401
KQSLLDHHRI HTGERPYECK ECGKAFIHKK RLLEHQRIHT GEKPYVCIIC
450
451
GKSFIRSSDY MRHQRIHTGE RAYECSDCGK AFISKQTLLK HHKIHTRERP
500
501
YECSECGKGF YLEVKLLQHQ RIHTREQLCE CNECGKVFSH QKRLLEHQKV
550
551
HTGEKPCECS ECGKCFRHRT SLIQHQKVHS GERPYNCTAC EKAFIYKNKL
600
601
VEHQRIHTGE KPYECGKCGK AFNKRYSLVR HQKVHITEEP           
640
 

Show the unformatted sequence.

Checksums:
CRC64:CED338B5CC75DD97
MD5:784a4aeb1fcca585c0d1b19e875285d9

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;