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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: SCNAA_MOUSE (Q6QIY3)

Summary

This is the summary of UniProt entry SCNAA_MOUSE (Q6QIY3).

Description: Sodium channel protein type 10 subunit alpha
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
Length: 1958 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 32 54
transmembrane n/a 128 146
Pfam Ion_trans 129 406
transmembrane n/a 158 177
transmembrane n/a 189 210
transmembrane n/a 222 243
transmembrane n/a 249 268
transmembrane n/a 333 352
transmembrane n/a 372 395
low_complexity n/a 405 420
coiled_coil n/a 407 430
disorder n/a 445 492
disorder n/a 499 508
disorder n/a 517 526
disorder n/a 530 583
low_complexity n/a 557 572
transmembrane n/a 660 683
Pfam Ion_trans 663 898
transmembrane n/a 695 717
transmembrane n/a 783 803
low_complexity n/a 791 803
transmembrane n/a 834 851
transmembrane n/a 863 889
low_complexity n/a 870 883
low_complexity n/a 878 894
Pfam Na_trans_assoc 903 1148
disorder n/a 972 995
disorder n/a 999 1097
coiled_coil n/a 1000 1020
low_complexity n/a 1002 1015
disorder n/a 1101 1104
low_complexity n/a 1103 1114
Pfam Ion_trans 1152 1430
transmembrane n/a 1154 1172
transmembrane n/a 1193 1209
transmembrane n/a 1221 1240
low_complexity n/a 1249 1264
transmembrane n/a 1261 1279
transmembrane n/a 1285 1305
transmembrane n/a 1358 1376
transmembrane n/a 1396 1419
low_complexity n/a 1399 1409
transmembrane n/a 1469 1492
Pfam Ion_trans 1476 1734
transmembrane n/a 1512 1530
transmembrane n/a 1542 1561
low_complexity n/a 1549 1566
transmembrane n/a 1567 1585
low_complexity n/a 1572 1591
transmembrane n/a 1597 1625
disorder n/a 1679 1686
transmembrane n/a 1700 1723
disorder n/a 1877 1886
disorder n/a 1891 1894
disorder n/a 1899 1958

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q6QIY3. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEFPFGSVGT TNFRRFTPES LAEIEKQIAA HRAAKKGRPK QRGQKDKSEK
50
51
PRPQLDLKAC NQLPRFYGEL PAELVGEPLE DLDPFYSTHR TFIVLDKSRT
100
101
ISRFSATWAL WLFSPFNLIR RTAIKVSVHS WFSIFITVTI LVNCVCMTRT
150
151
DLPEKLEYAF TVVYTFEALI KILARGFCLN EFTYLRDPWN WLDFSVITLA
200
201
YVGAAIDLRG ISGLRTFRVL RALKTVSVIP GLKVIVGALI HSVRKLADVT
250
251
ILTVFCLSVF ALVGLQLFKG NLKNKCIKNG TDPHKADNLS SEMAGDIFIK
300
301
PGTTDPLLCG NGSDAGHCPN DYVCRKTSDN PDFNYTSFDS FAWAFLSLFR
350
351
LMTQDSWERL YQQTLRASGK MYMVFFVLVI FLGSFYLVNL ILAVVTMAYE
400
401
EQSQATIAEI EAKEKKFKEA LEVLQKEQEV LAALGIDTTS LYSHNGSPLA
450
451
PKNANERRPR VKSRMSEGST DDNRSLQSDP YNQRRMSFLG LSSGRRRASH
500
501
SSVFHFRAPS QDVSFPDGIL DDGVFHGDQE SRRSSILLGR GAGQAGPLPR
550
551
SPLPQSPNPG PRRGEEGQRG VPTGELATGA PEGPALDAAG QKNFLSADYL
600
601
NEPFRAQRAM SVVSIMTSVI EELEESKLKC PPCLISLAQK YLIWECCPKW
650
651
KKFKMVLFEL VTDPFAELTI TLCIVVNTVF MAMEHYPMTD AFDAMLQAGN
700
701
IVFTVFFTME MAFKIIAFDP YYYFQKKWNI FDCVIVTVSL LELSTSKKGS
750
751
LSVLRTFRLL RVFKLAKSWP TLNMLIKIIG NSVGALGNLT FILAIIVFIF
800
801
ALVGKQLLSE NYGCRRDGIS VWNGERLRWH MCDFFHSFLV VFRILCGEWI
850
851
ENMWVCMEVS QDYICLTLFL TVMVLGNLVV LNLFIALLLN SFSADNLTAP
900
901
EDDGEVNNLQ VALARIQVFG HRASRAITSY IRSHCRLRWP KVETQLGMKP
950
951
PLTSCKAENH IATDAVNAAV GNLAKPALGG PKENHGDFIT DPNVWVSVPI
1000
1001
AEGESDLDEL EEDVEHASQS SWQEESPKGQ QELLQQVQKC EDHQAARSPP
1050
1051
SGMSSEDLAP YLGERWQREE SPRVPAEGVD DTSSSEGSTV DCPDPEEILR
1100
1101
KIPELAEELD EPDDCFPEGC TRRCPCCKVN TSKFPWATGW QVRKTCYRIV
1150
1151
EHSWFESFII FMILLSSGAL AFEDNYLEEK PRVKSVLEYT DRVFTFIFVF
1200
1201
EMLLKWVAYG FKKYFTNAWC WLDFLIVNIS LTSLIAKILE YSDVASIKAL
1250
1251
RTLRALRPLR ALSRFEGMRV VVDALVGAIP SIMNVLLVCL IFWLIFSIMG
1300
1301
VNLFAGKFSR CVDTRSNPFS VVNSTFVTNK SDCYNQNNTG HFFWVNVKVN
1350
1351
FDNVAMGYLA LLQVATFKGW MDIMYAAVDS RDINSQPNWE ESLYMYLYFV
1400
1401
VFIIFGGFFT LNLFVGVIID NFNQQKKKLG GQDIFMTEEQ KKYYNAMKKL
1450
1451
GSKKPQKPIP RPLNKYQGFV FDIVTRQAFD IIIMALICLN MITMMVETDN
1500
1501
QSEEKTKVLG RINQFFVAVF TGECVMKMFA LRQYYFTNGW NVFDFIVVIL
1550
1551
SISSLLFSAI LSSLESYFSP TLLRVIRLAR IGRILRLIRA AKGIRTLLFA
1600
1601
LMMSLPALFN IGLLLFLVMF IYSIFGMASF ANVIDEAGID DMFNFKTFGN
1650
1651
SMLCLFQITT SAGWDGLLSP ILNTGPPYCD PNRPNSNGSK GNCGSPAVGI
1700
1701
LFFTTYIIIS FLIVVNMYIA VILENFNVAT EESTEPLSED DFDMFYETWE
1750
1751
KFDPEATQFI AFSALSDFAD TLSGPLRIPK PNQNILIQMD LPLVPGDKIH
1800
1801
CLDILFAFTK NVLGESGELD SLKTNMEEKF MATNLSKASY EPIATTLRCK
1850
1851
QEDISATIIQ KAYRNYMLQR SLMLSNPLHV PRAEEDGVSL PREGYVTFMA
1900
1901
NDNGGLPDKS ETASATSFPP SYDSVTRGLS DRANISTSSS MQNEDEVTAK
1950
1951
EGKSPGPQ                                              
1958
 

Show the unformatted sequence.

Checksums:
CRC64:24830634E86490FF
MD5:3e22305d98312140b66641e44a9394cd

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;