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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: TLR11_MOUSE (Q6R5P0)

Summary

This is the summary of UniProt entry TLR11_MOUSE (Q6R5P0).

Description: Toll-like receptor 11 {ECO:0000303|PubMed:14993594}
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
Length: 926 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
sig_p n/a 1 30
low_complexity n/a 11 26
low_complexity n/a 105 122
low_complexity n/a 153 161
Pfam LRR_8 361 421
low_complexity n/a 381 393
low_complexity n/a 544 556
transmembrane n/a 722 741
low_complexity n/a 730 741
Pfam TIR_2 776 915
low_complexity n/a 869 882
disorder n/a 922 923
disorder n/a 925 926

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q6R5P0. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MPRMERHQFC SVLLILILLT LVSLTLTGWA WTIPDCIIAD SLLFPNLSYY
50
51
IPFCTSAPGL HLLASCSNVK NLNQTLKRVP RNTEVLCLQG MVPTLPAKAF
100
101
IRFHSLQLLR LQLRTTSVTS RTFQGLDQLQ YLFFDHHAPC CLSLFLSPNC
150
151
FESLRSLSSL SFQGYCLTYS QSIYLPTSLR HLTLRNSCLT KFQDLQRLFP
200
201
DLLLSTSSTP NIKPGAPFLE TLDLSYNLQL KQAGVRDLYG LTLHSLILDG
250
251
TPLKALDLTD SGLLHLHFLS LVGTGIEKVP ASLTGYSELR ALDLGKNQIQ
300
301
NILENGEIPG YKALEFLSLH DNHLQTLPTR FLHTLPQLQK LNLSMNKLGP
350
351
ILELPEGLFS TNLKVLDLSY NQLCDVPHGA LSLLSQLQEL WLSGNNISSL
400
401
SNESLQGLRQ LRTLDLSWNQ IKVLKPGWLS HLPALTTLNL LGTYLEYILG
450
451
IQLQGPKMLR HLQLGSYPIL DIYPPWPPTL LSLEIQAESC IQFMIHSGQP
500
501
FLFLENLTLE TSILLLKPDN ITIHFPSLRR LTLRGYSFIF STSQLQRFFP
550
551
QQLPLLEHFF IWCENSYAVD LYLFGMPRLR VLELGYLNFF YESSTMKLEM
600
601
LLKEVPQLQV LALSHLNLRN LSVSSFKSLQ DLKLLLFNSE RALEMNSNLQ
650
651
EFIPQMPQYV YFSDVTFTCQ CEASWLESWA TRAPNTFVYG LEKSICIANA
700
701
SDYSKTLLFS FLATNCPHGT EFWGFLTSFI LLLLLIILPL ISCPKWSWLH
750
751
HLWTLFHTCW WKLCGHRLRG QFNYDVFISY CEEDQAWVLE ELVPVLEKAP
800
801
PEGEGLRLCL PARDFGIGND RMESMIASMG KSRATLCVLT GQALASPWCN
850
851
LELRLATYHL VARPGTTHLL LLFLEPLDRQ RLHSYHRLSR WLQKEDYFDL
900
901
SQGKVEWNSF CEQLKRRLSK AGQERD                          
926
 

Show the unformatted sequence.

Checksums:
CRC64:DF86FED308671285
MD5:8223292b0fd617181247cbad40c598db

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;