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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: S4A5_RAT (Q6RI88)

Summary

This is the summary of UniProt entry S4A5_RAT (Q6RI88).

Description: Electrogenic sodium bicarbonate cotransporter 4
Source organism: Rattus norvegicus (Rat) (NCBI taxonomy ID 10116)
Length: 1112 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 2 47
disorder n/a 49 77
disorder n/a 80 81
disorder n/a 94 122
Pfam Band_3_cyto 140 407
disorder n/a 148 149
disorder n/a 210 211
disorder n/a 222 258
disorder n/a 271 296
disorder n/a 408 414
low_complexity n/a 436 465
disorder n/a 439 470
Pfam HCO3_cotransp 485 999
transmembrane n/a 514 536
transmembrane n/a 548 579
transmembrane n/a 599 620
transmembrane n/a 632 655
transmembrane n/a 735 753
transmembrane n/a 773 792
transmembrane n/a 821 839
transmembrane n/a 859 875
transmembrane n/a 881 900
transmembrane n/a 921 940
transmembrane n/a 946 966
transmembrane n/a 993 1010
transmembrane n/a 1016 1033
low_complexity n/a 1051 1065
disorder n/a 1055 1070

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q6RI88. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKVEEKAGVK KLEPTSYRRR HPEQDFPSIH IGFPVPGYSQ RKSDSKGHLS
50
51
GLQRVQWSLQ PDKSQQDLAG PDGIKASSLG GSVDFTKRIR SPAAEQLQDI
100
101
LGEEDEAPNP TLFTEMDTLQ HDGDQMEWKE SARWIKFEEK VEEGGERWSK
150
151
PHVSTLSLHS LFELRTCLQT GTVLLDLDSG SLPQIIDDVI EKQIEGGLLR
200
201
PELRERVSYV LLRKHRHQTK KPIHRSLADI GKSVSTTNRS SARSPSAGPT
250
251
LHHSTEDLRI RQSTSYGHLC HAQSRSMNDI SHTPNTDQRK NKFMKKIPKD
300
301
SEASNVLVGE VDFLDQPFIA FVRLAQSSML GGVTEVPVPT RFLFILLGPS
350
351
GRAKSYNEIG RAIATLMVDD LFSDVAYKAR NREDLIAGVD EFLDEVIVLP
400
401
PGEWDPNIRI EPPKKVPSAD KRKSVFSLAE LGQMNGSVGR SGASAGGGGS
450
451
GGGAGGSGAG GGGSGNEAEM PAMHEIGEEL IWTGRFFGGL RLDVKRKLPW
500
501
FPSDFYDGFH IQSISAVLFI YLGCITNAIT FGGLLGDATD NYQGVMESFL
550
551
GTAMAGSLFC LFSGQPLIIL SSTGPILIFE KLLFDFSKAN GLDYMEFRLW
600
601
IGLHSAIQCL ILVATDASFI IKYITRFTEE GFSTLISFIF IYDAIKKMIG
650
651
AFKYYPINTD FKPDSITTYK CECVAPDTVN TTTVNDSALL VPNTNMSVYT
700
701
PLNLTALDWS LLSKKECLSY GGRLLGSSCQ FVPDLALMSF ILFFGTYSMT
750
751
LTLKKFKFSR YFPTKVRTLV ADFSIVFSIL LFCGIDACFG LQTPKLHVPN
800
801
VIKPTRPDRG WFVAPFGKNP WWVYPASILP ALLVTILIFM DQQITAVIVN
850
851
RKENKLRKAA GYHLDLFWVG ILMALCSFMG LPWYVAATVI SIAHIDSLKM
900
901
ETETSAPGEQ PQFLGVREQR VTGVMVFILT GISVFLAPIL KYIPMPVLYG
950
951
VFLYMGVASL NGIQFWDRCK LFLMPAKHQP DHAFLRHVPL RRIHLFTLVQ
1000
1001
ILCLALLWIL KSTMAAIIFP VMILGLIIVR RLLDLIFSQH DLAWIDNILP
1050
1051
EKEKKESDRK KRRKEVHENT DKEPQFLPPS VVKIPMEGIP SDPQNGIHCV
1100
1101
GRKRSSSWSH SL                                         
1112
 

Show the unformatted sequence.

Checksums:
CRC64:BE5EF90A543DA35C
MD5:f1b9b39a2794b2206af3073ed6ba614a

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;