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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ASXL2_HUMAN (Q76L83)

Summary

This is the summary of UniProt entry ASXL2_HUMAN (Q76L83).

Description: Putative Polycomb group protein ASXL2
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 1435 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 43
Pfam HARE-HTH 11 83
disorder n/a 48 60
disorder n/a 66 71
disorder n/a 82 233
low_complexity n/a 95 129
low_complexity n/a 127 139
low_complexity n/a 136 147
low_complexity n/a 158 181
coiled_coil n/a 163 183
low_complexity n/a 227 235
disorder n/a 249 259
Pfam ASXH 256 380
disorder n/a 261 267
disorder n/a 317 319
disorder n/a 343 344
disorder n/a 350 357
disorder n/a 359 361
disorder n/a 387 415
disorder n/a 431 470
disorder n/a 475 1029
low_complexity n/a 672 684
low_complexity n/a 687 713
low_complexity n/a 771 785
low_complexity n/a 883 896
low_complexity n/a 905 925
disorder n/a 1031 1032
disorder n/a 1035 1037
disorder n/a 1040 1042
disorder n/a 1049 1058
disorder n/a 1093 1094
disorder n/a 1107 1109
disorder n/a 1111 1113
disorder n/a 1121 1126
disorder n/a 1135 1140
disorder n/a 1142 1147
disorder n/a 1149 1151
disorder n/a 1162 1238
low_complexity n/a 1170 1192
disorder n/a 1242 1244
disorder n/a 1246 1250
disorder n/a 1253 1254
disorder n/a 1260 1270
disorder n/a 1272 1282
disorder n/a 1288 1296
disorder n/a 1299 1315
low_complexity n/a 1301 1316
disorder n/a 1318 1319
disorder n/a 1328 1332
disorder n/a 1334 1348
disorder n/a 1371 1375
Pfam PHD_3 1373 1433
disorder n/a 1378 1388

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q76L83. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MREKGRRKKG RTWAEAAKTV LEKYPNTPMS HKEILQVIQR EGLKEIRSGT
50
51
SPLACLNAML HTNSRGEEGI FYKVPGRMGV YTLKKDVPDG VKELSEGSEE
100
101
SSDGQSDSQS SENSSSSSDG GSNKEGKKSR WKRKVSSSSP QSGCPSPTIP
150
151
AGKVISPSQK HSKKALKQAL KQQQQKKQQQ QCRPSISISS NQHLSLKTVK
200
201
AASDSVPAKP ATWEGKQSDG QTGSPQNSNS SFSSSVKVEN TLLGLGKKSF
250
251
QRSERLHTRQ MKRTKCADID VETPDSILVN TNLRALINKH TFSVLPGDCQ
300
301
QRLLLLLPEV DRQVGPDGLM KLNGSALNNE FFTSAAQGWK ERLSEGEFTP
350
351
EMQVRIRQEI EKEKKVEPWK EQFFESYYGQ SSGLSLEDSK KLTASPSDPK
400
401
VKKTPAEQPK SMPVSEASLI RIVPVVSQSE CKEEALQMSS PGRKEECESQ
450
451
GEVQPNFSTS SEPLLSSALN THELSSILPI KCPKDEDLLE QKPVTSAEQE
500
501
SEKNHLTTAS NYNKSESQES LVTSPSKPKS PGVEKPIVKP TAGAGPQETN
550
551
MKEPLATLVD QSPESLKRKS SLTQEEAPVS WEKRPRVTEN RQHQQPFQVS
600
601
PQPFLNRGDR IQVRKVPPLK IPVSRISPMP FHPSQVSPRA RFPVSITSPN
650
651
RTGARTLADI KAKAQLVKAQ RAAAAAAAAA AAAASVGGTI PGPGPGGGQG
700
701
PGEGGEGQTA RGGSPGSDRV SETGKGPTLE LAGTGSRGGT RELLPCGPET
750
751
QPQSETKTTP SQAQPHSVSG AQLQQTPPVP PTPAVSGACT SVPSPAHIEK
800
801
LDNEKLNPTR ATATVASVSH PQGPSSCRQE KAPSPTGPAL ISGASPVHCA
850
851
ADGTVELKAG PSKNIPNPSA SSKTDASVPV AVTPSPLTSL LTTATLEKLP
900
901
VPQVSATTAP AGSAPPSSTL PAASSLKTPG TSLNMNGPTL RPTSSIPANN
950
951
PLVTQLLQGK DVPMEQILPK PLTKVEMKTV PLTAKEERGM GALIATNTTE
1000
1001
NSTREEVNER QSHPATQQQL GKTLQSKQLP QVPRPLQLFS AKELRDSSID
1050
1051
THQYHEGLSK ATQDQILQTL IQRVRRQNLL SVVPPSQFNF AHSGFQLEDI
1100
1101
STSQRFMLGF AGRRTSKPAM AGHYLLNIST YGRGSESFRR THSVNPEDRF
1150
1151
CLSSPTEALK MGYTDCKNAT GESSSSKEDD TDEESTGDEQ ESVTVKEEPQ
1200
1201
VSQSAGKGDT SSGPHSRETL STSDCLASKN VKAEIPLNEQ TTLSKENYLF
1250
1251
TRGQTFDEKT LARDLIQAAQ KQMAHAVRGK AIRSSPELFS STVLPLPADS
1300
1301
PTHQPLLLPP LQTPKLYGSP TQIGPSYRGM INVSTSSDMD HNSAVPGSQV
1350
1351
SSNVGDVMSF SVTVTTIPAS QAMNPSSHGQ TIPVQAFSEE NSIEGTPSKC
1400
1401
YCRLKAMIMC KGCGAFCHDD CIGPSKLCVS CLVVR                
1435
 

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Checksums:
CRC64:A01026E3C2D1035D
MD5:b25d1db2f9d1ad5436b6acfa7e806f9f

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.