Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: Q7K4Q9_DROME (Q7K4Q9)

Summary

This is the summary of UniProt entry Q7K4Q9_DROME (Q7K4Q9).

Description: 3-hydroxy-3-methylglutaryl coenzyme A synthase {ECO:0000256|RuleBase:RU364071}
Source organism: Drosophila melanogaster (Fruit fly) (NCBI taxonomy ID 7227)
Length: 465 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
Pfam HMG_CoA_synt_N 5 178
Pfam HMG_CoA_synt_C 179 457
disorder n/a 459 465

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q7K4Q9. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MASHWPENVG IRAIEILFPS QYVDQTELET FDGASAGKYT IGLGQAKMGF
50
51
CSDREDVNSL CLTVVSRLLE RQHVKHSEIG RLEVGTETIV DKSKSVKSVL
100
101
MQLFAESGNT DIEGIDTTNA CYGGTAALFN AVNWVESSSW DGRLALAVCA
150
151
DIAVYAKGAA RPTGGAGAVA MLVGPNAPLI LDRGLRATHM EHAYDFYKPD
200
201
LSSEYPTVDG KLSIQCYLSA LDTCYRLYRK KFDQQQKDTS KQPASLSTFD
250
251
AILFHTPFCK LVQKSVGRLS FNDFLLSSEE ERTKQFPDLE RFNTATLEST
300
301
YFDRDVEKAF MTQSANIFAS KTKKSLLLAN QVGNMYTPSV YSGLVSLLIS
350
351
GPAQELVGKR IGLFSYGSGL AASMYSISVT QDAAAFEKFV SQLDYVQPLL
400
401
NSREKVAPEQ FSALMEVREK NNHAAPYTPT GSISALFPGT YYLKDVDALH
450
451
RRTYERTPTI SNGVH                                      
465
 

Show the unformatted sequence.

Checksums:
CRC64:57AA3A9FA4D424C8
MD5:52b78f142182a133def767eed988ccb5

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;