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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: SV2A_HUMAN (Q7L0J3)

Summary

This is the summary of UniProt entry SV2A_HUMAN (Q7L0J3).

Description: Synaptic vesicle glycoprotein 2A
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 742 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
low_complexity n/a 19 32
disorder n/a 33 34
low_complexity n/a 39 58
disorder n/a 40 144
low_complexity n/a 123 138
Pfam Sugar_tr 148 484
transmembrane n/a 166 193
transmembrane n/a 205 222
transmembrane n/a 234 251
low_complexity n/a 240 252
transmembrane n/a 257 281
low_complexity n/a 265 276
transmembrane n/a 293 315
transmembrane n/a 335 353
transmembrane n/a 446 464
Pfam MFS_1 555 739
transmembrane n/a 595 618
transmembrane n/a 625 644
transmembrane n/a 650 672
transmembrane n/a 684 707
transmembrane n/a 713 731
low_complexity n/a 713 725
low_complexity n/a 717 731

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q7L0J3. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEEGFRDRAA FIRGAKDIAK EVKKHAAKKV VKGLDRVQDE YSRRSYSRFE
50
51
EEDDDDDFPA PSDGYYRGEG TQDEEEGGAS SDATEGHDED DEIYEGEYQG
100
101
IPRAESGGKG ERMADGAPLA GVRGGLSDGE GPPGGRGEAQ RRKEREELAQ
150
151
QYEAILRECG HGRFQWTLYF VLGLALMADG VEVFVVGFVL PSAEKDMCLS
200
201
DSNKGMLGLI VYLGMMVGAF LWGGLADRLG RRQCLLISLS VNSVFAFFSS
250
251
FVQGYGTFLF CRLLSGVGIG GSIPIVFSYF SEFLAQEKRG EHLSWLCMFW
300
301
MIGGVYAAAM AWAIIPHYGW SFQMGSAYQF HSWRVFVLVC AFPSVFAIGA
350
351
LTTQPESPRF FLENGKHDEA WMVLKQVHDT NMRAKGHPER VFSVTHIKTI
400
401
HQEDELIEIQ SDTGTWYQRW GVRALSLGGQ VWGNFLSCFG PEYRRITLMM
450
451
MGVWFTMSFS YYGLTVWFPD MIRHLQAVDY ASRTKVFPGE RVEHVTFNFT
500
501
LENQIHRGGQ YFNDKFIGLR LKSVSFEDSL FEECYFEDVT SSNTFFRNCT
550
551
FINTVFYNTD LFEYKFVNSR LINSTFLHNK EGCPLDVTGT GEGAYMVYFV
600
601
SFLGTLAVLP GNIVSALLMD KIGRLRMLAG SSVMSCVSCF FLSFGNSESA
650
651
MIALLCLFGG VSIASWNALD VLTVELYPSD KRTTAFGFLN ALCKLAAVLG
700
701
ISIFTSFVGI TKAAPILFAS AALALGSSLA LKLPETRGQV LQ        
742
 

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Checksums:
CRC64:913E216D5CFC2FB2
MD5:76a8037c47360bd88e8524de2c1a0a25

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.