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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: Q7PLB8_DROME (Q7PLB8)

Summary

This is the summary of UniProt entry Q7PLB8_DROME (Q7PLB8).

Description: 3-oxoacyl-[acyl-carrier-protein] reductase {ECO:0000256|ARBA:ARBA00018576}
Source organism: Drosophila melanogaster (Fruit fly) (NCBI taxonomy ID 7227)
Length: 2394 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 5 10
Pfam ketoacyl-synt 18 256
disorder n/a 58 59
Pfam Ketoacyl-synt_C 260 377
Pfam KAsynt_C_assoc 380 490
Pfam Acyl_transf_1 517 832
disorder n/a 805 806
Pfam PS-DH 871 1112
low_complexity n/a 1135 1146
low_complexity n/a 1295 1306
transmembrane n/a 1520 1539
transmembrane n/a 1551 1571
Pfam ADH_zinc_N 1559 1685
Pfam KR 1760 1940
Pfam PP-binding 2000 2066
Pfam Thioesterase 2121 2374
transmembrane n/a 2182 2201

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q7PLB8. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MESTKNKKYS RSFPDTDGDD IVISGMAGKF PNCRNITEYQ YKLYNKIDMV
50
51
DDDERRWRHF NPEIPKRSGK ICDLEKFDAT FFGVHFKQAH TMDPQTRILI
100
101
ETAYEAVIDS GVNPKSLRGS KTGVYIGSCI SESEKTWFYE KVSSGGFGIT
150
151
GCSRAMMANR ISYCLGLEGP SFLLDTACSS SMYALDNAFS AIRNGEIDAA
200
201
IIGGSNLLLH PFVTLQFARL GVLAPDGFCR PFDKNASGYT RSETINCLFL
250
251
QKKKHAKRVY ASIVYSKTNC DGYKPEGITY PSGIVQEKLL DQFYKDIDHK
300
301
PSDLGYLEAH STGTVVGDPE ECKAIDNVLC SQREEPLLVG SVKSNVGHSE
350
351
AASGICSLVK ACFAFETGLI APNINFTEVK QIIAPLAEGR LIVVKDVVPL
400
401
PKPYIGINSF GFGGANAHAL LKGYPKSKNN FGIPADDVPR LLTWAGRTEE
450
451
AVEEIFNAVE KNPLDAEFIG LLQNIQEEDV SGMVFRGYAI FAKQGTGPCK
500
501
LLAKDVQHYT GLQRPIVWVY SGMGSQWNQM GNSLMIIPRF RESVEICHQI
550
551
LLAKGLNLIH ILTSNDPEVY QNILNSFVGI AAVQIGLTDV LRSLNIQPDY
600
601
IIGHSVGELG CAYADGGLTA QQMILAAYYR GRVSVDLEKI RGSMAAVGLG
650
651
YKTVLHMLPK SIETACHNGP DSCTISGPVD DVAQFVADLK TKGIFAKEVP
700
701
CSNIAYHSKY ISHMGPPLLN YMNEIIPHPK PRTKKWLSTS VPKIDWNKDK
750
751
AKFCSAEYHT NNLLNSVLFD ETFSLIPKNS LTIEVAPHGL LGAILKRSMP
800
801
SGVHIPLTNR GNQNNASFFL SALGKIYLNG VLLPAANLYE RIQFPVSRTT
850
851
PSVSSLIRWD HSEDWFVTKY ENMKTKSSGE RVFSVNLASD NEEFLSGHII
900
901
DGKILVPATC YLQYVWETFS LMYHGPSYMD VPVEFEDIRF IRATSMPVDG
950
951
KVDLTVMIHY GTGHFEITEM GSLVVTGIIR ETENPSIPEV YNFQSKSKFP
1000
1001
MIAKKDFYKE LKLRGYHYNG AFQAVNLARS DGLFGRVQWN YNWVTFMDAM
1050
1051
LQIQILGTDS RNLLLPTKIR KLKINGVHHF DLMTKMDPEN RVFDVYVDPM
1100
1101
YDRIIAGGIE IFGLHASLVQ RRRPPGIPVL EEYVFLPFFS SSILSLKNAA
1150
1151
RVCVQIAIEN NPTLKLKLVE VGADGKNHML TEFIEAIQDL PVITGDYILL
1200
1201
TSQNLEDLPG VHIENGSLST QTNCHIIIIG GYEEDEVHEK ITSAYNVLVD
1250
1251
NGYIVFRQKC AKNVSCKIAE KFRTISKIPI NNTEENLVLL QKISKKLTVP
1300
1301
PVLVKVSQHD KTFEWILELQ SAIITKAPVV VYSFNEKLNG QIGLVNCLRK
1350
1351
EPDGNLIRCF FIDDDSAPDF DLSHPFYSTQ YSLGLAFNIY RNGSWGSYRH
1400
1401
LQLLKNDQPS KRLDHIYGNV IQRGDLSSLQ WLKGPFNSQN CHIKIAFSSL
1450
1451
NFRDVMLATG RLAVELYGSS RIDQNCVLGF EYSGINMLTG RRIMSMVVKG
1500
1501
GVASYVEKPS KLIWDIPDDW SLEEAATVPV VYITVYYAFF MATDIRKGKS
1550
1551
ILIHAGTGGI GLAAIRVALA YNLEVFTTCS TANKKEFLLK TFPKLKESHI
1600
1601
GNSRNTSFEL MVHRETNGKG VDFVLNSLSE EKLLASLRCL GKSGHFLEIG
1650
1651
KYDMANDNKI GLGCFLKEIT FHAVLADSLL VAPDEDIWHL KSLIDMDISN
1700
1701
GIIQPLPVKV FLAHEIEQAF RHLIGGKHIG KVVIQVREQP HDPSTLPVRV
1750
1751
LNQVYFKHNH TYVIPGGLGG FGMELADWMA IRGARKLLLS SSRGITKDYQ
1800
1801
LYRIALWKTY GCEVAISTAD ITSKKGCAQL LSEANGMGPV GGIFNLAVVL
1850
1851
KDCIFSNQNV NQFLECFAPK AIATTYLDDL SRIYCPELEH FVVFSSVSCG
1900
1901
RGNAGQSNYG MANSVMERII EHRNREGFPG KAIQWGAIGE VGLVADMAED
1950
1951
KIDMEIGGTL QQRISSCIQE LDHLLCADAS IVSSMVVAEK RTMRSGQGNV
2000
2001
IDAVMNIMGI RDLKSVSLST TLSEMGMDSL MAVEIKQTLE RDFELILTPQ
2050
2051
DLRHLTFQKL QEFIDAKEKE NTDGIQIIFA SDNKLLGMEL LIRNLGDEAN
2100
2101
CDQIIIPLQT SAAPSKQNLQ PNIIIPGLEG TAGRAWYQLG SKLQSPAIVL
2150
2151
QLHQFAHLEN LKDVAQQSFD QIKLILKQTE PFYIIAYSYG TFVALLLAEM
2200
2201
LENSGFRGHL MLLDGAPHFL KRLTNLHLGE QFSDNDLYDL LFSSIVNHIF
2250
2251
PEASKESMST VFHQVDCLSD KMSLFMNYVE KQNMYSKKYS STMVKAMFNR
2300
2301
VKMAASFDLD GIIKIKSPIT LVRPAEASLQ DIDEDYCISL LTSGVVTLKV
2350
2351
IEGNHTTMLD NPSLSQIIDD FDPVLLEDKH FEEYIRNDKP VSVV      
2394
 

Show the unformatted sequence.

Checksums:
CRC64:42F6C47146DA9325
MD5:fab1022462e6db2c095fe6c279306c33

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;