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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: CTIP_MOUSE (Q80YR6)

Summary

This is the summary of UniProt entry CTIP_MOUSE (Q80YR6).

Description: DNA endonuclease RBBP8 EC=3.1.-.-
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
Length: 893 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 12
Pfam CtIP_N 20 139
coiled_coil n/a 56 83
disorder n/a 100 105
coiled_coil n/a 110 144
disorder n/a 120 122
disorder n/a 125 143
disorder n/a 145 147
disorder n/a 150 156
disorder n/a 181 182
disorder n/a 184 187
disorder n/a 198 203
disorder n/a 205 227
disorder n/a 235 241
disorder n/a 255 283
disorder n/a 293 327
disorder n/a 369 372
disorder n/a 377 383
disorder n/a 411 420
disorder n/a 440 452
disorder n/a 454 458
disorder n/a 474 527
disorder n/a 529 530
disorder n/a 532 540
disorder n/a 560 561
disorder n/a 563 589
disorder n/a 593 595
disorder n/a 598 600
disorder n/a 638 641
disorder n/a 646 652
disorder n/a 664 669
disorder n/a 672 685
disorder n/a 701 724
disorder n/a 736 738
disorder n/a 740 765
disorder n/a 788 792
Pfam SAE2 816 854
disorder n/a 870 871
disorder n/a 875 893

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q80YR6. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSISGSGCGS PNSADASNDF KELWTKLKEY HDKEVQGLQV KVTKLKKERI
50
51
LDAQRLEEFF TKNQQLRDQQ KVLQETIKIL EDRLRAGLCD RCAVTEEHMH
100
101
KKQQEFENIR QQNLKLITEL MNEKNTLQEE NKKLSEQLQQ KMENGQQDQV
150
151
AELACEENII PDSPVTSFSF SGINRLRKKE NLHVRYVEQT HTKLERSLCT
200
201
NELRKISKDS APAPVNSEEH EILVADTCDQ NHSPLSKICE TSSYPTDKTS
250
251
FNLDTVVAET LGLNGQEESE PQGPMSPLGS ELYHCLKEDH KKHPFMESAR
300
301
SKEDSLRFSD SASKTPPQEF TTRASSPVFG ATSTVKAHLG LNTSFSPSLL
350
351
DIGKKNLLKT APFSNIAVSR SEKVRSKSED NALFTQHSLG SEVKVISQSF
400
401
SSKQILTNKT VSDSVDEQCS ADHMNTTVAD KYLVPLKSLG GKASKRKRTE
450
451
EESEHAVKCP QACFDKENAL PFPMENQFSM NGDHVMDKPL DLSDRFAATQ
500
501
RQEKNHGNET SKNKLKQATI YEALKPIPKG SSSGRKALSG DCMPAKDSWE
550
551
TYCLQPRSLQ SSSKFSPDQK TPLQIKEENP VFKTPPCSQE SLETENLFGD
600
601
VKGTGSLVPT KVKSRAVHGG CELASVLQLN PCRVAKTKAL PSNQDTSFEN
650
651
IQWSVDPGAD LSQYKMDVTV IDTKDSSHSR LGGETVDMDC TLVSETVLLK
700
701
MKKQEQKERS PNGDIKMNDS LEDMFDRTTH EEYESCLADS FSQVPDEEEL
750
751
PDTTKKTNIP ADKQDGVKQK AFVGPYFKDK ERETSIQNFP HIEVVRKKEE
800
801
RRKLLGHTCK ECEIYYADLP AEEREKKLAS CSRHRFRYIP PNTPENFWEV
850
851
GFPSTQTCLE RGYIKEDLDL SPRPKRRQPY NAVFSPKGKE QRT       
893
 

Show the unformatted sequence.

Checksums:
CRC64:2F363F88D2190F13
MD5:0523f8a5f6bcf0f2a9d3d0bf8a447587

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;