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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: HMCSB_DICDI (Q86HL5)

Summary

This is the summary of UniProt entry HMCSB_DICDI (Q86HL5).

Description: Hydroxymethylglutaryl-CoA synthase B EC=2.3.3.10
Source organism: Dictyostelium discoideum (Slime mold) (NCBI taxonomy ID 44689)
Length: 468 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam HMG_CoA_synt_N 3 176
low_complexity n/a 87 100
Pfam HMG_CoA_synt_C 177 461
low_complexity n/a 338 354
low_complexity n/a 371 384
disorder n/a 379 384

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q86HL5. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MKKTKDIGIC AIDIYFPQTY VNQSELKKYD KVSNGKYTIG LGQTNMSFVG
50
51
DREDIVSMAM TSVKMMMSKY SIDYQSIGRL EVGTETIIDK SKSVKSSIMS
100
101
LFQEYGNTSL EGVDTLNACY GGTNALFNSL QWIESSYWDG RYALVVTGDI
150
151
AVYSKGAARP TGGAGVVTML IGPNATLIFD QSLRGTHMEN VNDFYKPDLS
200
201
SEYPYVDGKL SIECYLRALD KCYLEYKKKF ESINDDNKFS MDSFDYVCFH
250
251
SPYNRLVQKS YARLIYNDFL QNPNNPKYQD LLPFKDLSTG KDSYINSKLD
300
301
QITLKLSLDD FKTKVNPSTL LSKECGNSYC GSVYSGILSL LSNVNDLNNK
350
351
KVLVFSYGSG LAASLFSFRI NNNKNRNNNN NNNNCFFKTT NDIGKISNIK
400
401
ERLSNRVKVS PEEFTRILDI REKSHQMVGA RTPIDTLDYI SAGTFYLEKI
450
451
DEKLIRHYKS KPIISSKL                                   
468
 

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Checksums:
CRC64:D44CCE967EF23BC6
MD5:ae123afe03af2f13b3fb0e411c196ff9

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;