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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: Q8IE49_PLAF7 (Q8IE49)

Summary

This is the summary of UniProt entry Q8IE49_PLAF7 (Q8IE49).

Description: DNA-directed RNA polymerase subunit {ECO:0000256|RuleBase:RU004279}
Source organism: Plasmodium falciparum (isolate 3D7) (NCBI taxonomy ID 36329)
Length: 2356 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
coiled_coil n/a 2 22
Pfam RNA_pol_Rpb1_1 32 354
Pfam RNA_pol_Rpb1_2 356 462
disorder n/a 431 432
low_complexity n/a 431 454
low_complexity n/a 451 471
low_complexity n/a 485 500
Pfam RNA_pol_Rpb1_2 490 637
low_complexity n/a 508 525
disorder n/a 521 530
disorder n/a 532 540
Pfam RNA_pol_Rpb1_3 640 814
low_complexity n/a 819 830
Pfam RNA_pol_Rpb1_4 839 945
Pfam RNA_pol_Rpb1_5 952 1046
low_complexity n/a 1039 1051
Pfam RNA_pol_Rpb1_5 1059 2283
disorder n/a 1059 1080
low_complexity n/a 1069 1097
disorder n/a 1082 1200
low_complexity n/a 1089 1147
low_complexity n/a 1139 1187
low_complexity n/a 1179 1201
disorder n/a 1202 1204
low_complexity n/a 1294 1304
disorder n/a 1300 1302
disorder n/a 1305 1313
disorder n/a 1316 1317
disorder n/a 1320 1332
disorder n/a 1336 1338
low_complexity n/a 1342 1358
disorder n/a 1363 1364
disorder n/a 1397 1398
disorder n/a 1453 1456
coiled_coil n/a 1459 1479
low_complexity n/a 1460 1479
disorder n/a 1479 1482
disorder n/a 1484 1489
low_complexity n/a 1488 1500
low_complexity n/a 1501 1516
disorder n/a 1512 1571
low_complexity n/a 1529 1577
disorder n/a 1591 1600
low_complexity n/a 1597 1610
disorder n/a 1603 1611
low_complexity n/a 1772 1787
low_complexity n/a 1919 1935
disorder n/a 2007 2008
disorder n/a 2017 2019
coiled_coil n/a 2017 2037
disorder n/a 2021 2026
disorder n/a 2049 2107
low_complexity n/a 2053 2093
coiled_coil n/a 2114 2134
low_complexity n/a 2120 2134
disorder n/a 2124 2126
disorder n/a 2130 2131
low_complexity n/a 2177 2187

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q8IE49. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MMKKKNIDIE ELKRLIEESS MKKRFVKDIK RNCEIKSIRF GIMSKEDIIK
50
51
YSEVKIMNRE MYKNNSGIPY PYGVLDLKLG AHKSNSVCET CNKKLINCSG
100
101
HFGYIELNYP VFHIGYYKYI IHILYCICKY CSSLLLSKEK IDFYCNLKKK
150
151
STDDSFYKKH LFKRILNNCK KVNKCYICGN PQGVIKKIIK PSLDQFMKLK
200
201
HILKVKENGK MIIKEEDLNS LYVLKLFKNI NPYHVKLLNI ENPEKLIITA
250
251
LLVPPNTIRP SVIIDEHGTA EDDLTCILSE ITQLNNTIYN QCTNGYQTNQ
300
301
FLGNVEFLQL QITRFINSDS PAVSQLLATQ NISKPGRGIC QRLKGKEGRF
350
351
RCNLSGKRVD FSSRTVISPD PNISIDEVVI PKIIAMRLTY PETVNKYNID
400
401
KLKMLIKNGC NKWPGANYII KKSKKGIDPY SDISTSYNNN SNNISSIGCS
450
451
NIFNVVNNYI NNNCKNVRYN IKDVNNNVLL KDMCDINNMN NDINNNINNI
500
501
YKNTSETNLC NVNNHNNNNN IYCNNQTQDN EEERKNSQFN KISLKYANKN
550
551
HVIQNLNIGD VVERHICDGD IVLFNRQPSL HRMSIMCHKA KIMDFKTFRF
600
601
NECVCSPYNA DFDGDEMNLH VPQTEEARAE ALYLMNVKHN LITPKNGEVI
650
651
IALTQDFLSA SYIITNKDTF LDRDTFCLLC SYFSDASLYI ELPIPAILKP
700
701
KELWTGKQLI SVLIKPNKKE NTIINFEIQE REYSNKFGDL KHLCLNDSYV
750
751
CFYKSELICG SLGKKVLGSS KYGLFYYLIH HNSSHIALKI MNRLSKLTSR
800
801
YFSNKGMTIG IDDVRPSQTL TEKKKDLLLK GYEKVNNEII LYNEKKMQIQ
850
851
PGCTLEETLE IKVKSILDDL RNDAGKTCNQ YLHYLNKPLI MFNSGAKGAL
900
901
INIAQMIACV GQQNVAGQRI QNGFINRTLP HFHFHCKDSE SRGFVQNSFY
950
951
TGLSPTEFFF HTMSGREGLV DTAVKTAETG YMQRRLMKAL EDLSIHYDYS
1000
1001
VRSCDKQIVQ FIYGDDALNP SYIDNNNTYL DQFDKVFDHI VSISSSHLLL
1050
1051
SYKNKIPYLP HVQHQNKTSN MNNIYNNMNN INNNDSNRSI IYNNDSNMNN
1100
1101
INNNDSNMNN INNNDSNMNS IHNNNSNMNN IHNNDSNRSI IHNNDSNMNS
1150
1151
IHNNDSNMNS IHNNNSNMNN IHNNDSNRSI IHNNDSNMNS IHNNDSNNNN
1200
1201
NYKDCTHNPY ICNESLIIRN IMNRLIYQNI AQEDLFIPLE HDEFLVNKIM
1250
1251
ESYTDQECNY EDIIRSLDLN KNVSYIHNDQ GKHLSLQMCA EEHITINNTN
1300
1301
NDNTYVEQIE MKELSKNKTK EKQSFKGTIR DMHEDSEEQM NKFITKKAKF
1350
1351
FIEKKKGKMH ECNDDIEYNN TQYDNIQYNN ISCNYIKSQN LENTHHQVNN
1400
1401
DLSFIKNNVI LPPKEYHSIF HFVNDYRNVV EIKNLMDKKK IFLNNSEKNV
1450
1451
VQSKYNRMSK NLKKKIEIIN NIYRNEKKKL NRWKTKMDND DNYWSSDDDS
1500
1501
IIAKKIIKIK NKEKRKYHPK EEKENFDRNN YKMITDNNNN DNNNNNNDNN
1550
1551
NNDNNNNNNN NSNNNNYYYN LHDDVNNLGV TNYNTNIYPN DCNGIYEKET
1600
1601
NNNELTTNSN MCDKNNDFSD EFFNNINEND LLYDNKYYRQ IFKNVIGFVS
1650
1651
VFEYVESYKQ HYILFPYEII KWTSFLLEYL TEIIPTNIFL HTKLSKKEKP
1700
1701
THQKNTGKMK IYIEEIKKWL FIKAINIYKY FSFKKSIELI KKKDYFNYII
1750
1751
KNYDISHRYI IHDYSFINLK QLYLFIFFNI YKYFKYISTP GDAVGSISAQ
1800
1801
SIGEPGTQMT LKTFHFAGVA SMNVTLGVPR IKEIINASNS IQTPILNIPL
1850
1851
EVNDNYNFAL MMKSKLEKTT IRDICMYIKE DYTSRGVFLS VKFNEELIQK
1900
1901
LFLNINAYNI KDIILKQSHI NKIKINKIHI NVINKYKLHI SLKNDEFIFF
1950
1951
QMESLKKGLL DLLIYGDKDI KRCIIKKEDI EVTDNEDEIC DDMDEYYNVS
2000
2001
QGTELYERKC NSKEENKNAI RVKKEEIDDN LEKEENIIYV SEKDSVNQLK
2050
2051
SEKKKDINDD NNNNDDNNNN DDNNNNNDDD NKINDTIFND DINSDRNNLK
2100
2101
ENGSKLENVG EHIIERLSYK MKEKNVKKEH IKKEPNLINL DTINLDTLNF
2150
2151
DEINVHNINN EKIEFYDEHL NICQGNKKHI QKKKKKKTVY SILVEGNSLN
2200
2201
YVLGLEGVDF KHIISNHVIN VFQVLGIEAA RITIINEIKK CVEAYSIDID
2250
2251
IRHIMLLADI MAFTGDILGI NRFGIQKARQ STLMLASFEE TNEHLFVSSF
2300
2301
FKNVDEINNI SESIIVGKNI PIGTGAFQLL YDYKFEKETK NLTLLEKAER
2350
2351
ETAMNY                                                
2356
 

Show the unformatted sequence.

Checksums:
CRC64:09E365F70EE1ECBF
MD5:3f8e227f41467e529b48e287332212ed

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;