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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: DCL1_ORYSJ (Q8LMR2)

Summary

This is the summary of UniProt entry DCL1_ORYSJ (Q8LMR2).

Description: Endoribonuclease Dicer homolog 1 EC=3.1.26.-
Source organism: Oryza sativa subsp. japonica (Rice) (NCBI taxonomy ID 39947)
Length: 1883 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
disorder n/a 1 7
low_complexity n/a 2 18
disorder n/a 45 50
disorder n/a 66 109
low_complexity n/a 75 97
low_complexity n/a 104 129
disorder n/a 122 123
disorder n/a 125 213
low_complexity n/a 144 148
low_complexity n/a 171 182
low_complexity n/a 177 197
disorder n/a 220 262
transmembrane n/a 284 304
transmembrane n/a 316 339
disorder n/a 465 466
disorder n/a 577 604
Pfam Helicase_C 624 745
disorder n/a 687 689
disorder n/a 768 771
disorder n/a 773 780
disorder n/a 789 790
Pfam Dicer_dimer 817 908
disorder n/a 903 928
Pfam PAZ 1163 1318
Pfam Ribonuclease_3 1353 1498
disorder n/a 1439 1441
disorder n/a 1451 1455
disorder n/a 1458 1462
disorder n/a 1519 1524
Pfam Ribonuclease_3 1573 1686
disorder n/a 1707 1718
low_complexity n/a 1774 1785
disorder n/a 1776 1795
Pfam DND1_DSRM 1796 1871
disorder n/a 1817 1818
disorder n/a 1830 1831
disorder n/a 1843 1852
disorder n/a 1875 1883

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q8LMR2. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAGGGGVGGG AGEHAAAAYW YDACEDGASL LCGIDFAASA DFDPGLIPAM
50
51
DTGADDGFVA EIDRILESIN AESSPAPPPP PPPPLPEPVP VAPPELPIQE
100
101
KQLQVASAPV ANNAVAVVGV VQRSKGVVAR KEPRRESHGC AANGGGGGEW
150
151
RDGKRPRLAS GGVGGPRQEW RRRPMLPPPP SRGWDDRRGR RDFDRVRKHE
200
201
HHRREARGFW ERDRGGKMVF RSGTWEQESD REAKRARTQD GGSMEKKAEA
250
251
DRMGAAQREK PVAEERARQY QLEVLEQAKS RNTIAFLETG AGKTLIAVLL
300
301
IKSVCDKMLK ENKKMLAVFL VPKVPLVYQV LVMTAQILLN ILRHSIIKMD
350
351
AIHLLILDEC HHAVKKHPYS LVMSEFYHTT PKEKRPAVFG MTASPVNLKG
400
401
VTSQEDCAIK IRNLESKLDS VVCTIKDRKE LEKHVPMPLE VVVQYDKAAT
450
451
LWSLHEQIKQ MESTVEEAAL SSSKRTKWQF MGARDAGSRD ELRLVYGVSE
500
501
RTESDGAANL IQKLRAINYA LGELGQWCAY KVAQSFLTAL QNDERANYQV
550
551
DVKFQESYLK KVVDLLHCQL TEGAAMKSET SDVEMQNTEK HNTNDLEEGE
600
601
LPDSHGEHVD EVIGAAVADG KVTPRVQALI KILLKYQHTE DFRAIIFVER
650
651
VVTALVLPKV LAELPSLSFI RCASLIGHNN NQEMRACQMQ DTISKFRDGR
700
701
VTLLVATSVA EEGLDIRQCN VVIRFDLAKT VLAYIQSRGR ARKPGSDYIL
750
751
MLERGNISHE TFLRNARNSE ETLRKEAMER TDLSHLDGTS VLSPVDTSPG
800
801
SMYQVESTGA VVSLNSAVGL IHFYCSQLPS DRYSILHPEF IMQKYEKPGG
850
851
SVEYSCKLQL PCNAPFEKLE GPICSSIRLA QQAVCLAACK KLHEMGAFTD
900
901
TLLPDRGSGE GEKTEQNDEG EPLPGTARHR EFYPEGVADI LRGEWILSGR
950
951
DGYQNSQFIK LYMYSVNCVN VGTSKDPFVT QLSNFAIIFG NELDAEVLST
1000
1001
TMDLFVARTM ITKASLVFRG RIEITESQLV LLKSFHVRLM SIVLDVDVDP
1050
1051
STTPWDPAKA YLFVPVGAEK CTDPLREIDW TLVNNIVNTD AWNNPLQRAR
1100
1101
PDVYLGTNER TLGGDRREYG FGKLRHGTAF GQKAHPTYGI RGAIAEFDIV
1150
1151
KASGLVPARD RGHFSDYQNQ GKLFMADSCW NAKDLAGMVV TAAHSGKRFY
1200
1201
VDCICYNMNA ENSFPRKEGY LGPLEYSSYA DYYKQKYGVE LIYRKQPLIR
1250
1251
ARGVSYCKNL LSPRFEHSDA REGDFSENLD KTYYVYLPPE LCLVHPLPGS
1300
1301
LVRGAQRLPS IMRRVESMLL AVQLKDIIDY PVPATKILEA LTAASCQETL
1350
1351
CYERAELLGD AYLKWVVSRF LFLKYPQKHE GQLTRMRQQM VSNMVLYQYA
1400
1401
LNKTLQSYIQ ADRFAPSRWA APGVLPVFDE ESREYEPSIF DEESTGCELQ
1450
1451
KESYDDYADN MQEDGEIEGD SSCYRVLSSK TLADVVEALI GVYYVAGGKI
1500
1501
AANHLMKWIG IHAELDPEEI PPPKPYDIPE SIMRSINFDT LKGVLGIEFQ
1550
1551
NKGLLVEAIT HASRPSSGVS CYQRLEFVGD AVLDHLITRH LFFTYTDLPP
1600
1601
GRLTDLRAAA VNNENFARVA VKHKLHVHLR HGSSALETQI REFVKDVQEE
1650
1651
LLKPGFNSFG LGDCKAPKVL GDIVESIAGA IFLDSGYDTS VVWKVFQPLL
1700
1701
HPMVTPETLP MHPVRELQER CQQQAEGLEY KASRAGNIAT VEVFVDGVQI
1750
1751
GVAQNPQKKM AQKLAARNAL VVLKEKETAT KKEDERDGEK KNGAQMFTRQ
1800
1801
TLNDICLRRQ WPMPQYRCVN EGGPAHAKRF VYSVRVNTSD RGWTDECIGE
1850
1851
PMPSVKKAKD SAAVLLLELL NRDFPDKPDG KQP                  
1883
 

Show the unformatted sequence.

Checksums:
CRC64:0566ADA02CA424CF
MD5:7b2dc04f119aec6b617e27feb83db263

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;