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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: SC5A8_HUMAN (Q8N695)

Summary

This is the summary of UniProt entry SC5A8_HUMAN (Q8N695).

Description: Sodium-coupled monocarboxylate transporter 1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 610 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
transmembrane n/a 12 34
low_complexity n/a 26 38
Pfam SSF 45 449
transmembrane n/a 54 72
transmembrane n/a 84 108
transmembrane n/a 129 150
transmembrane n/a 162 182
transmembrane n/a 194 218
transmembrane n/a 240 259
low_complexity n/a 241 254
transmembrane n/a 280 302
transmembrane n/a 340 369
transmembrane n/a 390 410
low_complexity n/a 398 415
transmembrane n/a 416 436
transmembrane n/a 443 463
transmembrane n/a 521 541
low_complexity n/a 525 545
disorder n/a 579 580
disorder n/a 588 598
disorder n/a 603 604
disorder n/a 606 610

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q8N695. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDTPRGIGTF VVWDYVVFAG MLVISAAIGI YYAFAGGGQQ TSKDFLMGGR
50
51
RMTAVPVALS LTASFMSAVT VLGTPSEVYR FGAIFSIFAF TYFFVVVISA
100
101
EVFLPVFYKL GITSTYEYLE LRFNKCVRLC GTVLFIVQTI LYTGIVIYAP
150
151
ALALNQVTGF DLWGAVVATG VVCTFYCTLG GLKAVIWTDV FQVGIMVAGF
200
201
ASVIIQAVVM QGGISTILND AYDGGRLNFW NFNPNPLQRH TFWTIIIGGT
250
251
FTWTSIYGVN QSQVQRYISC KSRFQAKLSL YINLVGLWAI LTCSVFCGLA
300
301
LYSRYHDCDP WTAKKVSAPD QLMPYLVLDI LQDYPGLPGL FVACAYSGTL
350
351
STVSSSINAL AAVTVEDLIK PYFRSLSERS LSWISQGMSV VYGALCIGMA
400
401
ALASLMGALL QAALSVFGMV GGPLMGLFAL GILVPFANSI GALVGLMAGF
450
451
AISLWVGIGA QIYPPLPERT LPLHLDIQGC NSTYNETNLM TTTEMPFTTS
500
501
VFQIYNVQRT PLMDNWYSLS YLYFSTVGTL VTLLVGILVS LSTGGRKQNL
550
551
DPRYILTKED FLSNFDIFKK KKHVLSYKSH PVEDGGTDNP AFNHIELNSD
600
601
QSGKSNGTRL                                            
610
 

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Checksums:
CRC64:47FF410B895DB692
MD5:209e8f11489dbd9577825bbc3a6cd021

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.