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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ZN420_HUMAN (Q8TAQ5)

Summary

This is the summary of UniProt entry ZN420_HUMAN (Q8TAQ5).

Description: Zinc finger protein 420
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 688 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam KRAB 5 46
disorder n/a 63 64
disorder n/a 90 95
disorder n/a 100 101
Pfam zf-C2H2 139 161
disorder n/a 155 157
Pfam zf-C2H2 167 189
Pfam zf-C2H2 195 217
Pfam zf-C2H2 223 245
Pfam zf-C2H2 251 273
Pfam zf-C2H2 279 301
Pfam zf-C2H2 335 357
Pfam zf-C2H2 363 385
Pfam zf-C2H2 391 413
disorder n/a 407 409
Pfam zf-C2H2 419 441
disorder n/a 435 437
Pfam zf-C2H2 447 469
disorder n/a 463 465
disorder n/a 467 468
Pfam zf-C2H2 475 497
disorder n/a 491 493
Pfam zf-C2H2 503 525
disorder n/a 519 521
Pfam zf-C2H2 531 553
Pfam zf-C2H2 559 581
disorder n/a 575 577
Pfam zf-C2H2 587 609
Pfam zf-H2C2_2 629 654
disorder n/a 631 633

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q8TAQ5. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MARKLVMFRD VAIDFSQEEW ECLDSAQRDL YRDVMLENYS NLVSLDLPSR
50
51
CASKDLSPEK NTYETELSQW EMSDRLENCD LEESNSRDYL EAKGKMEKQQ
100
101
ENQKEYFRQG MIIYDKMSIF NQHTYLSQHS RCHSTEKPYK CKECGKAFRR
150
151
ASHLTQHQSI HTGEKPYECK QCGKAFSRDS QLSLHQRLHT GEKPYACKEC
200
201
GKAFTQSSQL ILHHRIHTGE KPYKCEECGK AFIRSSQLTR HQKVHTGEKP
250
251
YECKECGKAF TQNSQLTLHQ RLHTGEKLYE CKECRKVFTQ LSQLILHKRI
300
301
HTGEKPYECK ECGKAFICGS QLSQHQKIHN GEKPYECKEC GRAFIRGSLL
350
351
MQHQRIHTGE KPYKCEECGK AFIRGSQLTQ HQRIHTNEKP YECKECGKMF
400
401
SHGSQLTQHQ RIHTGEKPYQ CKECGKAFNR GSLLTRHQRI HTGEKPYECK
450
451
ECGKTFSRGS ELTQHERIHT GEKPYECKEC GKSFIRGSQL TQHQRIHTGE
500
501
KPYECKECRM AFTQSSHLSQ HQRLHTGEKP YVCNECGKAF ARGLLLIQHQ
550
551
RIHTGEKPYQ CKECGKAFIR GSQLTQHQRI HTGEKPYECK ECGKAFSHGS
600
601
QLTLHQRIHT GEKPYECREC RKAFTQSSHL SRHQRIHTGE KPYQCKECGK
650
651
AFTRGSQLTQ HQRIHISEKS FEYKECGIDF SHGSQVYM             
688
 

Show the unformatted sequence.

Checksums:
CRC64:70E984F166F8A975
MD5:da53ee56c048354c0ee5496df004ec38

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;