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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ZIC5_HUMAN (Q96T25)

Summary

This is the summary of UniProt entry ZIC5_HUMAN (Q96T25).

Description: Zinc finger protein ZIC 5
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 663 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 27 28
disorder n/a 33 44
disorder n/a 51 65
disorder n/a 67 248
low_complexity n/a 110 133
low_complexity n/a 137 174
low_complexity n/a 176 194
low_complexity n/a 205 215
low_complexity n/a 226 239
disorder n/a 252 284
low_complexity n/a 286 294
disorder n/a 297 305
disorder n/a 307 312
low_complexity n/a 311 330
low_complexity n/a 336 383
disorder n/a 341 384
disorder n/a 403 435
low_complexity n/a 410 424
Pfam zf_ZIC 422 453
disorder n/a 442 449
Pfam zf-C2H2 491 515
disorder n/a 506 511
disorder n/a 536 541
Pfam zf-C2H2 551 575
disorder n/a 569 614
low_complexity n/a 578 592
disorder n/a 631 632
disorder n/a 634 661

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q96T25. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MFLKAGRGNK VPPVRVYGPD CVVLMEPPLS KRNPPALRLA DLATAQVQPL
50
51
QNMTGFPALA GPPAHSQLRA AVAHLRLRDL GADPGVATTP LGPEHMAQAS
100
101
TLGLSPPSQA FPAHPEAPAA AARAAALVAH PGAGSYPCGG GSSGAQPSAP
150
151
PPPAPPLPPT PSPPPPPPPP PPPALSGYTT TNSGGGGSSG KGHSRDFVLR
200
201
RDLSATAPAA AMHGAPLGGE QRSGTGSPQH PAPPPHSAGM FISASGTYAG
250
251
PDGSGGPALF PALHDTPGAP GGHPHPLNGQ MRLGLAAAAA AAAAELYGRA
300
301
EPPFAPRSGD AHYGAVAAAA AAALHGYGAV NLNLNLAAAA AAAAAGPGPH
350
351
LQHHAPPPAP PPPPAPAQHP HQHHPHLPGA AGAFLRYMRQ PIKQELICKW
400
401
IDPDELAGLP PPPPPPPPPP PPPPAGGAKP CSKTFGTMHE LVNHVTVEHV
450
451
GGPEQSSHVC FWEDCPREGK PFKAKYKLIN HIRVHTGEKP FPCPFPGCGK
500
501
VFARSENLKI HKRTHTGEKP FKCEFDGCDR KFANSSDRKK HSHVHTSDKP
550
551
YYCKIRGCDK SYTHPSSLRK HMKIHCKSPP PSPGPLGYSS VGTPVGAPLS
600
601
PVLDPARSHS STLSPQVTNL NEWYVCQASG APSHLHTPSS NGTTSETEDE
650
651
EIYGNPEVVR TIH                                        
663
 

Show the unformatted sequence.

Checksums:
CRC64:90C16FF2EEB1F54A
MD5:84402df34d87f7707a135fec24ec1bcc

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;