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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: NPAS2_HUMAN (Q99743)

Summary

This is the summary of UniProt entry NPAS2_HUMAN (Q99743).

Description: Neuronal PAS domain-containing protein 2
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 824 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 17
Pfam HLH 10 60
Pfam PAS 84 176
Pfam PAS_11 248 356
disorder n/a 361 362
disorder n/a 364 383
disorder n/a 385 487
low_complexity n/a 405 420
low_complexity n/a 475 488
disorder n/a 496 497
coiled_coil n/a 506 526
disorder n/a 555 588
low_complexity n/a 559 576
disorder n/a 590 593
disorder n/a 600 824
low_complexity n/a 614 636
low_complexity n/a 739 760
low_complexity n/a 794 823

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q99743. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDEDEKDRAK RASRNKSEKK RRDQFNVLIK ELSSMLPGNT RKMDKTTVLE
50
51
KVIGFLQKHN EVSAQTEICD IQQDWKPSFL SNEEFTQLML EALDGFIIAV
100
101
TTDGSIIYVS DSITPLLGHL PSDVMDQNLL NFLPEQEHSE VYKILSSHML
150
151
VTDSPSPEYL KSDSDLEFYC HLLRGSLNPK EFPTYEYIKF VGNFRSYNNV
200
201
PSPSCNGFDN TLSRPCRVPL GKEVCFIATV RLATPQFLKE MCIVDEPLEE
250
251
FTSRHSLEWK FLFLDHRAPP IIGYLPFEVL GTSGYDYYHI DDLELLARCH
300
301
QHLMQFGKGK SCCYRFLTKG QQWIWLQTHY YITYHQWNSK PEFIVCTHSV
350
351
VSYADVRVER RQELALEDPP SEALHSSALK DKGSSLEPRQ HFNTLDVGAS
400
401
GLNTSHSPSA SSRSSHKSSH TAMSEPTSTP TKLMAEASTP ALPRSATLPQ
450
451
ELPVPGLSQA ATMPAPLPSP SSCDLTQQLL PQTVLQSTPA PMAQFSAQFS
500
501
MFQTIKDQLE QRTRILQANI RWQQEELHKI QEQLCLVQDS NVQMFLQQPA
550
551
VSLSFSSTQR PEAQQQLQQR SAAVTQPQLG AGPQLPGQIS SAQVTSQHLL
600
601
RESSVISTQG PKPMRSSQLM QSSGRSGSSL VSPFSSATAA LPPSLNLTTP
650
651
ASTSQDASQC QPSPDFSHDR QLRLLLSQPI QPMMPGSCDA RQPSEVSRTG
700
701
RQVKYAQSQT VFQNPDAHPA NSSSAPMPVL LMGQAVLHPS FPASQPSPLQ
750
751
PAQARQQPPQ HYLQVQAPTS LHSEQQDSLL LSTYSQQPGT LGYPQPPPAQ
800
801
PQPLRPPRRV SSLSESSGLQ QPPR                            
824
 

Show the unformatted sequence.

Checksums:
CRC64:679919FCDD3AFDEB
MD5:68b97923e3483a1092dc2186bc5ee176

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.