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7  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: SRXN1_HUMAN (Q9BYN0)

Summary

This is the summary of UniProt entry SRXN1_HUMAN (Q9BYN0).

Description: Sulfiredoxin-1 EC=1.8.98.2
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 137 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
low_complexity n/a 2 31
disorder n/a 8 32
Pfam ParBc 42 133
disorder n/a 67 69

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9BYN0. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MGLRAGGTLG RAGAGRGAPE GPGPSGGAQG GSIHSGRIAA VHNVPLSVLI
50
51
RPLPSVLDPA KVQSLVDTIR EDPDSVPPID VLWIKGAQGG DYFYSFGGCH
100
101
RYAAYQQLQR ETIPAKLVQS TLSDLRVYLG ASTPDLQ              
137
 

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Checksums:
CRC64:44F2C4256E5574D0
MD5:44e095f91832aa989321e2d2115dc94a

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
ParBc 42 - 133 1XW3 A 42 - 133 NGL View in InterPro
1XW4 X 42 - 133 NGL View in InterPro
1YZS A 42 - 133 NGL View in InterPro
2B6F A 42 - 133 NGL View in InterPro
2RII X 42 - 133 NGL View in InterPro
Y 42 - 133 NGL View in InterPro
3CYI A 42 - 133 NGL View in InterPro
3HY2 X 42 - 133 NGL View in InterPro
Y 42 - 133 NGL View in InterPro
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TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.