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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: POLH_MOUSE (Q9JJN0)

Summary

This is the summary of UniProt entry POLH_MOUSE (Q9JJN0).

Description: DNA polymerase eta
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
Length: 694 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam IMS 12 227
disorder n/a 157 159
low_complexity n/a 170 181
Pfam IMS_C 315 439
disorder n/a 315 317
low_complexity n/a 334 351
low_complexity n/a 375 384
disorder n/a 453 471
disorder n/a 494 502
disorder n/a 511 514
low_complexity n/a 515 529
disorder n/a 537 607
low_complexity n/a 540 561
Pfam zf_UBZ 612 643
disorder n/a 649 686
disorder n/a 688 689

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9JJN0. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAPGQNRVVA LVDMDCFFVQ VEQRQNPHLR NKPCAVVQYK SWKGGGIIAV
50
51
SYEARAFGVT RNMWADDAKK LCPDLLLAQV RESRGKANLT KYREASVEVM
100
101
EIMSYFAVIE RASIDEAYID LTSAVQERLQ KLQGQPISAD LLPSTYIEGL
150
151
PRGPTVEETV QKEAIRKQGL LQWLDSLQSD DPTSPDLRLT VGAMIVEEMR
200
201
AAIESKTGFQ CSAGISHNKV LAKLACGLNK PNRQTLVSHG SVPQLFSQMP
250
251
IRKIRSLGGK LGASVIEVLG IEYMGDLTQF TESQLQSHFG EKNGSWLYAM
300
301
CRGIEHDPVK PRQLPKTIGC SKNFPGKTAL ATREQVQWWL LQLALELEER
350
351
LTKDRNDNDR VATQLVVSIR FQGDRRLSSL RRCCALPRYD AHKMSQDAFA
400
401
AIRNCNTSGI QTEWSPPLTM LFLCATKFSA AAPPACTDIT AFLSSDSSCQ
450
451
PKVPIASSET RTQGSGPAVP TSKEAATSLA SFFQKAAKKQ RMKETSFVPL
500
501
NTATEKLSSK PSLVFQSSQT TGSQSFFKQK SLLLQHTQLS NSAAPDPPQA
550
551
SPAAQPSCLP AECVDSGPDD GAVKPVSSKA VSTEMNVAGD SPNVLDSPAY
600
601
NSQEVTQRAT EDQVLCEKCD SLVPVWDMPE HTDYHFALEL QKSFLQPCTS
650
651
KPQAIPAVSP QGKRNPKSPS ASSSKRLRPH GMQTLESFFK PLTH      
694
 

Show the unformatted sequence.

Checksums:
CRC64:727895AB5DB84BC8
MD5:81726688e403386b91e47835f7c83acc

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;