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3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: PNRC2_HUMAN (Q9NPJ4)

Summary

This is the summary of UniProt entry PNRC2_HUMAN (Q9NPJ4).

Description: Proline-rich nuclear receptor coactivator 2
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 139 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 82
disorder n/a 85 86
disorder n/a 89 119
Pfam PNRC 93 112
low_complexity n/a 99 112

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9NPJ4. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MGGGERYNIP APQSRNVSKN QQQLNRQKTK EQNSQMKIVH KKKERGHGYN
50
51
SSAAAWQAMQ NGGKNKNFPN NQSWNSSLSG PRLLFKSQAN QNYAGAKFSE
100
101
PPSPSVLPKP PSHWVPVSFN PSDKEIMTFQ LKTLLKVQV            
139
 

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Checksums:
CRC64:072039CB52551F90
MD5:9a649021248f7be5f6e528f13a3b938e

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
PNRC 100 - 112 5KQ1 C 100 - 112 NGL View in InterPro
5KQ4 F 100 - 112 NGL View in InterPro
101 - 112 5KQ1 F 101 - 112 NGL View in InterPro
102 - 112 4B6H C 102 - 112 NGL View in InterPro
D 102 - 112 NGL View in InterPro
99 - 112 5KQ4 C 99 - 112 NGL View in InterPro
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TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.