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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: FETUB_HUMAN (Q9UGM5)

Summary

This is the summary of UniProt entry FETUB_HUMAN (Q9UGM5).

Description: Fetuin-B
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 382 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
sig_p n/a 1 25
low_complexity n/a 3 16
Pfam Cystatin 32 125
Pfam Cystatin 154 246
low_complexity n/a 219 231
disorder n/a 263 332
disorder n/a 339 343
disorder n/a 355 382

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9UGM5. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MGLLLPLALC ILVLCCGAMS PPQLALNPSA LLSRGCNDSD VLAVAGFALR
50
51
DINKDRKDGY VLRLNRVNDA QEYRRGGLGS LFYLTLDVLE TDCHVLRKKA
100
101
WQDCGMRIFF ESVYGQCKAI FYMNNPSRVL YLAAYNCTLR PVSKKKIYMT
150
151
CPDCPSSIPT DSSNHQVLEA ATESLAKYNN ENTSKQYSLF KVTRASSQWV
200
201
VGPSYFVEYL IKESPCTKSQ ASSCSLQSSD SVPVGLCKGS LTRTHWEKFV
250
251
SVTCDFFESQ APATGSENSA VNQKPTNLPK VEESQQKNTP PTDSPSKAGP
300
301
RGSVQYLPDL DDKNSQEKGP QEAFPVHLDL TTNPQGETLD ISFLFLEPME
350
351
EKLVVLPFPK EKARTAECPG PAQNASPLVL PP                   
382
 

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Checksums:
CRC64:C73977793A30AF8A
MD5:2189a3a67ac25db7297a2ab1cf6228da

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Cystatin 154 - 246 6SAZ B 154 - 246 NGL View in InterPro
D 154 - 246 NGL View in InterPro
32 - 125 6SAZ B 32 - 125 NGL View in InterPro
D 32 - 125 NGL View in InterPro
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The parts of the structure corresponding to the Pfam family are highlighted in yellow.

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TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.