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56  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: DPOLL_HUMAN (Q9UGP5)

Summary

This is the summary of UniProt entry DPOLL_HUMAN (Q9UGP5).

Description: DNA polymerase lambda {ECO:0000305}
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 575 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
disorder n/a 27 28
low_complexity n/a 32 39
disorder n/a 77 79
low_complexity n/a 93 109
disorder n/a 143 211
low_complexity n/a 168 179
disorder n/a 220 228
disorder n/a 238 242
disorder n/a 250 254
Pfam HHH_8 253 318
Pfam DNA_pol_lambd_f 336 384
Pfam DNA_pol_B_palm 386 496
disorder n/a 394 398
disorder n/a 473 475
low_complexity n/a 478 489
Pfam DNA_pol_B_thumb 502 574
disorder n/a 546 548

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9UGP5. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MDPRGILKAF PKRQKIHADA SSKVLAKIPR REEGEEAEEW LSSLRAHVVR
50
51
TGIGRARAEL FEKQIVQHGG QLCPAQGPGV THIVVDEGMD YERALRLLRL
100
101
PQLPPGAQLV KSAWLSLCLQ ERRLVDVAGF SIFIPSRYLD HPQPSKAEQD
150
151
ASIPPGTHEA LLQTALSPPP PPTRPVSPPQ KAKEAPNTQA QPISDDEASD
200
201
GEETQVSAAD LEALISGHYP TSLEGDCEPS PAPAVLDKWV CAQPSSQKAT
250
251
NHNLHITEKL EVLAKAYSVQ GDKWRALGYA KAINALKSFH KPVTSYQEAC
300
301
SIPGIGKRMA EKIIEILESG HLRKLDHISE SVPVLELFSN IWGAGTKTAQ
350
351
MWYQQGFRSL EDIRSQASLT TQQAIGLKHY SDFLERMPRE EATEIEQTVQ
400
401
KAAQAFNSGL LCVACGSYRR GKATCGDVDV LITHPDGRSH RGIFSRLLDS
450
451
LRQEGFLTDD LVSQEENGQQ QKYLGVCRLP GPGRRHRRLD IIVVPYSEFA
500
501
CALLYFTGSA HFNRSMRALA KTKGMSLSEH ALSTAVVRNT HGCKVGPGRV
550
551
LPTPTEKDVF RLLGLPYREP AERDW                           
575
 

Show the unformatted sequence.

Checksums:
CRC64:FD9196A1C94923C4
MD5:c120becf7108838ff7988a98dd572fe1

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
DNA_pol_B_palm 386 - 496 1RZT A 386 - 496 Show 3D Structure View in InterPro
E 386 - 496 Show 3D Structure View in InterPro
I 386 - 496 Show 3D Structure View in InterPro
M 386 - 496 Show 3D Structure View in InterPro
1XSL A 386 - 496 Show 3D Structure View in InterPro
E 386 - 496 Show 3D Structure View in InterPro
I 386 - 496 Show 3D Structure View in InterPro
M 386 - 496 Show 3D Structure View in InterPro
1XSN A 386 - 496 Show 3D Structure View in InterPro
1XSP A 386 - 496 Show 3D Structure View in InterPro
2BCQ A 386 - 496 Show 3D Structure View in InterPro
2BCR A 386 - 496 Show 3D Structure View in InterPro
2BCS A 386 - 496 Show 3D Structure View in InterPro
2BCU A 386 - 496 Show 3D Structure View in InterPro
2BCV A 386 - 496 Show 3D Structure View in InterPro
2GWS A 386 - 496 Show 3D Structure View in InterPro
E 386 - 496 Show 3D Structure View in InterPro
I 386 - 496 Show 3D Structure View in InterPro
M 386 - 496 Show 3D Structure View in InterPro
2PFN A 386 - 496 Show 3D Structure View in InterPro
2PFO A 386 - 496 Show 3D Structure View in InterPro
2PFP A 386 - 496 Show 3D Structure View in InterPro
2PFQ A 386 - 496 Show 3D Structure View in InterPro
3C5F A 386 - 496 Show 3D Structure View in InterPro
B 386 - 496 Show 3D Structure View in InterPro
3C5G A 386 - 496 Show 3D Structure View in InterPro
B 386 - 496 Show 3D Structure View in InterPro
3HW8 A 386 - 496 Show 3D Structure View in InterPro
3HWT A 386 - 496 Show 3D Structure View in InterPro
3HX0 A 386 - 496 Show 3D Structure View in InterPro
F 386 - 496 Show 3D Structure View in InterPro
K 386 - 496 Show 3D Structure View in InterPro
P 386 - 496 Show 3D Structure View in InterPro
3MDA A 386 - 496 Show 3D Structure View in InterPro
3MDC A 386 - 496 Show 3D Structure View in InterPro
3MGH A 386 - 496 Show 3D Structure View in InterPro
C 386 - 496 Show 3D Structure View in InterPro
3MGI A 386 - 496 Show 3D Structure View in InterPro
3PML A 386 - 496 Show 3D Structure View in InterPro
B 386 - 496 Show 3D Structure View in InterPro
3PMN A 386 - 496 Show 3D Structure View in InterPro
3PNC A 386 - 496 Show 3D Structure View in InterPro
3UPQ A 386 - 496 Show 3D Structure View in InterPro
3UQ0 A 386 - 496 Show 3D Structure View in InterPro
3UQ2 A 386 - 496 Show 3D Structure View in InterPro
4FO6 A 386 - 496 Show 3D Structure View in InterPro
4K4G A 386 - 496 Show 3D Structure View in InterPro
E 386 - 496 Show 3D Structure View in InterPro
I 386 - 496 Show 3D Structure View in InterPro
M 386 - 496 Show 3D Structure View in InterPro
4K4H A 386 - 496 Show 3D Structure View in InterPro
E 386 - 496 Show 3D Structure View in InterPro
I 386 - 496 Show 3D Structure View in InterPro
M 386 - 496 Show 3D Structure View in InterPro
4K4I A 386 - 496 Show 3D Structure View in InterPro
E 386 - 496 Show 3D Structure View in InterPro
I 386 - 496 Show 3D Structure View in InterPro
M 386 - 496 Show 3D Structure View in InterPro
4X5V A 386 - 496 Show 3D Structure View in InterPro
4XA5 A 386 - 496 Show 3D Structure View in InterPro
4XQ8 A 386 - 496 Show 3D Structure View in InterPro
B 386 - 496 Show 3D Structure View in InterPro
4XRH A 386 - 496 Show 3D Structure View in InterPro
B 386 - 496 Show 3D Structure View in InterPro
4XUS A 386 - 496 Show 3D Structure View in InterPro
5CA7 A 386 - 496 Show 3D Structure View in InterPro
B 386 - 496 Show 3D Structure View in InterPro
5CB1 A 386 - 496 Show 3D Structure View in InterPro
B 386 - 496 Show 3D Structure View in InterPro
5CHG A 386 - 496 Show 3D Structure View in InterPro
B 386 - 496 Show 3D Structure View in InterPro
5CJ7 A 386 - 496 Show 3D Structure View in InterPro
B 386 - 496 Show 3D Structure View in InterPro
5CP2 A 386 - 496 Show 3D Structure View in InterPro
B 386 - 496 Show 3D Structure View in InterPro
5CR0 A 386 - 496 Show 3D Structure View in InterPro
B 386 - 496 Show 3D Structure View in InterPro
5CWR A 386 - 496 Show 3D Structure View in InterPro
B 386 - 496 Show 3D Structure View in InterPro
5DDM A 386 - 496 Show 3D Structure View in InterPro
B 386 - 496 Show 3D Structure View in InterPro
5DDY A 386 - 496 Show 3D Structure View in InterPro
C 386 - 496 Show 3D Structure View in InterPro
E 386 - 496 Show 3D Structure View in InterPro
G 386 - 496 Show 3D Structure View in InterPro
5DKW A 386 - 496 Show 3D Structure View in InterPro
B 386 - 496 Show 3D Structure View in InterPro
5III A 386 - 496 Show 3D Structure View in InterPro
5IIJ A 386 - 496 Show 3D Structure View in InterPro
5IIK A 386 - 496 Show 3D Structure View in InterPro
5IIL A 386 - 496 Show 3D Structure View in InterPro
5IIM A 386 - 496 Show 3D Structure View in InterPro
5IIN A 386 - 496 Show 3D Structure View in InterPro
5IIO A 386 - 496 Show 3D Structure View in InterPro
E 386 - 496 Show 3D Structure View in InterPro
I 386 - 496 Show 3D Structure View in InterPro
M 386 - 496 Show 3D Structure View in InterPro
DNA_pol_B_thumb 502 - 574 1RZT A 502 - 574 Show 3D Structure View in InterPro
E 502 - 574 Show 3D Structure View in InterPro
I 502 - 574 Show 3D Structure View in InterPro
M 502 - 574 Show 3D Structure View in InterPro
1XSL A 502 - 574 Show 3D Structure View in InterPro
E 502 - 574 Show 3D Structure View in InterPro
I 502 - 574 Show 3D Structure View in InterPro
M 502 - 574 Show 3D Structure View in InterPro
1XSN A 502 - 574 Show 3D Structure View in InterPro
1XSP A 502 - 574 Show 3D Structure View in InterPro
2BCQ A 502 - 574 Show 3D Structure View in InterPro
2BCR A 502 - 574 Show 3D Structure View in InterPro
2BCS A 502 - 574 Show 3D Structure View in InterPro
2BCU A 502 - 574 Show 3D Structure View in InterPro
2BCV A 502 - 574 Show 3D Structure View in InterPro
2GWS A 502 - 574 Show 3D Structure View in InterPro
E 502 - 574 Show 3D Structure View in InterPro
I 502 - 574 Show 3D Structure View in InterPro
M 502 - 574 Show 3D Structure View in InterPro
2PFN A 502 - 574 Show 3D Structure View in InterPro
2PFO A 502 - 574 Show 3D Structure View in InterPro
2PFP A 502 - 574 Show 3D Structure View in InterPro
2PFQ A 502 - 574 Show 3D Structure View in InterPro
3C5F A 502 - 574 Show 3D Structure View in InterPro
B 502 - 574 Show 3D Structure View in InterPro
3C5G A 502 - 574 Show 3D Structure View in InterPro
B 502 - 574 Show 3D Structure View in InterPro
3HW8 A 502 - 574 Show 3D Structure View in InterPro
3HWT A 502 - 574 Show 3D Structure View in InterPro
3HX0 A 502 - 574 Show 3D Structure View in InterPro
F 502 - 574 Show 3D Structure View in InterPro
K 502 - 574 Show 3D Structure View in InterPro
P 502 - 574 Show 3D Structure View in InterPro
3MDA A 502 - 574 Show 3D Structure View in InterPro
3MDC A 502 - 574 Show 3D Structure View in InterPro
3MGH A 502 - 574 Show 3D Structure View in InterPro
C 502 - 574 Show 3D Structure View in InterPro
3MGI A 502 - 574 Show 3D Structure View in InterPro
3PML A 502 - 574 Show 3D Structure View in InterPro
B 502 - 574 Show 3D Structure View in InterPro
3PMN A 502 - 574 Show 3D Structure View in InterPro
3PNC A 502 - 574 Show 3D Structure View in InterPro
3UPQ A 502 - 574 Show 3D Structure View in InterPro
3UQ0 A 502 - 574 Show 3D Structure View in InterPro
3UQ2 A 502 - 574 Show 3D Structure View in InterPro
4FO6 A 502 - 574 Show 3D Structure View in InterPro
4K4G A 502 - 574 Show 3D Structure View in InterPro
E 502 - 574 Show 3D Structure View in InterPro
I 502 - 574 Show 3D Structure View in InterPro
M 502 - 574 Show 3D Structure View in InterPro
4K4H A 502 - 574 Show 3D Structure View in InterPro
E 502 - 574 Show 3D Structure View in InterPro
I 502 - 574 Show 3D Structure View in InterPro
M 502 - 574 Show 3D Structure View in InterPro
4K4I A 502 - 574 Show 3D Structure View in InterPro
E 502 - 574 Show 3D Structure View in InterPro
I 502 - 574 Show 3D Structure View in InterPro
M 502 - 574 Show 3D Structure View in InterPro
4X5V A 502 - 574 Show 3D Structure View in InterPro
4XA5 A 502 - 574 Show 3D Structure View in InterPro
4XQ8 A 502 - 574 Show 3D Structure View in InterPro
B 502 - 574 Show 3D Structure View in InterPro
4XRH A 502 - 574 Show 3D Structure View in InterPro
B 502 - 574 Show 3D Structure View in InterPro
4XUS A 502 - 574 Show 3D Structure View in InterPro
5CA7 A 502 - 574 Show 3D Structure View in InterPro
B 502 - 574 Show 3D Structure View in InterPro
5CB1 A 502 - 574 Show 3D Structure View in InterPro
B 502 - 574 Show 3D Structure View in InterPro
5CHG A 502 - 574 Show 3D Structure View in InterPro
B 502 - 574 Show 3D Structure View in InterPro
5CJ7 A 502 - 574 Show 3D Structure View in InterPro
B 502 - 574 Show 3D Structure View in InterPro
5CP2 A 502 - 574 Show 3D Structure View in InterPro
B 502 - 574 Show 3D Structure View in InterPro
5CR0 A 502 - 574 Show 3D Structure View in InterPro
B 502 - 574 Show 3D Structure View in InterPro
5CWR A 502 - 574 Show 3D Structure View in InterPro
B 502 - 574 Show 3D Structure View in InterPro
5DDM A 502 - 574 Show 3D Structure View in InterPro
B 502 - 574 Show 3D Structure View in InterPro
5DDY A 502 - 574 Show 3D Structure View in InterPro
C 502 - 574 Show 3D Structure View in InterPro
E 502 - 574 Show 3D Structure View in InterPro
G 502 - 574 Show 3D Structure View in InterPro
5DKW A 502 - 574 Show 3D Structure View in InterPro
B 502 - 574 Show 3D Structure View in InterPro
5III A 502 - 574 Show 3D Structure View in InterPro
5IIJ A 502 - 574 Show 3D Structure View in InterPro
5IIK A 502 - 574 Show 3D Structure View in InterPro
5IIL A 502 - 574 Show 3D Structure View in InterPro
5IIM A 502 - 574 Show 3D Structure View in InterPro
5IIN A 502 - 574 Show 3D Structure View in InterPro
5IIO A 502 - 574 Show 3D Structure View in InterPro
E 502 - 574 Show 3D Structure View in InterPro
I 502 - 574 Show 3D Structure View in InterPro
M 502 - 574 Show 3D Structure View in InterPro
DNA_pol_lambd_f 336 - 384 1RZT A 336 - 384 Show 3D Structure View in InterPro
E 336 - 384 Show 3D Structure View in InterPro
I 336 - 384 Show 3D Structure View in InterPro
M 336 - 384 Show 3D Structure View in InterPro
1XSL A 336 - 384 Show 3D Structure View in InterPro
E 336 - 384 Show 3D Structure View in InterPro
I 336 - 384 Show 3D Structure View in InterPro
M 336 - 384 Show 3D Structure View in InterPro
1XSN A 336 - 384 Show 3D Structure View in InterPro
1XSP A 336 - 384 Show 3D Structure View in InterPro
2BCQ A 336 - 384 Show 3D Structure View in InterPro
2BCR A 336 - 384 Show 3D Structure View in InterPro
2BCS A 336 - 384 Show 3D Structure View in InterPro
2BCU A 336 - 384 Show 3D Structure View in InterPro
2BCV A 336 - 384 Show 3D Structure View in InterPro
2GWS A 336 - 384 Show 3D Structure View in InterPro
E 336 - 384 Show 3D Structure View in InterPro
I 336 - 384 Show 3D Structure View in InterPro
M 336 - 384 Show 3D Structure View in InterPro
2PFN A 336 - 384 Show 3D Structure View in InterPro
2PFO A 336 - 384 Show 3D Structure View in InterPro
2PFP A 336 - 384 Show 3D Structure View in InterPro
2PFQ A 336 - 384 Show 3D Structure View in InterPro
3C5F A 336 - 384 Show 3D Structure View in InterPro
B 336 - 384 Show 3D Structure View in InterPro
3C5G A 336 - 384 Show 3D Structure View in InterPro
B 336 - 384 Show 3D Structure View in InterPro
3HW8 A 336 - 384 Show 3D Structure View in InterPro
3HWT A 336 - 384 Show 3D Structure View in InterPro
3HX0 A 336 - 384 Show 3D Structure View in InterPro
F 336 - 384 Show 3D Structure View in InterPro
K 336 - 384 Show 3D Structure View in InterPro
P 336 - 384 Show 3D Structure View in InterPro
3MDA A 336 - 384 Show 3D Structure View in InterPro
3MDC A 336 - 384 Show 3D Structure View in InterPro
3MGH A 336 - 384 Show 3D Structure View in InterPro
C 336 - 384 Show 3D Structure View in InterPro
3MGI A 336 - 384 Show 3D Structure View in InterPro
3PML A 336 - 384 Show 3D Structure View in InterPro
B 336 - 384 Show 3D Structure View in InterPro
3PMN A 336 - 384 Show 3D Structure View in InterPro
3PNC A 336 - 384 Show 3D Structure View in InterPro
3UPQ A 336 - 384 Show 3D Structure View in InterPro
3UQ0 A 336 - 384 Show 3D Structure View in InterPro
3UQ2 A 336 - 384 Show 3D Structure View in InterPro
4FO6 A 336 - 384 Show 3D Structure View in InterPro
4K4G A 336 - 384 Show 3D Structure View in InterPro
E 336 - 384 Show 3D Structure View in InterPro
I 336 - 384 Show 3D Structure View in InterPro
M 336 - 384 Show 3D Structure View in InterPro
4K4H A 336 - 384 Show 3D Structure View in InterPro
E 336 - 384 Show 3D Structure View in InterPro
I 336 - 384 Show 3D Structure View in InterPro
M 336 - 384 Show 3D Structure View in InterPro
4K4I A 336 - 384 Show 3D Structure View in InterPro
E 336 - 384 Show 3D Structure View in InterPro
I 336 - 384 Show 3D Structure View in InterPro
M 336 - 384 Show 3D Structure View in InterPro
4X5V A 336 - 384 Show 3D Structure View in InterPro
4XA5 A 336 - 384 Show 3D Structure View in InterPro
4XQ8 A 336 - 384 Show 3D Structure View in InterPro
B 336 - 384 Show 3D Structure View in InterPro
4XRH A 336 - 384 Show 3D Structure View in InterPro
B 336 - 384 Show 3D Structure View in InterPro
4XUS A 336 - 384 Show 3D Structure View in InterPro
5CA7 A 336 - 384 Show 3D Structure View in InterPro
B 336 - 384 Show 3D Structure View in InterPro
5CB1 A 336 - 384 Show 3D Structure View in InterPro
B 336 - 384 Show 3D Structure View in InterPro
5CHG A 336 - 384 Show 3D Structure View in InterPro
B 336 - 384 Show 3D Structure View in InterPro
5CJ7 A 336 - 384 Show 3D Structure View in InterPro
B 336 - 384 Show 3D Structure View in InterPro
5CP2 A 336 - 384 Show 3D Structure View in InterPro
B 336 - 384 Show 3D Structure View in InterPro
5CR0 A 336 - 384 Show 3D Structure View in InterPro
B 336 - 384 Show 3D Structure View in InterPro
5CWR A 336 - 384 Show 3D Structure View in InterPro
B 336 - 384 Show 3D Structure View in InterPro
5DDM A 336 - 384 Show 3D Structure View in InterPro
B 336 - 384 Show 3D Structure View in InterPro
5DDY A 336 - 384 Show 3D Structure View in InterPro
C 336 - 384 Show 3D Structure View in InterPro
E 336 - 384 Show 3D Structure View in InterPro
G 336 - 384 Show 3D Structure View in InterPro
5DKW A 336 - 384 Show 3D Structure View in InterPro
B 336 - 384 Show 3D Structure View in InterPro
5III A 336 - 384 Show 3D Structure View in InterPro
5IIJ A 336 - 384 Show 3D Structure View in InterPro
5IIK A 336 - 384 Show 3D Structure View in InterPro
5IIL A 336 - 384 Show 3D Structure View in InterPro
5IIM A 336 - 384 Show 3D Structure View in InterPro
5IIN A 336 - 384 Show 3D Structure View in InterPro
5IIO A 336 - 384 Show 3D Structure View in InterPro
E 336 - 384 Show 3D Structure View in InterPro
I 336 - 384 Show 3D Structure View in InterPro
M 336 - 384 Show 3D Structure View in InterPro
HHH_8 253 - 318 1NZP A 253 - 318 Show 3D Structure View in InterPro
1RZT A 253 - 318 Show 3D Structure View in InterPro
E 253 - 318 Show 3D Structure View in InterPro
I 253 - 318 Show 3D Structure View in InterPro
M 253 - 318 Show 3D Structure View in InterPro
1XSL A 253 - 318 Show 3D Structure View in InterPro
E 253 - 318 Show 3D Structure View in InterPro
I 253 - 318 Show 3D Structure View in InterPro
M 253 - 318 Show 3D Structure View in InterPro
1XSN A 253 - 318 Show 3D Structure View in InterPro
1XSP A 253 - 318 Show 3D Structure View in InterPro
2BCQ A 253 - 318 Show 3D Structure View in InterPro
2BCR A 253 - 318 Show 3D Structure View in InterPro
2BCS A 253 - 318 Show 3D Structure View in InterPro
2BCU A 253 - 318 Show 3D Structure View in InterPro
2BCV A 253 - 318 Show 3D Structure View in InterPro
2GWS A 253 - 318 Show 3D Structure View in InterPro
E 253 - 318 Show 3D Structure View in InterPro
I 253 - 318 Show 3D Structure View in InterPro
M 253 - 318 Show 3D Structure View in InterPro
2PFN A 253 - 318 Show 3D Structure View in InterPro
2PFO A 253 - 318 Show 3D Structure View in InterPro
2PFP A 253 - 318 Show 3D Structure View in InterPro
2PFQ A 253 - 318 Show 3D Structure View in InterPro
3C5F A 253 - 318 Show 3D Structure View in InterPro
B 253 - 318 Show 3D Structure View in InterPro
3C5G A 253 - 318 Show 3D Structure View in InterPro
B 253 - 318 Show 3D Structure View in InterPro
3HW8 A 253 - 318 Show 3D Structure View in InterPro
3HX0 A 253 - 318 Show 3D Structure View in InterPro
F 253 - 318 Show 3D Structure View in InterPro
K 253 - 318 Show 3D Structure View in InterPro
P 253 - 318 Show 3D Structure View in InterPro
3MDA A 253 - 318 Show 3D Structure View in InterPro
3MGH A 253 - 318 Show 3D Structure View in InterPro
C 253 - 318 Show 3D Structure View in InterPro
3MGI A 253 - 318 Show 3D Structure View in InterPro
3PML A 253 - 318 Show 3D Structure View in InterPro
B 253 - 318 Show 3D Structure View in InterPro
3PMN A 253 - 318 Show 3D Structure View in InterPro
3PNC A 253 - 318 Show 3D Structure View in InterPro
3UPQ A 253 - 318 Show 3D Structure View in InterPro
3UQ0 A 253 - 318 Show 3D Structure View in InterPro
3UQ2 A 253 - 318 Show 3D Structure View in InterPro
4FO6 A 253 - 318 Show 3D Structure View in InterPro
4K4G A 253 - 318 Show 3D Structure View in InterPro
E 253 - 318 Show 3D Structure View in InterPro
I 253 - 318 Show 3D Structure View in InterPro
M 253 - 318 Show 3D Structure View in InterPro
4K4H A 253 - 318 Show 3D Structure View in InterPro
E 253 - 318 Show 3D Structure View in InterPro
I 253 - 318 Show 3D Structure View in InterPro
M 253 - 318 Show 3D Structure View in InterPro
4K4I A 253 - 318 Show 3D Structure View in InterPro
E 253 - 318 Show 3D Structure View in InterPro
I 253 - 318 Show 3D Structure View in InterPro
M 253 - 318 Show 3D Structure View in InterPro
4X5V A 253 - 318 Show 3D Structure View in InterPro
4XA5 A 253 - 318 Show 3D Structure View in InterPro
4XUS A 253 - 318 Show 3D Structure View in InterPro
5CB1 A 253 - 318 Show 3D Structure View in InterPro
5CWR A 253 - 318 Show 3D Structure View in InterPro
B 253 - 318 Show 3D Structure View in InterPro
5DDY A 253 - 318 Show 3D Structure View in InterPro
C 253 - 318 Show 3D Structure View in InterPro
5DKW A 253 - 318 Show 3D Structure View in InterPro
B 253 - 318 Show 3D Structure View in InterPro
5III A 253 - 318 Show 3D Structure View in InterPro
5IIJ A 253 - 318 Show 3D Structure View in InterPro
5IIK A 253 - 318 Show 3D Structure View in InterPro
5IIL A 253 - 318 Show 3D Structure View in InterPro
5IIM A 253 - 318 Show 3D Structure View in InterPro
5IIN A 253 - 318 Show 3D Structure View in InterPro
5IIO A 253 - 318 Show 3D Structure View in InterPro
E 253 - 318 Show 3D Structure View in InterPro
I 253 - 318 Show 3D Structure View in InterPro
M 253 - 318 Show 3D Structure View in InterPro
254 - 318 3MDC A 254 - 318 Show 3D Structure View in InterPro
257 - 318 3HWT A 257 - 318 Show 3D Structure View in InterPro
×

The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;