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12  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: ABC3B_HUMAN (Q9UH17)

Summary

This is the summary of UniProt entry ABC3B_HUMAN (Q9UH17).

Description: DNA dC->dU-editing enzyme APOBEC-3B EC=3.5.4.38
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 382 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
Pfam NAD2 10 189
Pfam APOBEC_C 301 377

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9UH17. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MNPQIRNPME RMYRDTFYDN FENEPILYGR SYTWLCYEVK IKRGRSNLLW
50
51
DTGVFRGQVY FKPQYHAEMC FLSWFCGNQL PAYKCFQITW FVSWTPCPDC
100
101
VAKLAEFLSE HPNVTLTISA ARLYYYWERD YRRALCRLSQ AGARVTIMDY
150
151
EEFAYCWENF VYNEGQQFMP WYKFDENYAF LHRTLKEILR YLMDPDTFTF
200
201
NFNNDPLVLR RRQTYLCYEV ERLDNGTWVL MDQHMGFLCN EAKNLLCGFY
250
251
GRHAELRFLD LVPSLQLDPA QIYRVTWFIS WSPCFSWGCA GEVRAFLQEN
300
301
THVRLRIFAA RIYDYDPLYK EALQMLRDAG AQVSIMTYDE FEYCWDTFVY
350
351
RQGCPFQPWD GLEEHSQALS GRLRAILQNQ GN                   
382
 

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Checksums:
CRC64:DA6EDD23E8856240
MD5:8bdedb5255f1d6baaa8b126bb5ac33d6

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
APOBEC_C 301 - 377 2NBQ A 301 - 377 NGL View in InterPro
5CQD A 301 - 377 NGL View in InterPro
C 301 - 377 NGL View in InterPro
5CQH A 301 - 377 NGL View in InterPro
5CQI A 301 - 377 NGL View in InterPro
5CQK A 301 - 377 NGL View in InterPro
5SXG A 301 - 377 NGL View in InterPro
B 301 - 377 NGL View in InterPro
5SXH A 301 - 377 NGL View in InterPro
B 301 - 377 NGL View in InterPro
5TD5 A 301 - 377 NGL View in InterPro
6NFK A 301 - 377 NGL View in InterPro
6NFL A 301 - 377 NGL View in InterPro
6NFM A 301 - 377 NGL View in InterPro
NAD2 10 - 189 5TKM A 10 - 189 NGL View in InterPro
B 10 - 189 NGL View in InterPro
187 - 189 2NBQ A 187 - 189 NGL View in InterPro
5CQD A 187 - 189 NGL View in InterPro
188 - 189 5CQD C 188 - 189 NGL View in InterPro
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TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.