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3  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: TRM6_HUMAN (Q9UJA5)

Summary

This is the summary of UniProt entry TRM6_HUMAN (Q9UJA5).

Description: tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 497 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
disorder n/a 1 23
low_complexity n/a 3 16
Pfam Gcd10p 19 322
disorder n/a 69 102
low_complexity n/a 145 154
disorder n/a 270 271
disorder n/a 276 361
low_complexity n/a 344 356
low_complexity n/a 444 456
disorder n/a 470 497

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9UJA5. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEGSGEQPGP QPQHPGDHRI RDGDFVVLKR EDVFKAVQVQ RRKKVTFEKQ
50
51
WFYLDNVIGH SYGTAFEVTS GGSLQPKKKR EEPTAETKEA GTDNRNIVDD
100
101
GKSQKLTQDD IKALKDKGIK GEEIVQQLIE NSTTFRDKTE FAQDKYIKKK
150
151
KKKYEAIITV VKPSTRILSI MYYAREPGKI NHMRYDTLAQ MLTLGNIRAG
200
201
NKMIVMETCA GLVLGAMMER MGGFGSIIQL YPGGGPVRAA TACFGFPKSF
250
251
LSGLYEFPLN KVDSLLHGTF SAKMLSSEPK DSALVEESNG TLEEKQASEQ
300
301
ENEDSMAEAP ESNHPEDQET METISQDPEH KGPKERGSKK DYIQEKQRRQ
350
351
EEQRKRHLEA AALLSERNAD GLIVASRFHP TPLLLSLLDF VAPSRPFVVY
400
401
CQYKEPLLEC YTKLRERGGV INLRLSETWL RNYQVLPDRS HPKLLMSGGG
450
451
GYLLSGFTVA MDNLKADTSL KSNASTLESH ETEEPAAKKR KCPESDS   
497
 

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Checksums:
CRC64:920800D0722A6CBB
MD5:d8fc8293bad09ddc134f8c7cfc03a5c4

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
Gcd10p 19 - 271 5CCB B 19 - 271 NGL View in InterPro
5CCX B 19 - 271 NGL View in InterPro
5CD1 B 19 - 271 NGL View in InterPro
E 19 - 271 NGL View in InterPro
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The parts of the structure corresponding to the Pfam family are highlighted in yellow.

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TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.