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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: SMAG1_HUMAN (Q9UPU9)

Summary

This is the summary of UniProt entry SMAG1_HUMAN (Q9UPU9).

Description: Protein Smaug homolog 1
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 718 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
low_complexity n/a 82 95
disorder n/a 155 165
disorder n/a 168 178
disorder n/a 180 191
disorder n/a 211 213
disorder n/a 215 220
disorder n/a 223 228
low_complexity n/a 227 241
disorder n/a 231 323
low_complexity n/a 292 305
Pfam SAM_1 321 381
disorder n/a 355 356
disorder n/a 360 361
disorder n/a 373 374
disorder n/a 415 473
low_complexity n/a 425 438
low_complexity n/a 453 470
disorder n/a 478 485
disorder n/a 487 488
disorder n/a 490 492
disorder n/a 567 569
disorder n/a 572 607
disorder n/a 620 691
disorder n/a 694 696
disorder n/a 698 700
disorder n/a 703 705
disorder n/a 710 718

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9UPU9. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MMFRDQVGVL AGWFKGWNEC EQTVALLSLL KRVSQTQARF LQLCLEHSLA
50
51
DCAELHVLER EANSPGIINQ WQQESKDKVI SLLLTHLPLL KPGNLDAKVE
100
101
YMKLLPKILA HSIEHNQHIE ESRQLLSYAL IHPATSLEDR SALAMWLNHL
150
151
EDRTSTSFGG QNRGRSDSVD YGQTHYYHQR QNSDDKLNGW QNSRDSGICI
200
201
NASNWQDKSM GCENGHVPLY SSSSVPTTIN TIGTSTSTIL SGQAHHSPLK
250
251
RSVSLTPPMN VPNQPLGHGW MSHEDLRARG PQCLPSDHAP LSPQSSVASS
300
301
GSGGSEHLED QTTARNTFQE EGSGMKDVPA WLKSLRLHKY AALFSQMTYE
350
351
EMMALTECQL EAQNVTKGAR HKIVISIQKL KERQNLLKSL ERDIIEGGSL
400
401
RIPLQELHQM ILTPIKAYSS PSTTPEARRR EPQAPRQPSL MGPESQSPDC
450
451
KDGAAATGAT ATPSAGASGG LQPHQLSSCD GELAVAPLPE GDLPGQFTRV
500
501
MGKVCTQLLV SRPDEENISS YLQLIDKCLI HEAFTETQKK RLLSWKQQVQ
550
551
KLFRSFPRKT LLDISGYRQQ RNRGFGQSNS LPTAGSVGGG MGRRNPRQYQ
600
601
IPSRNVPSAR LGLLGTSGFV SSNQRNTTAT PTIMKQGRQN LWFANPGGSN
650
651
SMPSRTHSSV QRTRSLPVHT SPQNMLMFQQ PEFQLPVTEP DINNRLESLC
700
701
LSMTEHALGD GVDRTSTI                                   
718
 

Show the unformatted sequence.

Checksums:
CRC64:01F5D49E6447F771
MD5:bfb7be77852b10d79b9405510181c1ae

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;