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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: DHDH_HUMAN (Q9UQ10)

Summary

This is the summary of UniProt entry DHDH_HUMAN (Q9UQ10).

Description: Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase EC=1.3.1.20 EC=1.1.1.179
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 334 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
Pfam GFO_IDH_MocA 3 123
low_complexity n/a 101 117
Pfam GFO_IDH_MocA_C 136 265
disorder n/a 200 202

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9UQ10. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MALRWGIVSV GLISSDFTAV LQTLPRSEHQ VVAVAARDLS RAKEFAQKHD
50
51
IPKAYGSYEE LAKDPSVEVA YIGTQHPQHK AAVMLCLAAG KAVLCEKPTG
100
101
VNAAEVREMV AEARSRALFL MEAIWTRFFP ASEALRSVLA QGTLGDLRVA
150
151
RAEFGKNLIH VPRAVDRAQA GGALLDIGIY CVQFTSMVFG GQKPEKISVV
200
201
GRRHETGVDD TVTVLLQYPG EVHGSFTCSI TVQLSNTASV SGTKGMVQLL
250
251
NPCWCPTELV VKGEHKEFPL PPVPKDCNFD NGAGMSYEAK HVWECLRKGM
300
301
KESPVIPLSE SELLADILEE VRKAIGVTFP QDKR                 
334
 

Show the unformatted sequence.

Checksums:
CRC64:1E2E11DF0B55214B
MD5:1bd16508c44a0c7037be97e91a6ef9e8

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;