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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: Q9W374_DROME (Q9W374)

Summary

This is the summary of UniProt entry Q9W374_DROME (Q9W374).

Description: Dihydropyrimidine dehydrogenase [NADP(+)] {ECO:0000256|RuleBase:RU364041}
Source organism: Drosophila melanogaster (Fruit fly) (NCBI taxonomy ID 7227)
Length: 1031 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 1 14
disorder n/a 29 32
disorder n/a 35 45
Pfam Fer4_20 57 170
disorder n/a 175 176
Pfam Pyr_redox_2 186 494
disorder n/a 413 416
disorder n/a 418 421
Pfam DHO_dh 527 833
low_complexity n/a 716 729
disorder n/a 756 757
disorder n/a 843 863
disorder n/a 902 918
low_complexity n/a 906 919
Pfam Fer4_21 946 1004

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9W374. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MSPPQLLSKD SPDIEDLLSL NPRVKTQCSV VPTKQTKENK KHWKRNADHA
50
51
APPCTTLAND FSDIKHTTLS ERGALEEAAR CLKCADAPCQ KSCPTQLDIK
100
101
SFITSIANKN FYGAAKAIFS DNPLGLTCGM VCPTSDLCVG GCNLQASEAG
150
151
PINIGGLQQF ATEVFKKMGV RQRRTPQAEA NPLSQKIALV GGGPASLSCA
200
201
TFLARLGYRD VTIYERRSYL GGLSAAEIPQ YRLPIDAVNF EIDLVRDLGV
250
251
RIETGRSLGT KDLTIQGLLS TGHDAVFVGI GLPEPKLNPI FAGLQPSNGF
300
301
YTSKNFLPLV SDGSKPGLCA CKAAAGLPKL HGNVIVLGAG DTAFDCATSA
350
351
LRCGARRVFV VFRKGSSGIR AVPEEVELAR DERCELLPYL SPRKVIVKDG
400
401
LITAMEFCRT EQNENDEWVE DEEQTQRLKA NFVISAFGSG LEDQDVKAAL
450
451
APLQFRGELP VVDRVTMQSS VKQVFLGGDL AGVANTTVES VNDGKVAAWS
500
501
IHCQLQGLPL DTPAALPLFY TDIDAVDISV EMCGIRFENP FGLASAPPTT
550
551
STAMIRRAFE QGWGFVVTKT FGLDKDLVTN VSPRIVRGTT SGYKYGPQQG
600
601
CFLNIELISE KRAEYWLKSI GELKRDFPEK IVIASIMCSF NEEDWTELAI
650
651
KAEQSGADAL ELNLSCPHGM GERGMGLACG QDPELVEQIS RWVRKAVKLP
700
701
FFIKLTPNIT DIVSIAAAAK RGGADGGSAI NTVQGLMGLK ADSTAWPAIG
750
751
KEQRTTYGGV SGNATRPMAL KAISDIANRV PGFPILGIGG IDSGEVALQF
800
801
IHAGATVLQI CSSVQNQDFT VIEDYCTALK ALLYLKANPP PVDGPFWDGQ
850
851
SPPTPVHQKG KPVVRLTGEG KATLGFFGPY QRQRDIKMAE LRSQKGALWD
900
901
AEQVKATPPA SNGAPNPAPR IKDVIGAALD KIGSYNKLDN KQQKVALIDD
950
951
DMCINCGKCY MTCADSGYQA IEFDKDTHIP HVNDDCTGCT LCVSVCPIID
1000
1001
CITMVPKKIP HVIKRGVEEK IFYTHALSQC Q                    
1031
 

Show the unformatted sequence.

Checksums:
CRC64:FD3CF291078E19B8
MD5:4bfa254530aa1c65fba48ca20a0f0c1d

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;