Please note: this site relies heavily on the use of javascript. Without a javascript-enabled browser, this site will not function correctly. Please enable javascript and reload the page, or switch to a different browser.
30  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: CARM1_MOUSE (Q9WVG6)

Summary

This is the summary of UniProt entry CARM1_MOUSE (Q9WVG6).

Description: Histone-arginine methyltransferase CARM1
Source organism: Mus musculus (Mouse) (NCBI taxonomy ID 10090)
Length: 608 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

Show or hide the data used to generate the graphic in JSON format.

Source Domain Start End
low_complexity n/a 2 30
Pfam CARM1 29 140
Pfam PrmA 173 287
low_complexity n/a 477 494
disorder n/a 481 495
disorder n/a 542 543
disorder n/a 555 579
low_complexity n/a 562 576
disorder n/a 605 606

Show or hide domain scores.

Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9WVG6. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MAAAAATAVG PGAGSAGVAG PGGAGPCATV SVFPGARLLT IGDANGEIQR
50
51
HAEQQALRLE VRAGPDAAGI ALYSHEDVCV FKCSVSRETE CSRVGRQSFI
100
101
ITLGCNSVLI QFATPHDFCS FYNILKTCRG HTLERSVFSE RTEESSAVQY
150
151
FQFYGYLSQQ QNMMQDYVRT GTYQRAILQN HTDFKDKIVL DVGCGSGILS
200
201
FFAAQAGARK IYAVEASTMA QHAEVLVKSN NLTDRIVVIP GKVEEVSLPE
250
251
QVDIIISEPM GYMLFNERML ESYLHAKKYL KPSGNMFPTI GDVHLAPFTD
300
301
EQLYMEQFTK ANFWYQPSFH GVDLSALRGA AVDEYFRQPV VDTFDIRILM
350
351
AKSVKYTVNF LEAKEGDLHR IEIPFKFHML HSGLVHGLAF WFDVAFIGSI
400
401
MTVWLSTAPT EPLTHWYQVR CLFQSPLFAK AGDTLSGTCL LIANKRQSYD
450
451
ISIVAQVDQT GSKSSNLLDL KNPFFRYTGT TPSPPPGSHY TSPSENMWNT
500
501
GSTYNLSSGV AVAGMPTAYD LSSVIAGGSS VGHNNLIPLA NTGIVNHTHS
550
551
RMGSIMSTGI VQGSSGAQGG GGSSSAHYAV NNQFTMGGPA ISMASPMSIP
600
601
TNTMHYGS                                              
608
 

Show the unformatted sequence.

Checksums:
CRC64:C621F2AA9FBA2DA3
MD5:c4ee8d10bb4228f118cd186527dcc7ec

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
CARM1 135 - 140 5IH3 B 135 - 140 Show 3D Structure View in InterPro
5IS6 B 135 - 140 Show 3D Structure View in InterPro
D 135 - 140 Show 3D Structure View in InterPro
5ISG B 135 - 140 Show 3D Structure View in InterPro
D 135 - 140 Show 3D Structure View in InterPro
5K8V B 135 - 140 Show 3D Structure View in InterPro
5K8W A 135 - 140 Show 3D Structure View in InterPro
B 135 - 140 Show 3D Structure View in InterPro
5K8X B 135 - 140 Show 3D Structure View in InterPro
D 135 - 140 Show 3D Structure View in InterPro
5LGP B 135 - 140 Show 3D Structure View in InterPro
5LGQ A 135 - 140 Show 3D Structure View in InterPro
B 135 - 140 Show 3D Structure View in InterPro
D 135 - 140 Show 3D Structure View in InterPro
5LGR A 135 - 140 Show 3D Structure View in InterPro
B 135 - 140 Show 3D Structure View in InterPro
C 135 - 140 Show 3D Structure View in InterPro
D 135 - 140 Show 3D Structure View in InterPro
5LGS A 135 - 140 Show 3D Structure View in InterPro
B 135 - 140 Show 3D Structure View in InterPro
D 135 - 140 Show 3D Structure View in InterPro
5LV2 B 135 - 140 Show 3D Structure View in InterPro
F 135 - 140 Show 3D Structure View in InterPro
5LV3 B 135 - 140 Show 3D Structure View in InterPro
D 135 - 140 Show 3D Structure View in InterPro
5TBH B 135 - 140 Show 3D Structure View in InterPro
5TBI B 135 - 140 Show 3D Structure View in InterPro
5TBJ B 135 - 140 Show 3D Structure View in InterPro
D 135 - 140 Show 3D Structure View in InterPro
136 - 140 5IH3 A 136 - 140 Show 3D Structure View in InterPro
C 136 - 140 Show 3D Structure View in InterPro
D 136 - 140 Show 3D Structure View in InterPro
5IS6 A 136 - 140 Show 3D Structure View in InterPro
C 136 - 140 Show 3D Structure View in InterPro
5IS7 A 136 - 140 Show 3D Structure View in InterPro
B 136 - 140 Show 3D Structure View in InterPro
5IS9 A 136 - 140 Show 3D Structure View in InterPro
B 136 - 140 Show 3D Structure View in InterPro
C 136 - 140 Show 3D Structure View in InterPro
D 136 - 140 Show 3D Structure View in InterPro
5ISA A 136 - 140 Show 3D Structure View in InterPro
B 136 - 140 Show 3D Structure View in InterPro
C 136 - 140 Show 3D Structure View in InterPro
D 136 - 140 Show 3D Structure View in InterPro
5ISB A 136 - 140 Show 3D Structure View in InterPro
B 136 - 140 Show 3D Structure View in InterPro
C 136 - 140 Show 3D Structure View in InterPro
D 136 - 140 Show 3D Structure View in InterPro
5ISC B 136 - 140 Show 3D Structure View in InterPro
C 136 - 140 Show 3D Structure View in InterPro
D 136 - 140 Show 3D Structure View in InterPro
5ISD A 136 - 140 Show 3D Structure View in InterPro
C 136 - 140 Show 3D Structure View in InterPro
D 136 - 140 Show 3D Structure View in InterPro
5ISE A 136 - 140 Show 3D Structure View in InterPro
B 136 - 140 Show 3D Structure View in InterPro
C 136 - 140 Show 3D Structure View in InterPro
D 136 - 140 Show 3D Structure View in InterPro
5ISF A 136 - 140 Show 3D Structure View in InterPro
B 136 - 140 Show 3D Structure View in InterPro
C 136 - 140 Show 3D Structure View in InterPro
D 136 - 140 Show 3D Structure View in InterPro
5ISG A 136 - 140 Show 3D Structure View in InterPro
C 136 - 140 Show 3D Structure View in InterPro
5ISH A 136 - 140 Show 3D Structure View in InterPro
B 136 - 140 Show 3D Structure View in InterPro
C 136 - 140 Show 3D Structure View in InterPro
D 136 - 140 Show 3D Structure View in InterPro
5ISI A 136 - 140 Show 3D Structure View in InterPro
B 136 - 140 Show 3D Structure View in InterPro
C 136 - 140 Show 3D Structure View in InterPro
D 136 - 140 Show 3D Structure View in InterPro
5K8V A 136 - 140 Show 3D Structure View in InterPro
C 136 - 140 Show 3D Structure View in InterPro
D 136 - 140 Show 3D Structure View in InterPro
5K8W C 136 - 140 Show 3D Structure View in InterPro
D 136 - 140 Show 3D Structure View in InterPro
5K8X A 136 - 140 Show 3D Structure View in InterPro
C 136 - 140 Show 3D Structure View in InterPro
5LGP A 136 - 140 Show 3D Structure View in InterPro
C 136 - 140 Show 3D Structure View in InterPro
D 136 - 140 Show 3D Structure View in InterPro
5LGQ C 136 - 140 Show 3D Structure View in InterPro
5LGS C 136 - 140 Show 3D Structure View in InterPro
5LKJ A 136 - 140 Show 3D Structure View in InterPro
B 136 - 140 Show 3D Structure View in InterPro
C 136 - 140 Show 3D Structure View in InterPro
D 136 - 140 Show 3D Structure View in InterPro
5LV2 A 136 - 140 Show 3D Structure View in InterPro
C 136 - 140 Show 3D Structure View in InterPro
D 136 - 140 Show 3D Structure View in InterPro
E 136 - 140 Show 3D Structure View in InterPro
G 136 - 140 Show 3D Structure View in InterPro
H 136 - 140 Show 3D Structure View in InterPro
5LV3 A 136 - 140 Show 3D Structure View in InterPro
C 136 - 140 Show 3D Structure View in InterPro
5TBH A 136 - 140 Show 3D Structure View in InterPro
C 136 - 140 Show 3D Structure View in InterPro
D 136 - 140 Show 3D Structure View in InterPro
5TBI A 136 - 140 Show 3D Structure View in InterPro
C 136 - 140 Show 3D Structure View in InterPro
D 136 - 140 Show 3D Structure View in InterPro
5TBJ A 136 - 140 Show 3D Structure View in InterPro
C 136 - 140 Show 3D Structure View in InterPro
137 - 140 5IS7 C 137 - 140 Show 3D Structure View in InterPro
D 137 - 140 Show 3D Structure View in InterPro
5ISC A 137 - 140 Show 3D Structure View in InterPro
PrmA 173 - 287 2V74 B 173 - 287 Show 3D Structure View in InterPro
D 173 - 287 Show 3D Structure View in InterPro
F 173 - 287 Show 3D Structure View in InterPro
H 173 - 287 Show 3D Structure View in InterPro
2V7E A 173 - 287 Show 3D Structure View in InterPro
B 173 - 287 Show 3D Structure View in InterPro
5IH3 A 173 - 287 Show 3D Structure View in InterPro
B 173 - 287 Show 3D Structure View in InterPro
C 173 - 287 Show 3D Structure View in InterPro
D 173 - 287 Show 3D Structure View in InterPro
5IS6 A 173 - 287 Show 3D Structure View in InterPro
B 173 - 287 Show 3D Structure View in InterPro
C 173 - 287 Show 3D Structure View in InterPro
D 173 - 287 Show 3D Structure View in InterPro
5IS7 A 173 - 287 Show 3D Structure View in InterPro
B 173 - 287 Show 3D Structure View in InterPro
C 173 - 287 Show 3D Structure View in InterPro
D 173 - 287 Show 3D Structure View in InterPro
5IS8 A 173 - 287 Show 3D Structure View in InterPro
B 173 - 287 Show 3D Structure View in InterPro
C 173 - 287 Show 3D Structure View in InterPro
D 173 - 287 Show 3D Structure View in InterPro
5IS9 A 173 - 287 Show 3D Structure View in InterPro
B 173 - 287 Show 3D Structure View in InterPro
C 173 - 287 Show 3D Structure View in InterPro
D 173 - 287 Show 3D Structure View in InterPro
5ISA A 173 - 287 Show 3D Structure View in InterPro
B 173 - 287 Show 3D Structure View in InterPro
C 173 - 287 Show 3D Structure View in InterPro
D 173 - 287 Show 3D Structure View in InterPro
5ISB A 173 - 287 Show 3D Structure View in InterPro
B 173 - 287 Show 3D Structure View in InterPro
C 173 - 287 Show 3D Structure View in InterPro
D 173 - 287 Show 3D Structure View in InterPro
5ISC A 173 - 287 Show 3D Structure View in InterPro
B 173 - 287 Show 3D Structure View in InterPro
C 173 - 287 Show 3D Structure View in InterPro
D 173 - 287 Show 3D Structure View in InterPro
5ISD A 173 - 287 Show 3D Structure View in InterPro
B 173 - 287 Show 3D Structure View in InterPro
C 173 - 287 Show 3D Structure View in InterPro
D 173 - 287 Show 3D Structure View in InterPro
5ISE A 173 - 287 Show 3D Structure View in InterPro
B 173 - 287 Show 3D Structure View in InterPro
C 173 - 287 Show 3D Structure View in InterPro
D 173 - 287 Show 3D Structure View in InterPro
5ISF A 173 - 287 Show 3D Structure View in InterPro
B 173 - 287 Show 3D Structure View in InterPro
C 173 - 287 Show 3D Structure View in InterPro
D 173 - 287 Show 3D Structure View in InterPro
5ISG A 173 - 287 Show 3D Structure View in InterPro
B 173 - 287 Show 3D Structure View in InterPro
C 173 - 287 Show 3D Structure View in InterPro
D 173 - 287 Show 3D Structure View in InterPro
5ISH A 173 - 287 Show 3D Structure View in InterPro
B 173 - 287 Show 3D Structure View in InterPro
C 173 - 287 Show 3D Structure View in InterPro
D 173 - 287 Show 3D Structure View in InterPro
5ISI A 173 - 287 Show 3D Structure View in InterPro
B 173 - 287 Show 3D Structure View in InterPro
C 173 - 287 Show 3D Structure View in InterPro
D 173 - 287 Show 3D Structure View in InterPro
5K8V A 173 - 287 Show 3D Structure View in InterPro
B 173 - 287 Show 3D Structure View in InterPro
C 173 - 287 Show 3D Structure View in InterPro
D 173 - 287 Show 3D Structure View in InterPro
5K8W A 173 - 287 Show 3D Structure View in InterPro
B 173 - 287 Show 3D Structure View in InterPro
C 173 - 287 Show 3D Structure View in InterPro
D 173 - 287 Show 3D Structure View in InterPro
5K8X A 173 - 287 Show 3D Structure View in InterPro
B 173 - 287 Show 3D Structure View in InterPro
C 173 - 287 Show 3D Structure View in InterPro
D 173 - 287 Show 3D Structure View in InterPro
5LGP A 173 - 287 Show 3D Structure View in InterPro
B 173 - 287 Show 3D Structure View in InterPro
C 173 - 287 Show 3D Structure View in InterPro
D 173 - 287 Show 3D Structure View in InterPro
5LGQ A 173 - 287 Show 3D Structure View in InterPro
B 173 - 287 Show 3D Structure View in InterPro
C 173 - 287 Show 3D Structure View in InterPro
D 173 - 287 Show 3D Structure View in InterPro
5LGR A 173 - 287 Show 3D Structure View in InterPro
B 173 - 287 Show 3D Structure View in InterPro
C 173 - 287 Show 3D Structure View in InterPro
D 173 - 287 Show 3D Structure View in InterPro
5LGS A 173 - 287 Show 3D Structure View in InterPro
B 173 - 287 Show 3D Structure View in InterPro
C 173 - 287 Show 3D Structure View in InterPro
D 173 - 287 Show 3D Structure View in InterPro
5LKJ A 173 - 287 Show 3D Structure View in InterPro
B 173 - 287 Show 3D Structure View in InterPro
C 173 - 287 Show 3D Structure View in InterPro
D 173 - 287 Show 3D Structure View in InterPro
5LV2 A 173 - 287 Show 3D Structure View in InterPro
B 173 - 287 Show 3D Structure View in InterPro
C 173 - 287 Show 3D Structure View in InterPro
D 173 - 287 Show 3D Structure View in InterPro
E 173 - 287 Show 3D Structure View in InterPro
F 173 - 287 Show 3D Structure View in InterPro
G 173 - 287 Show 3D Structure View in InterPro
H 173 - 287 Show 3D Structure View in InterPro
5LV3 A 173 - 287 Show 3D Structure View in InterPro
B 173 - 287 Show 3D Structure View in InterPro
C 173 - 287 Show 3D Structure View in InterPro
D 173 - 287 Show 3D Structure View in InterPro
5NTC A 173 - 287 Show 3D Structure View in InterPro
B 173 - 287 Show 3D Structure View in InterPro
C 173 - 287 Show 3D Structure View in InterPro
D 173 - 287 Show 3D Structure View in InterPro
5TBH A 173 - 287 Show 3D Structure View in InterPro
B 173 - 287 Show 3D Structure View in InterPro
C 173 - 287 Show 3D Structure View in InterPro
D 173 - 287 Show 3D Structure View in InterPro
5TBI A 173 - 287 Show 3D Structure View in InterPro
B 173 - 287 Show 3D Structure View in InterPro
C 173 - 287 Show 3D Structure View in InterPro
D 173 - 287 Show 3D Structure View in InterPro
5TBJ A 173 - 287 Show 3D Structure View in InterPro
B 173 - 287 Show 3D Structure View in InterPro
C 173 - 287 Show 3D Structure View in InterPro
D 173 - 287 Show 3D Structure View in InterPro
×

The parts of the structure corresponding to the Pfam family are highlighted in blue.

Loading Structure Data

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;