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1  structure 1  species 0  interactions 1  sequence 1  architecture

Protein: PTH2_HUMAN (Q9Y3E5)

Summary

This is the summary of UniProt entry PTH2_HUMAN (Q9Y3E5).

Description: Peptidyl-tRNA hydrolase 2, mitochondrial EC=3.1.1.29
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 179 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

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Source Domain Start End
transmembrane n/a 16 37
disorder n/a 47 56
Pfam PTH2 65 179

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9Y3E5. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MPSKSLVMEY LAHPSTLGLA VGVACGMCLG WSLRVCFGML PKSKTSKTHT
50
51
DTESEASILG DSGEYKMILV VRNDLKMGKG KVAAQCSHAA VSAYKQIQRR
100
101
NPEMLKQWEY CGQPKVVVKA PDEETLIALL AHAKMLGLTV SLIQDAGRTQ
150
151
IAPGSQTVLG IGPGPADLID KVTGHLKLY                       
179
 

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Checksums:
CRC64:11A0BA9ECF6B5E46
MD5:7c38494fff9efd80bd6c9eaa8204e584

Structures

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from the PDBe SIFTS project, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the mapping between Pfam domains, this UniProt entry and a corresponding three dimensional structure.

Pfam family UniProt residues PDB ID PDB chain ID PDB residues View
PTH2 65 - 179 1Q7S A 65 - 179 NGL View in InterPro
B 65 - 179 NGL View in InterPro
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TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.