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0  structures 1  species 0  interactions 1  sequence 1  architecture

Protein: SCNAA_HUMAN (Q9Y5Y9)

Summary

This is the summary of UniProt entry SCNAA_HUMAN (Q9Y5Y9).

Description: Sodium channel protein type 10 subunit alpha
Source organism: Homo sapiens (Human) (NCBI taxonomy ID 9606)
Length: 1956 amino acids
Reference Proteome: ✓

Please note: when we start each new Pfam data release, we take a copy of the UniProt sequence database. This snapshot of UniProt forms the basis of the overview that you see here. It is important to note that, although some UniProt entries may be removed after a Pfam release, these entries will not be removed from Pfam until the next Pfam data release.

Pfam domains

Download the data used to generate the domain graphic in JSON format.

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Source Domain Start End
disorder n/a 27 28
disorder n/a 32 54
transmembrane n/a 128 146
Pfam Ion_trans 129 408
transmembrane n/a 158 177
transmembrane n/a 189 210
transmembrane n/a 222 243
transmembrane n/a 249 268
transmembrane n/a 372 400
coiled_coil n/a 397 431
disorder n/a 408 413
disorder n/a 443 495
disorder n/a 500 583
low_complexity n/a 535 550
transmembrane n/a 657 683
Pfam Ion_trans 664 899
transmembrane n/a 695 717
transmembrane n/a 729 747
low_complexity n/a 751 764
transmembrane n/a 784 804
transmembrane n/a 835 855
transmembrane n/a 867 890
low_complexity n/a 871 884
low_complexity n/a 879 895
Pfam Na_trans_assoc 904 1147
disorder n/a 949 950
disorder n/a 960 994
disorder n/a 999 1089
low_complexity n/a 1001 1016
disorder n/a 1102 1103
low_complexity n/a 1102 1113
Pfam Ion_trans 1151 1429
transmembrane n/a 1153 1171
transmembrane n/a 1192 1208
transmembrane n/a 1220 1238
low_complexity n/a 1248 1263
transmembrane n/a 1269 1295
transmembrane n/a 1394 1418
low_complexity n/a 1398 1408
transmembrane n/a 1468 1491
Pfam Ion_trans 1475 1733
transmembrane n/a 1511 1529
transmembrane n/a 1541 1560
transmembrane n/a 1566 1584
low_complexity n/a 1573 1590
transmembrane n/a 1596 1624
disorder n/a 1682 1685
transmembrane n/a 1699 1722
low_complexity n/a 1699 1712
disorder n/a 1877 1885
disorder n/a 1890 1891
disorder n/a 1908 1912
disorder n/a 1914 1956

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Sequence information

This is the amino acid sequence of the UniProt sequence database entry with the accession Q9Y5Y9. This sequence is stored in the Pfam database and updated with each new Pfam release, but this means that the sequence we store may differ from that stored by UniProt.

Sequence:
1
MEFPIGSLET NNFRRFTPES LVEIEKQIAA KQGTKKAREK HREQKDQEEK
50
51
PRPQLDLKAC NQLPKFYGEL PAELIGEPLE DLDPFYSTHR TFMVLNKGRT
100
101
ISRFSATRAL WLFSPFNLIR RTAIKVSVHS WFSLFITVTI LVNCVCMTRT
150
151
DLPEKIEYVF TVIYTFEALI KILARGFCLN EFTYLRDPWN WLDFSVITLA
200
201
YVGTAIDLRG ISGLRTFRVL RALKTVSVIP GLKVIVGALI HSVKKLADVT
250
251
ILTIFCLSVF ALVGLQLFKG NLKNKCVKND MAVNETTNYS SHRKPDIYIN
300
301
KRGTSDPLLC GNGSDSGHCP DGYICLKTSD NPDFNYTSFD SFAWAFLSLF
350
351
RLMTQDSWER LYQQTLRTSG KIYMIFFVLV IFLGSFYLVN LILAVVTMAY
400
401
EEQNQATTDE IEAKEKKFQE ALEMLRKEQE VLAALGIDTT SLHSHNGSPL
450
451
TSKNASERRH RIKPRVSEGS TEDNKSPRSD PYNQRRMSFL GLASGKRRAS
500
501
HGSVFHFRSP GRDISLPEGV TDDGVFPGDH ESHRGSLLLG GGAGQQGPLP
550
551
RSPLPQPSNP DSRHGEDEHQ PPPTSELAPG AVDVSAFDAG QKKTFLSAEY
600
601
LDEPFRAQRA MSVVSIITSV LEELEESEQK CPPCLTSLSQ KYLIWDCCPM
650
651
WVKLKTILFG LVTDPFAELT ITLCIVVNTI FMAMEHHGMS PTFEAMLQIG
700
701
NIVFTIFFTA EMVFKIIAFD PYYYFQKKWN IFDCIIVTVS LLELGVAKKG
750
751
SLSVLRSFRL LRVFKLAKSW PTLNTLIKII GNSVGALGNL TIILAIIVFV
800
801
FALVGKQLLG ENYRNNRKNI SAPHEDWPRW HMHDFFHSFL IVFRILCGEW
850
851
IENMWACMEV GQKSICLILF LTVMVLGNLV VLNLFIALLL NSFSADNLTA
900
901
PEDDGEVNNL QVALARIQVF GHRTKQALCS FFSRSCPFPQ PKAEPELVVK
950
951
LPLSSSKAEN HIAANTARGS SGGLQAPRGP RDEHSDFIAN PTVWVSVPIA
1000
1001
EGESDLDDLE DDGGEDAQSF QQEVIPKGQQ EQLQQVERCG DHLTPRSPGT
1050
1051
GTSSEDLAPS LGETWKDESV PQVPAEGVDD TSSSEGSTVD CLDPEEILRK
1100
1101
IPELADDLEE PDDCFTEGCI RHCPCCKLDT TKSPWDVGWQ VRKTCYRIVE
1150
1151
HSWFESFIIF MILLSSGSLA FEDYYLDQKP TVKALLEYTD RVFTFIFVFE
1200
1201
MLLKWVAYGF KKYFTNAWCW LDFLIVNISL ISLTAKILEY SEVAPIKALR
1250
1251
TLRALRPLRA LSRFEGMRVV VDALVGAIPS IMNVLLVCLI FWLIFSIMGV
1300
1301
NLFAGKFWRC INYTDGEFSL VPLSIVNNKS DCKIQNSTGS FFWVNVKVNF
1350
1351
DNVAMGYLAL LQVATFKGWM DIMYAAVDSR EVNMQPKWED NVYMYLYFVI
1400
1401
FIIFGGFFTL NLFVGVIIDN FNQQKKKLGG QDIFMTEEQK KYYNAMKKLG
1450
1451
SKKPQKPIPR PLNKFQGFVF DIVTRQAFDI TIMVLICLNM ITMMVETDDQ
1500
1501
SEEKTKILGK INQFFVAVFT GECVMKMFAL RQYYFTNGWN VFDFIVVVLS
1550
1551
IASLIFSAIL KSLQSYFSPT LFRVIRLARI GRILRLIRAA KGIRTLLFAL
1600
1601
MMSLPALFNI GLLLFLVMFI YSIFGMSSFP HVRWEAGIDD MFNFQTFANS
1650
1651
MLCLFQITTS AGWDGLLSPI LNTGPPYCDP NLPNSNGTRG DCGSPAVGII
1700
1701
FFTTYIIISF LIMVNMYIAV ILENFNVATE ESTEPLSEDD FDMFYETWEK
1750
1751
FDPEATQFIT FSALSDFADT LSGPLRIPKP NRNILIQMDL PLVPGDKIHC
1800
1801
LDILFAFTKN VLGESGELDS LKANMEEKFM ATNLSKSSYE PIATTLRWKQ
1850
1851
EDISATVIQK AYRSYVLHRS MALSNTPCVP RAEEEAASLP DEGFVAFTAN
1900
1901
ENCVLPDKSE TASATSFPPS YESVTRGLSD RVNMRTSSSI QNEDEATSME
1950
1951
LIAPGP                                                
1956
 

Show the unformatted sequence.

Checksums:
CRC64:4A4A2C5E135B6685
MD5:b6666f74fe7b2a81880e169fe6f7fd7f

TreeFam

Below is a phylogenetic tree of animal genes, with ortholog and paralog assignments, from TreeFam.

AlphaFold Structure Prediction

The protein structure below has been predicted by DeepMind with AlphaFold. For more information, please visit the AlphaFold page for this protein.

Model confidence scale

  Very High (pLDDT > 90)
  Confident (90 > pLDDT > 70)
  Low (70 > pLDDT > 50)
  Very Low (pLDDT < 50)
Highly accurate protein structure prediction with AlphaFold. John Jumper, Richard Evans, Alexander Pritzel, Tim Green, Michael Figurnov, Olaf Ronneberger, Kathryn Tunyasuvunakool, Russ Bates, Augustin Žídek, Anna Potapenko, Alex Bridgland, Clemens Meyer, Simon A. A. Kohl, Andrew J. Ballard, Andrew Cowie, Bernardino Romera-Paredes, Stanislav Nikolov, Rishub Jain, Jonas Adler, Trevor Back, Stig Petersen, David Reiman, Ellen Clancy, Michal Zielinski, Martin Steinegger, Michalina Pacholska, Tamas Berghammer, Sebastian Bodenstein, David Silver, Oriol Vinyals, Andrew W. Senior, Koray Kavukcuoglu, Pushmeet Kohli & Demis Hassabis Nature 2021-07-15; DOI: 10.1038/s41586-021-03819-2;