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Structure: 5FUC

Summary

5fuc
PDB entry 5fuc: Biophysical and cellular characterisation of a junctional epitope antibody that locks IL-6 and gp80 together in a stable complex: implications for new therapeutic strategies
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PDB entry 5fuc

Biophysical and cellular characterisation of a junctional epitope antibody that locks il-6 and gp80 together in a stable complex: implications for new therapeutic strategies

Experiment type: X-ray diffraction, resolution 2.70Å
Release date: 2020-07-29
Authors: Adams, R., Griffin, R., Doyle, C., Ettorre, A.
Species: Homo sapiens (Human)

PDBprint

Below is the PDBprint for entry 5fuc.

External database links

Domain organisation

Many structures in the PDB are linked to one or more UniProt protein sequence entries. This section shows the Pfam domains which are found on the UniProt sequence(s) referred to by this structure.

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Sequence mapping

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from PDBe, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the sequences and Pfam domains that correspond to this structure.

PDB UniProt Pfam family
Chain Start End ID Start End
A 21 184 P05231 49 212 IL6 (PF00489)
B 21 184 P05231 49 212 IL6 (PF00489)
C 99 194 P08887 118 213 IL6Ra-bind (PF09240)
D 99 194 P08887 118 213 IL6Ra-bind (PF09240)

Note: This mapping was provided by the PDBe group.

View structure

View Pfam families and other data mapped to the structure of PDB entry 5fuc in InterPro