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Structure: 5Q04

Summary

5q04
PDB entry 5q04: Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, E.C.3.1.3.11) complexed with the allosteric inhibitor 1-(4-bromo-5-chlorothiophen-2-yl)sulfonyl-3-(5-bromo-1,3-thiazol-2-yl)urea
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PDB entry 5q04

Human liver fructose-1,6-bisphosphatase 1 (fructose 1,6-bisphosphate 1-phosphatase, e.c.3.1.3.11) complexed with the allosteric inhibitor 1-(4-bromo-5-chlorothiophen-2-yl)sulfonyl-3-(5-bromo-1,3-thiazol-2-yl)urea

Experiment type: X-ray diffraction, resolution 2.50Å
Release date: 2019-02-06
Authors: Ruf, A., Joseph, C., Alker, A., Banner, D., Tetaz, T., Benz, J., Kuhn, B., Rudolph, M.G., Yang, H., Shao, C., Burley, S.K.
Species: Homo sapiens (Human)

PDBprint

Below is the PDBprint for entry 5q04.

External database links

Domain organisation

Many structures in the PDB are linked to one or more UniProt protein sequence entries. This section shows the Pfam domains which are found on the UniProt sequence(s) referred to by this structure.

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Sequence mapping

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from PDBe, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the sequences and Pfam domains that correspond to this structure.

PDB UniProt Pfam family
Chain Start End ID Start End
A 11 198 P09467 12 199 FBPase (PF00316)
A 202 332 P09467 203 333 FBPase_C (PF18913)
B 11 198 P09467 12 199 FBPase (PF00316)
B 202 332 P09467 203 333 FBPase_C (PF18913)
C 11 198 P09467 12 199 FBPase (PF00316)
C 202 332 P09467 203 333 FBPase_C (PF18913)
D 11 198 P09467 12 199 FBPase (PF00316)
D 202 332 P09467 203 333 FBPase_C (PF18913)
E 11 198 P09467 12 199 FBPase (PF00316)
E 202 332 P09467 203 333 FBPase_C (PF18913)
F 11 198 P09467 12 199 FBPase (PF00316)
F 202 332 P09467 203 333 FBPase_C (PF18913)
G 11 198 P09467 12 199 FBPase (PF00316)
G 202 332 P09467 203 333 FBPase_C (PF18913)
H 11 198 P09467 12 199 FBPase (PF00316)
H 202 332 P09467 203 333 FBPase_C (PF18913)

Note: This mapping was provided by the PDBe group.

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View Pfam families and other data mapped to the structure of PDB entry 5q04 in InterPro