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1  structure 1  species 0  interactions 52  sequences 38  architectures

Structure: 6AH0

Summary

6ah0
PDB entry 6ah0: The Cryo-EM Structure of the Precusor of Human Pre-catalytic Spliceosome (pre-B complex)
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PDB entry 6ah0

The cryo-em structure of the precusor of human pre-catalytic spliceosome (pre-b complex)

Experiment type: Electron Microscopy, resolution 5.70Å
Release date: 2020-10-14
Authors: Zhan, X., Yan, C., Zhang, X., Shi, Y.
Species: Homo sapiens (Human)

PDBprint

Below is the PDBprint for entry 6ah0.

External database links

Domain organisation

Many structures in the PDB are linked to one or more UniProt protein sequence entries. This section shows the Pfam domains which are found on the UniProt sequence(s) referred to by this structure.

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Sequence mapping

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from PDBe, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the sequences and Pfam domains that correspond to this structure.

PDB UniProt Pfam family
Chain Start End ID Start End
1 394 447 O75533 394 447 SF3b1 (PF08920)
2 470 596 Q13435 470 596 DUF382 (PF04037)
2 605 655 Q13435 605 655 PSP (PF04046)
3 76 592 Q15393 76 592 MMS1_N (PF10433)
3 863 1184 Q15393 863 1184 CPSF_A (PF03178)
4 15 85 Q15427 15 85 RRM_1 (PF00076)
5 21 88 Q9Y3B4 21 88 RRM_1 (PF00076)
6 7 95 Q7RTV0 7 95 PHF5 (PF03660)
7 15 80 Q9BWJ5 15 80 SF3b10 (PF07189)
a 33 111 P62316 33 111 LSM (PF01423)
A 58 209 Q6P2Q9 58 209 PRO8NT (PF08082)
A 395 801 Q6P2Q9 395 801 PROCN (PF08083)
A 986 1077 Q6P2Q9 986 1077 RRM_4 (PF10598)
A 1210 1343 Q6P2Q9 1210 1343 U5_2-snRNA_bdg (PF10597)
A 1442 1600 Q6P2Q9 1442 1600 U6-snRNA_bdg (PF10596)
A 1760 1989 Q6P2Q9 1760 1989 PRP8_domainIV (PF12134)
A 2099 2205 Q6P2Q9 2099 2205 JAB (PF01398)
A 2212 2333 Q6P2Q9 2212 2333 PROCT (PF08084)
b 9 74 P62306 9 74 LSM (PF01423)
c 23 89 P62304 23 89 LSM (PF01423)
C 127 440 Q15029 127 440 GTP_EFTU (PF00009)
C 489 566 Q15029 489 566 GTP_EFTU_D2 (PF03144)
C 584 656 Q15029 584 656 EFG_III (PF14492)
C 703 824 Q15029 703 824 EFG_IV (PF03764)
C 826 915 Q15029 826 915 EFG_C (PF00679)
d 7 72 P62308 7 72 LSM (PF01423)
D 264 363 O75643 264 363 Helicase_PWI (PF18149)
D 482 663 O75643 482 663 DEAD (PF00270)
D 703 860 O75643 703 860 Helicase_C (PF00271)
D 981 1285 O75643 981 1285 Sec63 (PF02889)
D 1329 1514 O75643 1329 1514 DEAD (PF00270)
D 1812 2123 O75643 1812 2123 Sec63 (PF02889)
e 8 73 P62318 8 73 LSM (PF01423)
E 58 94 Q96DI7 58 94 WD40 (PF00400)
E 99 137 Q96DI7 99 137 WD40 (PF00400)
E 141 180 Q96DI7 141 180 WD40 (PF00400)
E 186 221 Q96DI7 186 221 WD40 (PF00400)
E 224 263 Q96DI7 224 263 WD40 (PF00400)
E 271 313 Q96DI7 271 313 WD40 (PF00400)
E 317 353 Q96DI7 317 353 WD40 (PF00400)
f 7 82 P14678 7 82 LSM (PF01423)
g 5 70 P62314 5 70 LSM (PF01423)
h 8 73 P62318 8 73 LSM (PF01423)
i 7 82 P14678 7 82 LSM (PF01423)
j 5 70 P62314 5 70 LSM (PF01423)
J 436 472 O43395 436 472 PRP3 (PF08572)
J 544 672 O43395 544 672 DUF1115 (PF06544)
k 33 111 P62316 33 111 LSM (PF01423)
K 215 259 O43172 215 259 WD40 (PF00400)
K 263 309 O43172 263 309 WD40 (PF00400)
K 316 351 O43172 316 351 WD40 (PF00400)
K 397 435 O43172 397 435 WD40 (PF00400)
K 439 478 O43172 439 478 WD40 (PF00400)
K 482 520 O43172 482 520 WD40 (PF00400)
l 23 89 P62304 23 89 LSM (PF01423)
L 99 330 Q8WWY3 99 330 Nop (PF01798)
m 9 74 P62306 9 74 LSM (PF01423)
M 20 114 P55769 20 114 Ribosomal_L7Ae (PF01248)
n 7 72 P62308 7 72 LSM (PF01423)
N 13 167 O94906 13 167 PRP1_N (PF06424)
N 710 740 O94906 710 740 TPR_8 (PF13181)
o 2 163 P09661 2 163 LRR_9 (PF14580)
O 4 136 P83876 4 136 DIM1 (PF02966)
p 9 80 P08579 9 80 RRM_1 (PF00076)
P 33 111 P62316 33 111 LSM (PF01423)
q 5 72 Q9Y333 5 72 LSM (PF01423)
Q 9 74 P62306 9 74 LSM (PF01423)
r 19 97 P62310 19 97 LSM (PF01423)
R 23 89 P62304 23 89 LSM (PF01423)
s 5 71 Q9Y4Z0 5 71 LSM (PF01423)
S 7 72 P62308 7 72 LSM (PF01423)
T 8 73 P62318 8 73 LSM (PF01423)
t 16 84 Q9Y4Y9 16 84 LSM (PF01423)
U 7 82 P14678 7 82 LSM (PF01423)
u 164 215 Q15459 164 215 Surp (PF01805)
u 240 302 Q15459 240 302 PRP21_like_P (PF12230)
V 5 70 P62314 5 70 LSM (PF01423)
v 112 206 Q15428 112 206 SF3A2 (PF16835)
w 74 98 Q12874 74 98 SF3a60_bindingd (PF12108)
W 123 186 Q53GS9 123 186 zf-UBP (PF02148)
w 129 180 Q12874 129 180 SF3A3 (PF16837)
w 224 303 Q12874 224 303 SDE2_2C (PF13297)
W 225 552 Q53GS9 225 552 UCH (PF00443)
w 392 499 Q12874 392 499 SF3a60_Prp9_C (PF11931)
x 10 75 P62312 10 75 LSM (PF01423)
X 415 616 Q9BUQ8 415 616 DEAD (PF00270)
X 650 759 Q9BUQ8 650 759 Helicase_C (PF00271)
y 13 86 Q9UK45 13 86 LSM (PF01423)
z 4 72 O95777 4 72 LSM (PF01423)

Note: This mapping was provided by the PDBe group.

View structure

View Pfam families and other data mapped to the structure of PDB entry 6ah0 in InterPro