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1  structure 1  species 0  interactions 57  sequences 46  architectures

Structure: 6FF7

Summary

6ff7
PDB entry 6ff7: human Bact spliceosome core structure
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PDB entry 6ff7

Human bact spliceosome core structure

Experiment type: Electron Microscopy, resolution 4.50Å
Release date: 2020-10-07
Authors: Haselbach, D., Komarov, I., Agafonov, D., Hartmuth, K., Graf, B., Kastner, B., Luehrmann, R., Stark, H.
Species: Homo sapiens (Human)

PDBprint

Below is the PDBprint for entry 6ff7.

External database links

Domain organisation

Many structures in the PDB are linked to one or more UniProt protein sequence entries. This section shows the Pfam domains which are found on the UniProt sequence(s) referred to by this structure.

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Sequence mapping

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from PDBe, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the sequences and Pfam domains that correspond to this structure.

PDB UniProt Pfam family
Chain Start End ID Start End
n/a 281 361 Q8TAD8 281 361 FHA (PF00498)
1 38 108 Q9Y388 38 108 RRM_1 (PF00076)
3 500 602 Q9BRD0 500 602 Bud13 (PF09736)
7 54 78 Q15428 54 78 zf-met (PF12874)
8 470 596 Q13435 470 596 DUF382 (PF04037)
9 74 100 Q12874 74 100 SF3a60_bindingd (PF12108)
9 129 180 Q12874 129 180 SF3A3 (PF16837)
9 224 303 Q12874 224 303 SDE2_2C (PF13297)
9 392 499 Q12874 392 499 SF3a60_Prp9_C (PF11931)
a 33 111 P62316 33 111 LSM (PF01423)
A 58 209 Q6P2Q9 58 209 PRO8NT (PF08082)
A 395 801 Q6P2Q9 395 801 PROCN (PF08083)
A 986 1077 Q6P2Q9 986 1077 RRM_4 (PF10598)
A 1210 1343 Q6P2Q9 1210 1343 U5_2-snRNA_bdg (PF10597)
A 1442 1600 Q6P2Q9 1442 1600 U6-snRNA_bdg (PF10596)
A 1760 1989 Q6P2Q9 1760 1989 PRP8_domainIV (PF12134)
A 2099 2205 Q6P2Q9 2099 2205 JAB (PF01398)
A 2212 2316 Q6P2Q9 2212 2316 PROCT (PF08084)
b 9 74 P62306 9 74 LSM (PF01423)
B 56 110 Q15029 56 110 EFTUD2 (PF16004)
B 127 440 Q15029 127 440 GTP_EFTU (PF00009)
B 489 566 Q15029 489 566 GTP_EFTU_D2 (PF03144)
B 584 656 Q15029 584 656 EFG_III (PF14492)
B 703 824 Q15029 703 824 EFG_IV (PF03764)
B 826 915 Q15029 826 915 EFG_C (PF00679)
c 23 89 P62304 23 89 LSM (PF01423)
C 175 334 Q13573 175 334 SKIP_SNW (PF02731)
d 7 72 P62308 7 72 LSM (PF01423)
D 194 232 O43660 194 232 WD40 (PF00400)
D 236 274 O43660 236 274 WD40 (PF00400)
D 278 316 O43660 278 316 WD40 (PF00400)
D 320 358 O43660 320 358 WD40 (PF00400)
D 403 440 O43660 403 440 WD40 (PF00400)
e 8 73 P62318 8 73 LSM (PF01423)
f 7 82 P14678 7 82 LSM (PF01423)
F 58 94 Q96DI7 58 94 WD40 (PF00400)
F 99 137 Q96DI7 99 137 WD40 (PF00400)
F 141 180 Q96DI7 141 180 WD40 (PF00400)
F 186 221 Q96DI7 186 221 WD40 (PF00400)
F 224 263 Q96DI7 224 263 WD40 (PF00400)
F 271 313 Q96DI7 271 313 WD40 (PF00400)
F 317 353 Q96DI7 317 353 WD40 (PF00400)
G 3 57 Q9UMS4 3 57 U-box (PF04564)
g 5 70 P62314 5 70 LSM (PF01423)
G 67 134 Q9UMS4 67 134 Prp19 (PF08606)
H 3 57 Q9UMS4 3 57 U-box (PF04564)
h 33 111 P62316 33 111 LSM (PF01423)
H 67 134 Q9UMS4 67 134 Prp19 (PF08606)
I 3 57 Q9UMS4 3 57 U-box (PF04564)
i 9 74 P62306 9 74 LSM (PF01423)
I 67 134 Q9UMS4 67 134 Prp19 (PF08606)
J 3 57 Q9UMS4 3 57 U-box (PF04564)
j 23 89 P62304 23 89 LSM (PF01423)
J 67 134 Q9UMS4 67 134 Prp19 (PF08606)
k 7 72 P62308 7 72 LSM (PF01423)
K 13 216 O75934 13 216 BCAS2 (PF05700)
l 8 73 P62318 8 73 LSM (PF01423)
L 11 71 Q99459 11 71 Myb_DNA-bind_6 (PF13921)
L 63 110 Q99459 63 110 Myb_DNA-bind_6 (PF13921)
m 7 82 P14678 7 82 LSM (PF01423)
M 256 285 Q9HCS7 256 285 TPR_8 (PF13181)
M 395 428 Q9HCS7 395 428 TPR_8 (PF13181)
n 5 70 P62314 5 70 LSM (PF01423)
N 21 88 Q9Y3B4 21 88 RRM_1 (PF00076)
o 8 78 Q9UNP9 8 78 RRM_1 (PF00076)
o 143 299 Q9UNP9 143 299 Pro_isomerase (PF00160)
O 256 288 Q9BZJ0 256 288 HAT (PF02184)
O 357 388 Q9BZJ0 357 388 HAT (PF02184)
p 50 101 Q15459 50 101 Surp (PF01805)
p 164 215 Q15459 164 215 Surp (PF01805)
p 232 272 Q15459 232 272 PRP21_like_P (PF12230)
P 234 299 Q9NW64 234 299 RRM_1 (PF00076)
Q 3 140 P41223 3 140 G10 (PF01125)
q 403 563 O60231 402 562 DEAD (PF00270)
q 592 731 O60231 591 730 Helicase_C (PF00271)
q 793 936 O60231 792 935 HA2 (PF04408)
q 940 1016 O60231 939 1015 OB_NTP_bind (PF07717)
R 18 229 Q9P013 18 229 Cwf_Cwc_15 (PF04889)
r 482 663 O75643 482 663 DEAD (PF00270)
r 703 860 O75643 703 860 Helicase_C (PF00271)
r 981 1285 O75643 981 1285 Sec63 (PF02889)
r 1329 1514 O75643 1329 1514 DEAD (PF00270)
r 1812 2123 O75643 1812 2123 Sec63 (PF02889)
s 14 166 Q6UX04 14 166 Pro_isomerase (PF00160)
t 197 223 O15541 197 223 zf-CCCH (PF00642)
t 262 306 O15541 262 306 zf-C3HC4_3 (PF13920)
T 455 561 Q9HCG8 455 561 MA3 (PF02847)
U 19 802 O60306 19 802 Aquarius_N (PF16399)
u 398 452 O75533 398 452 SF3b1 (PF08920)
U 801 1107 O60306 801 1107 AAA_11 (PF13086)
U 1115 1308 O60306 1115 1308 AAA_12 (PF13087)
V 13 163 Q9Y3C6 13 163 Pro_isomerase (PF00160)
v 76 592 Q15393 76 592 MMS1_N (PF10433)
v 863 1184 Q15393 863 1184 CPSF_A (PF03178)
W 2 163 P09661 2 163 LRR_9 (PF14580)
w 39 94 Q9ULR0 39 94 Isy1 (PF06246)
x 3 79 Q9BWJ5 3 79 SF3b10 (PF07189)
X 12 83 P08579 9 80 RRM_1 (PF00076)
X 153 219 P08579 153 219 RRM_1 (PF00076)
y 2 101 Q7RTV0 2 101 PHF5 (PF03660)
Y 46 117 Q8IYB3 46 117 PWI (PF01480)
z 21 88 Q9Y3B4 21 88 RRM_1 (PF00076)

Note: This mapping was provided by the PDBe group.

View structure

View Pfam families and other data mapped to the structure of PDB entry 6ff7 in InterPro