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1  structure 1  species 0  interactions 47  sequences 37  architectures

Structure: 6ICZ

Summary

6icz
PDB entry 6icz: Cryo-EM structure of a human post-catalytic spliceosome (P complex) at 3.0 angstrom
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PDB entry 6icz

Cryo-em structure of a human post-catalytic spliceosome (p complex) at 3.0 angstrom

Experiment type: Electron Microscopy, resolution 3.00Å
Release date: 2020-10-14
Authors: Zhang, X., Zhan, X., Yan, C., Shi, Y.
Species: Homo sapiens (Human)

PDBprint

Below is the PDBprint for entry 6icz.

External database links

Domain organisation

Many structures in the PDB are linked to one or more UniProt protein sequence entries. This section shows the Pfam domains which are found on the UniProt sequence(s) referred to by this structure.

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Sequence mapping

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from PDBe, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the sequences and Pfam domains that correspond to this structure.

PDB UniProt Pfam family
Chain Start End ID Start End
a 8 73 P62318 8 73 LSM (PF01423)
A 58 209 Q6P2Q9 58 209 PRO8NT (PF08082)
A 395 801 Q6P2Q9 395 801 PROCN (PF08083)
A 986 1077 Q6P2Q9 986 1077 RRM_4 (PF10598)
A 1210 1343 Q6P2Q9 1210 1343 U5_2-snRNA_bdg (PF10597)
A 1442 1600 Q6P2Q9 1442 1600 U6-snRNA_bdg (PF10596)
A 1760 1989 Q6P2Q9 1760 1989 PRP8_domainIV (PF12134)
A 2099 2205 Q6P2Q9 2099 2205 JAB (PF01398)
A 2212 2333 Q6P2Q9 2212 2333 PROCT (PF08084)
b 7 82 P14678 7 82 LSM (PF01423)
c 5 70 P62314 5 70 LSM (PF01423)
C 56 110 Q15029 56 110 EFTUD2 (PF16004)
C 127 440 Q15029 127 440 GTP_EFTU (PF00009)
C 489 566 Q15029 489 566 GTP_EFTU_D2 (PF03144)
C 584 656 Q15029 584 656 EFG_III (PF14492)
C 703 824 Q15029 703 824 EFG_IV (PF03764)
C 826 915 Q15029 826 915 EFG_C (PF00679)
d 33 111 P62316 33 111 LSM (PF01423)
D 482 663 O75643 482 663 DEAD (PF00270)
D 703 860 O75643 703 860 Helicase_C (PF00271)
D 981 1285 O75643 981 1285 Sec63 (PF02889)
D 1329 1514 O75643 1329 1514 DEAD (PF00270)
D 1812 2123 O75643 1812 2123 Sec63 (PF02889)
e 23 89 P62304 23 89 LSM (PF01423)
E 56 94 Q96DI7 56 94 WD40 (PF00400)
E 99 137 Q96DI7 99 137 WD40 (PF00400)
E 141 180 Q96DI7 141 180 WD40 (PF00400)
E 186 221 Q96DI7 186 221 WD40 (PF00400)
E 224 263 Q96DI7 224 263 WD40 (PF00400)
E 271 313 Q96DI7 271 313 WD40 (PF00400)
E 317 353 Q96DI7 317 353 WD40 (PF00400)
f 9 74 P62306 9 74 LSM (PF01423)
g 7 72 P62308 7 72 LSM (PF01423)
h 8 73 P62318 8 73 LSM (PF01423)
i 7 82 P14678 7 82 LSM (PF01423)
I 256 282 Q9HCS7 256 282 TPR_8 (PF13181)
I 395 428 Q9HCS7 395 428 TPR_8 (PF13181)
j 5 70 P62314 5 70 LSM (PF01423)
J 256 288 Q9BZJ0 256 288 HAT (PF02184)
J 357 388 Q9BZJ0 357 388 HAT (PF02184)
K 13 199 O75934 13 199 BCAS2 (PF05700)
k 33 111 P62316 33 111 LSM (PF01423)
L 11 71 Q99459 11 71 Myb_DNA-bind_6 (PF13921)
l 23 89 P62304 23 89 LSM (PF01423)
L 63 108 Q99459 63 108 Myb_DNA-bind_6 (PF13921)
L 502 629 Q99459 502 629 Myb_Cef (PF11831)
m 9 74 P62306 9 74 LSM (PF01423)
M 114 238 O95926 114 238 SYF2 (PF08231)
N 1 143 P41223 1 143 G10 (PF01125)
n 7 72 P62308 7 72 LSM (PF01423)
o 2 163 P09661 2 163 LRR_9 (PF14580)
O 234 299 Q9NW64 234 299 RRM_1 (PF00076)
P 2 229 Q9P013 2 229 Cwf_Cwc_15 (PF04889)
p 9 80 P08579 9 80 RRM_1 (PF00076)
q 3 57 Q9UMS4 3 57 U-box (PF04564)
Q 19 802 O60306 19 802 Aquarius_N (PF16399)
q 67 134 Q9UMS4 67 134 Prp19 (PF08606)
Q 801 1107 O60306 801 1107 AAA_11 (PF13086)
Q 1115 1308 O60306 1115 1308 AAA_12 (PF13087)
r 3 57 Q9UMS4 3 57 U-box (PF04564)
r 67 133 Q9UMS4 67 133 Prp19 (PF08606)
R 175 316 Q13573 175 316 SKIP_SNW (PF02731)
S 13 163 Q9Y3C6 13 163 Pro_isomerase (PF00160)
s 68 134 Q9UMS4 68 134 Prp19 (PF08606)
t 67 133 Q9UMS4 67 133 Prp19 (PF08606)
T 194 232 O43660 194 232 WD40 (PF00400)
T 236 274 O43660 236 274 WD40 (PF00400)
T 278 316 O43660 278 316 WD40 (PF00400)
T 320 358 O43660 320 358 WD40 (PF00400)
T 403 440 O43660 403 440 WD40 (PF00400)
u 62 228 P38919 62 228 DEAD (PF00270)
u 263 372 P38919 263 372 Helicase_C (PF00271)
v 5 146 Q96A72 7 148 Mago_nashi (PF02792)
V 455 559 Q9HCG8 455 559 MA3 (PF02847)
w 75 145 Q9Y5S9 75 145 RRM_1 (PF00076)
W 278 317 O60508 278 317 WD40 (PF00400)
W 322 360 O60508 322 360 WD40 (PF00400)
W 408 446 O60508 408 446 WD40 (PF00400)
W 496 536 O60508 496 536 WD40 (PF00400)
W 540 578 O60508 540 578 WD40 (PF00400)
X 51 142 Q9H875 51 142 DUF1168 (PF06658)
x 170 194 O15234 170 194 Btz (PF09405)
y 8 78 Q9UNP9 8 78 RRM_1 (PF00076)
Y 756 895 Q14562 756 895 Helicase_C (PF00271)
Y 957 1045 Q14562 957 1045 HA2 (PF04408)
Y 1103 1180 Q14562 1103 1180 OB_NTP_bind (PF07717)
Z 161 371 O95391 161 371 Slu7 (PF11708)

Note: This mapping was provided by the PDBe group.

View structure

View Pfam families and other data mapped to the structure of PDB entry 6icz in InterPro