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1  structure 1  species 0  interactions 76  sequences 76  architectures

Structure: 6OM0

Summary

PDB entry 6om0

Human ribosome nascent chain complex (pcsk9-rnc) stalled by a drug-like molecule with ap and pe trnas

Experiment type: Electron Microscopy, resolution 3.10Å
Release date: 2019-12-18
Authors: Li, W., Cate, J.H.D.
Species: Homo sapiens (Human)

PDBprint

Below is the PDBprint for entry 6om0.

External database links

Domain organisation

Many structures in the PDB are linked to one or more UniProt protein sequence entries. This section shows the Pfam domains which are found on the UniProt sequence(s) referred to by this structure.

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Sequence mapping

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from PDBe, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the sequences and Pfam domains that correspond to this structure.

PDB UniProt Pfam family
Chain Start End ID Start End
a 7 40 P61353 7 40 KOW (PF00467)
A 11 90 P62917 11 90 Ribosomal_L2 (PF00181)
a 52 136 P61353 52 136 Ribosomal_L27e (PF01777)
A 97 234 P62917 97 234 Ribosomal_L2_C (PF03947)
B 2 375 P39023 2 375 Ribosomal_L3 (PF00297)
b 26 145 P46776 26 145 Ribosomal_L27A (PF00828)
c 3 42 P47914 3 42 Ribosomal_L29e (PF01779)
C 22 263 P36578 22 263 Ribosomal_L4 (PF00573)
C 275 349 P36578 275 349 Ribos_L4_asso_C (PF14374)
d 12 106 P62888 12 106 Ribosomal_L7Ae (PF01248)
e 19 100 P62899 19 100 Ribosomal_L31e (PF01198)
F 14 176 P46777 14 176 Ribosomal_L5e (PF17144)
f 17 124 P62910 17 124 Ribosomal_L32e (PF01655)
F 236 289 P46777 236 289 Ribosomal_L18_c (PF14204)
g 5 104 P18077 5 104 Ribosomal_L35Ae (PF01247)
G 42 95 Q02878 42 95 Ribosomal_L6e_N (PF03868)
G 181 288 Q02878 181 288 Ribosomal_L6e (PF01159)
h 2 96 P49207 2 96 Ribosomal_L34e (PF01199)
H 24 85 P18124 24 85 Ribosomal_L30_N (PF08079)
H 90 140 P18124 90 140 Ribosomal_L30 (PF00327)
i 7 63 P42766 7 63 Ribosomal_L29 (PF00831)
I 122 216 P62424 122 216 Ribosomal_L7Ae (PF01248)
j 5 99 Q9Y3U8 5 99 Ribosomal_L36e (PF01158)
J 12 87 P32969 12 87 Ribosomal_L6 (PF00347)
J 99 178 P32969 99 178 Ribosomal_L6 (PF00347)
k 2 54 P61927 2 54 Ribosomal_L37e (PF01907)
K 12 166 P27635 12 166 Ribosomal_L16 (PF00252)
l 2 69 P63173 2 69 Ribosomal_L38e (PF01781)
L 10 63 P62913 10 63 Ribosomal_L5 (PF00281)
L 67 165 P62913 67 165 Ribosomal_L5_C (PF00673)
M 8 187 P26373 8 187 Ribosomal_L13e (PF01294)
m 9 50 P62891 9 50 Ribosomal_L39 (PF00832)
N 46 120 P50914 46 120 Ribosomal_L14e (PF01929)
n 78 127 P62987 78 127 Ribosomal_L40e (PF01020)
o 1 25 P62945 1 25 Ribosomal_L41 (PF05162)
O 2 191 P61313 2 191 Ribosomal_L15e (PF00827)
P 5 111 P40429 5 111 Ribosomal_L13 (PF00572)
p 17 94 P83881 17 94 Ribosomal_L44 (PF00935)
q 4 88 P61513 4 88 Ribosomal_L37ae (PF01780)
Q 17 151 P18621 17 151 Ribosomal_L22 (PF00237)
R 2 188 Q07020 2 188 Ribosomal_L18 (PF17135)
r 5 120 P46779 5 120 Ribosomal_L28e (PF01778)
S 3 146 P84098 3 146 Ribosomal_L19e (PF01280)
Sa 2 103 P62854 2 103 Ribosomal_S26e (PF01283)
SA 18 118 P08865 18 118 Ribosomal_S2 (PF00318)
SA 111 184 P08865 111 184 Ribosomal_S2 (PF00318)
SA 202 223 P08865 202 223 40S_SA_C (PF16122)
SB 21 221 P61247 21 221 Ribosomal_S3Ae (PF01015)
Sb 28 82 P42677 28 82 Ribosomal_S27e (PF01667)
Sc 7 68 P62857 7 68 Ribosomal_S28e (PF01200)
SC 102 166 P15880 102 166 Ribosomal_S5 (PF00333)
SC 186 259 P15880 186 259 Ribosomal_S5_C (PF03719)
Sd 6 55 P62273 6 55 Ribosomal_S14 (PF00253)
SD 20 96 P23396 20 96 KH_2 (PF07650)
SD 105 188 P23396 105 188 Ribosomal_S3_C (PF00189)
Se 2 58 P62861 2 58 Ribosomal_S30 (PF04758)
SE 3 39 P62701 3 39 RS4NT (PF08071)
SE 42 90 P62701 42 90 S4 (PF01479)
SE 95 169 P62701 95 169 Ribosomal_S4e (PF00900)
SE 177 211 P62701 177 211 KOW (PF00467)
SE 212 259 P62701 212 259 40S_S4_C (PF16121)
SF 51 204 P46782 51 204 Ribosomal_S7 (PF00177)
Sf 102 147 P62979 102 147 Ribosomal_S27 (PF01599)
SG 1 126 P62753 1 126 Ribosomal_S6e (PF01092)
Sg 5 44 P63244 5 44 WD40 (PF00400)
Sg 53 91 P63244 53 91 WD40 (PF00400)
Sg 95 133 P63244 95 133 WD40 (PF00400)
Sg 136 178 P63244 136 178 WD40 (PF00400)
Sg 182 220 P63244 182 220 WD40 (PF00400)
Sg 224 260 P63244 224 260 WD40 (PF00400)
Sg 273 311 P63244 273 311 WD40 (PF00400)
SH 7 189 P62081 7 189 Ribosomal_S7e (PF01251)
SI 5 190 P62241 5 190 Ribosomal_S8e (PF01201)
SJ 9 107 P46781 9 107 Ribosomal_S4 (PF00163)
SJ 108 154 P46781 108 154 S4 (PF01479)
SK 3 98 P46783 3 98 S10_plectin (PF03501)
SL 5 73 P62280 5 73 Ribosomal_S17_N (PF16205)
SL 75 144 P62280 75 144 Ribosomal_S17 (PF00366)
SM 16 111 P25398 16 111 Ribosomal_L7Ae (PF01248)
SN 2 60 P62277 2 60 Ribosomal_S13_N (PF08069)
SN 70 149 P62277 70 149 Ribosomal_S15 (PF00312)
SO 29 147 P62263 29 147 Ribosomal_S11 (PF00411)
SP 43 128 P62841 43 128 Ribosomal_S19 (PF00203)
SQ 14 146 P62249 14 146 Ribosomal_S9 (PF00380)
SR 2 122 P08708 2 122 Ribosomal_S17e (PF00833)
SS 14 142 P62269 14 142 Ribosomal_S13 (PF00416)
ST 5 141 P39019 5 141 Ribosomal_S19e (PF01090)
SU 21 115 P60866 21 115 Ribosomal_S10 (PF00338)
SV 1 80 P63220 1 80 Ribosomal_S21e (PF01249)
SW 5 130 P62244 5 130 Ribosomal_S8 (PF00410)
SX 29 142 P62266 29 142 Ribosom_S12_S23 (PF00164)
SY 24 102 P62847 24 102 Ribosomal_S24e (PF01282)
SZ 43 112 P62851 43 112 Ribosomal_S25 (PF03297)
T 7 130 Q02543 7 130 Ribosomal_L18A (PF01775)
U 2 101 P46778 2 101 Ribosomal_L21e (PF01157)
V 18 116 P35268 18 116 Ribosomal_L22e (PF01776)
W 20 140 P62829 20 140 Ribosomal_L14 (PF00238)
X 2 62 P83731 2 62 Ribosomal_L24e (PF01246)
Y 39 67 P62750 39 67 Ribosomal_L23eN (PF03939)
Y 75 148 P62750 75 148 Ribosomal_L23 (PF00276)
Z 8 122 P61254 8 122 Ribosomal_L26 (PF16906)
Z 51 97 P61254 51 97 KOW (PF00467)

Note: This mapping was provided by the PDBe group.

View structure

View Pfam families and other data mapped to the structure of PDB entry 6om0 in InterPro