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Structure: 6WX8

Summary

6wx8
PDB entry 6wx8: SOX2 bound to Importin-alpha 3
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PDB entry 6wx8

Sox2 bound to importin-alpha 3

Experiment type: X-ray diffraction, resolution 2.30Å
Release date: 2020-10-28
Authors: Bikshapathi, J., Stewart, M., Forwood, J.K., Aragao, D., Roman, N.
Species: Homo sapiens (Human)

PDBprint

Below is the PDBprint for entry 6wx8.

External database links

Domain organisation

Many structures in the PDB are linked to one or more UniProt protein sequence entries. This section shows the Pfam domains which are found on the UniProt sequence(s) referred to by this structure.

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Sequence mapping

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from PDBe, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the sequences and Pfam domains that correspond to this structure.

PDB UniProt Pfam family
Chain Start End ID Start End
A 67 93 O00629 67 93 IBB (PF01749)
A 103 144 O00629 103 144 Arm (PF00514)
A 146 186 O00629 146 186 Arm (PF00514)
A 188 229 O00629 188 229 Arm (PF00514)
A 232 271 O00629 232 271 Arm (PF00514)
A 273 313 O00629 273 313 Arm (PF00514)
A 315 355 O00629 315 355 Arm (PF00514)
A 357 397 O00629 357 397 Arm (PF00514)
A 400 440 O00629 400 440 Arm (PF00514)
A 447 485 O00629 447 485 Arm_3 (PF16186)
B 41 109 P48431 41 109 HMG_box (PF00505)
B 110 120 P48431 110 120 SOXp (PF12336)
C 70 93 O00629 70 93 IBB (PF01749)
C 103 144 O00629 103 144 Arm (PF00514)
C 146 186 O00629 146 186 Arm (PF00514)
C 188 229 O00629 188 229 Arm (PF00514)
C 232 271 O00629 232 271 Arm (PF00514)
C 273 313 O00629 273 313 Arm (PF00514)
C 315 355 O00629 315 355 Arm (PF00514)
C 357 397 O00629 357 397 Arm (PF00514)
C 400 440 O00629 400 440 Arm (PF00514)
C 447 486 O00629 447 486 Arm_3 (PF16186)
D 41 109 P48431 41 109 HMG_box (PF00505)
D 110 120 P48431 110 120 SOXp (PF12336)

Note: This mapping was provided by the PDBe group.

View structure

View Pfam families and other data mapped to the structure of PDB entry 6wx8 in InterPro