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Structure: 6BFC

Summary

6bfc
PDB entry 6bfc: Cryo-EM structure of human insulin degrading enzyme in complex with insulin
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PDB entry 6bfc

Cryo-em structure of human insulin degrading enzyme in complex with insulin

Experiment type: Electron Microscopy, resolution 3.70Å
Release date: 2019-12-18
Authors: Liang, W.G., Zhang, Z., Bailey, L.J., Kossiakoff, A.A., Tan, Y.Z., Wei, H., Carragher, B., Potter, S.C., Tang, W.J.
Species: Homo sapiens (Human)

PDBprint

Below is the PDBprint for entry 6bfc.

External database links

Domain organisation

Many structures in the PDB are linked to one or more UniProt protein sequence entries. This section shows the Pfam domains which are found on the UniProt sequence(s) referred to by this structure.

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Sequence mapping

For those sequences which have a structure in the Protein DataBank, we use the mapping between UniProt, PDB and Pfam coordinate systems from PDBe, to allow us to map Pfam domains onto UniProt three-dimensional structures. The table below shows the sequences and Pfam domains that correspond to this structure.

PDB UniProt Pfam family
Chain Start End ID Start End
a 4 49 P01308 28 98 Insulin (PF00049)
A 74 212 P14735 74 212 Peptidase_M16 (PF00675)
A 237 417 P14735 237 417 Peptidase_M16_C (PF05193)
A 422 703 P14735 422 703 Peptidase_M16_M (PF16187)
A 706 889 P14735 706 889 Peptidase_M16_C (PF05193)
b 4 49 P01308 28 98 Insulin (PF00049)
B 74 212 P14735 74 212 Peptidase_M16 (PF00675)
B 237 417 P14735 237 417 Peptidase_M16_C (PF05193)
B 422 703 P14735 422 703 Peptidase_M16_M (PF16187)
B 706 889 P14735 706 889 Peptidase_M16_C (PF05193)

Note: This mapping was provided by the PDBe group.

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View Pfam families and other data mapped to the structure of PDB entry 6bfc in InterPro